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| Product | Description | |
|---|---|---|
| foretinib | Potent inhibitor of MET, VEGFR2, Ron and AXL (IC50 values are 0.4, 0.9, 3 and 11 nM, respectively). Also potently inhibits Tie-2, Flt-1, Flt-3, Flt-4, KIT, PDGFRalpha and PDGFRbeta. Inhibits migration and invasion of B16F10 melanoma cells in vitro. Suppresses B16F10 tumor growth and metastasis in mice. Synonyms: XL880; XL 880; XL-880; GSK1363089; GSK 1363089; GSK-1363089; GSK089; EXEL2880; Foretinib. CAS No. 849217-64-7. Molecular formula: C34H34F2N4O6. Mole weight: 632.665. |  |
| Foretinib | Foretinib, also known as EXEL-2880, XL880, and GSK1363089, is a small-molecule inhibitor of the hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF) receptor tyrosine kinase families. Group: Biochemicals. Alternative Names: EXEL-2880, XL880, GSK1363089. Grades: Purified. CAS No. 849217-64-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences. |  Worldwide |
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