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| Product | Description | |
|---|---|---|
| formate dehydrogenase | The enzyme from most aerobic organisms is devoid of redox-active centres but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centres, flavin and a molybdenum centre. Together with EC 1.12.1.2 hydrogen dehydrogenase, forms a system previously known as formate hydrogenlyase. Group: Enzymes. Synonyms: formate-NAD oxidoreductase; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase. Enzyme Commission Number: EC 1.2.1.2. CAS No. 9028-85-7. FDH. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1125; formate dehydrogenase; EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase. Cat No: EXWM-1125. |  |
| Formate dehydrogenase | Formate dehydrogenase is an enzyme ubiquitous in prokaryotes and eukaryotes that catalyzes the reversible oxidation of formate to carbon dioxide. According to its metal content, structure and catalytic strategy, Formate dehydrogenase can be divided into two categories, non-metallic and metal-containing, which are often used in biochemical research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9028-85-7. Pack Sizes: 50 U; 100 U. Product ID: HY-P2907. |  |
| formate dehydrogenase (acceptor) | Formate dehydrogenase H is a cytoplasmic enzyme that oxidizes formate without oxygen transfer, transferring electrons to a hydrogenase. The two enzymes form the formate-hydrogen lyase complex. The enzyme contains an [4Fe-4S] cluster, a selenocysteine residue and a molybdopterin cofactor. Group: Enzymes. Synonyms: FDHH; FDH-H; FDH-O; formate dehydrogenase H; formate dehydrogenase O. Enzyme Commission Number: EC 1.1.99.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0462; formate dehydrogenase (acceptor); EC 1.1.99.33; FDHH; FDH-H; FDH-O; formate dehydrogenase H; formate dehydrogenase O. Cat No: EXWM-0462. | |
| formate dehydrogenase (coenzyme F420) | The enzyme from methanogenic archaea is a involved in formate-dependent H2 production. It contains noncovalently bound FAD. Group: Enzymes. Synonyms: coenzyme F420 reducing formate dehydrogenase; coenzyme F420-dependent formate dehydrogenase. Enzyme Commission Number: EC 1.2.99.9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1237; formate dehydrogenase (coenzyme F420); EC 1.2.99.9; coenzyme F420 reducing formate dehydrogenase; coenzyme F420-dependent formate dehydrogenase. Cat No: EXWM-1237. | |
| Formate Dehydrogenase (Crude Enzyme) | Formate Dehydrogenases are a set of enzymes that catalyse the oxidation of formate to carbon dioxide, donating the electrons to a second substrate, such as NAD + in formate:NAD + oxidoreductase (EC 1. 2. 1. 2) or to a cytochrome in formate:ferricytochrome-b1 oxidoreductase (EC 1. 2. 2. 1). This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Synthesis; biotechnology; medicine; analysis. Group: Enzymes. Synonyms: formate-NAD oxidoreductase; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase. Enzyme Commission Number: EC 1.2.1.2. CAS No. 9028-85-7. FDH. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. formate-NAD oxidoreductase; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase. Pack: 100ml. Cat No: NATE-1799. | |
| formate dehydrogenase (cytochrome) | This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is formate:ferricytochrome-b1 oxidoreductase. Other names in common use include formate dehydrogenase, and formate:cytochrome b1 oxidoreductase. This enzyme participates in glyoxylate and dicarboxylate metabolism. Group: Enzymes. Synonyms: formate dehydrogenase; formate:cytochrome b1 oxidoreductase. Enzyme Commission Number: EC 1.2.2.1. CAS No. 37251-01-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1203; formate dehydrogenase (cytochrome); EC 1.2.2.1; 37251-01-7; formate dehydrogenase; formate:cytochrome b1 oxidoreductase. Cat No: EXWM-1203. | |
| formate dehydrogenase (cytochrome-c-553) | Yeast cytochrome c, ferricyanide and phenazine methosulfate can act as acceptor. Group: Enzymes. Enzyme Commission Number: EC 1.2.2.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1204; formate dehydrogenase (cytochrome-c-553); EC 1.2.2.3. Cat No: EXWM-1204. | |
| Formate Dehydrogenase from Recombinant E. coli | Formate dehydrogenase is involved in the stress response of plants and catalyzes the reduction of NAD+ to NADH. Group: Enzymes. Synonyms: EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase. Enzyme Commission Number: EC 1.2.1.2. CAS No. 9028-85-7. Purity: 5% - 25%. FDH. Activity: 0.5-2.0 u/mg. Storage: 0-10°C. Form: Powder. Source: E. coli. EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase. Cat No: NATE-1783. | |
| formate dehydrogenase-N | The enzyme contains molybdopterin-guanine dinucleotides, five [4Fe-4S] clusters and two heme b groups. Formate dehydrogenase-N oxidizes formate in the periplasm, transferring electrons via the menaquinone pool in the cytoplasmic membrane to a dissimilatory nitrate reductase (EC 1.7.5.1), which transfers electrons to nitrate in the cytoplasm. The system generates proton motive force under anaerobic conditions. Group: Enzymes. Synonyms: Fdh-N; FdnGHI; nitrate-inducible formate dehydrogenase; formate dehydrogenase N; FDH-N; nitrate inducible Fdn; nitrate inducible formate dehydrogenase. Enzyme Commission Number: EC 1.1.5.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0434; formate dehydrogenase-N; EC 1.1.5.6; Fdh-N; FdnGHI; nitrate-inducible formate dehydrogenase; formate dehydrogenase N; FDH-N; nitrate inducible Fdn; nitrate inducible formate dehydrogenase. Cat No: EXWM-0434. | |
| formate dehydrogenase (NAD+, ferredoxin) | The enzyme complex, isolated from the bacterium Gottschalkia acidurici, couples the reduction of NAD+ and the reduction of ferredoxin with formate via flavin-based electron bifurcation. Group: Enzymes. Synonyms: electron-bifurcating formate dehydrogenase. Enzyme Commission Number: EC 1.2.1.93. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1197; formate dehydrogenase (NAD+, ferredoxin); EC 1.2.1.93; electron-bifurcating formate dehydrogenase. Cat No: EXWM-1197. | |
| formate dehydrogenase (NADP+) | A tungsten-selenium-iron protein. Group: Enzymes. Synonyms: NADP-dependent formate dehydrogenase; formate dehydrogenase (NADP). Enzyme Commission Number: EC 1.2.1.43. CAS No. 51377-43-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1147; formate dehydrogenase (NADP+); EC 1.2.1.43; 51377-43-6; NADP-dependent formate dehydrogenase; formate dehydrogenase (NADP). Cat No: EXWM-1147. | |
| Formate Dehydrogenases | recycling NADH. Group: Enzymes. Synonyms: Formate Dehydrogenases; FDH. Form: Enzyme Powder: 4 items*50mg / item, or other quantity. Formate Dehydrogenases; FDH; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-016. | |
| Native Candida boidinii Formate Dehydrogenase | Formate dehydrogenase is involved in the stress response of plants and catalyzes the reduction of NAD+ to NADH. Fdh is an abundant enzyme from yeast candida boidinii (cbfdh) that plays an important role in the energy supply of methylotrophic microorganisms and in the stress response of plants. Applications: Formate dehydrogenase (fdh) is used for diagnostics in large scale industrial pr ocesses. its used in the production of an unnatural amino acid, tert-l-leucine, a component of some hiv protease and matrix metalloprotease inhibitors. Group: Enzymes. Synonyms: EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate. Enzyme Commission Number: EC 1.2.1.2. CAS No. 9028-85-7. FDH. Activity: Type I, 5.0-15.0 units/mg protein; Type II, 0.3-0.6 units/mg; Type III, ~50 U/mL. Storage: -20°C. Form: Type I, lyophilized powder; Type II, powder; Type III, clear brown liquid. Source: Candida boidinii. EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase. Cat No: NATE-0254. | |
| Native Yeast Formate Dehydrogenase | Formate dehydrogenase is involved in the stress response of plants and catalyzes the reduction of NAD+ to NADH. Dehydrogenase that catalyzes the interconversion of formate to carbon dioxide. rely on the proven diagnostic quality of this product. Applications: Use formate dehydrogenase in diagnostic tests for the determination of oxalate in combination with oxalate decarboxylase or for the determination of formic acid. also used in cofactor recycling systems for nadh. Group: Enzymes. Synonyms: formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase. FDH. Activity: >0.4 U/mg. Stability: At +2 to +8°C within specification range for 12 months. Store dry. Appearance: White lyophilizate. Source: Yeast. EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase. Cat No: NATE-0978. | |
| formaldehyde dismutase | The enzyme contains a tightly but noncovalently bound NADP(H) cofactor, as well as Zn2+ and Mg2+. Enzyme-bound NADPH formed by oxidation of formaldehyde to formate is oxidized back to NADP+ by reaction with a second formaldehyde, yielding methanol. The enzyme from the bacterium Mycobacterium sp. DSM 3803 also catalyses the reactions of EC 1.1.99.36, alcohol dehydrogenase (nicotinoprotein) and EC 1.1.99.37, methanol dehydrogenase (nicotinoprotein). Formaldehyde and acetaldehyde can act as donors; formaldehyde, acetaldehyde and propanal can act as acceptors. Group: Enzymes. Synonyms: aldehyde dismutase; cannizzanase; nicotinoprotein aldehyde dismutase. Enzyme Commission Number: EC 1.2.98.1. CAS No. 85204-94-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1232; formaldehyde dismutase; EC 1.2.98.1; 85204-94-0; aldehyde dismutase; cannizzanase; nicotinoprotein aldehyde dismutase. Cat No: EXWM-1232. | |
| formate-tetrahydrofolate ligase | In eukaryotes occurs as a trifunctional enzyme also having methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) and methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) activity. Group: Enzymes. Synonyms: formyltetrahydrofolate synthetase; 10-formyltetrahydrofolate synthetase; tetrahydrofolic formylase; tetrahydrofolate formylase. Enzyme Commission Number: EC 6.3.4.3. CAS No. 9023-66-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5795; formate-tetrahydrofolate ligase; EC 6.3.4.3; 9023-66-9; formyltetrahydrofolate synthetase; 10-formyltetrahydrofolate synthetase; tetrahydrofolic formylase; tetrahydrofolate formylase. Cat No: EXWM-5795. | |
| methanol dehydrogenase (nicotinoprotein) | Contains Zn2+ and Mg2+. Nicotinoprotein methanol dehydrogenases have a tightly bound NADP+/NADPH cofactor that does not dissociate during the catalytic process. Instead, the cofactor is regenerated by a second substrate or electron carrier. While the in vivo electron acceptor is not known, N,N-dimethyl-4-nitrosoaniline (NDMA), which is reduced to 4-(hydroxylamino)-N,N-dimethylaniline, can serve this function in vitro. The enzyme has been detected in several Gram-positive methylotrophic bacteria, including Amycolatopsis methanolica, Rhodococcus rhodochrous and Rhodococcus erythropolis. These enzymes are decameric, and possess a 5-fold symmetry. Some of the enzymes can also dismutate formaldehyde to methanol and formate. Group: Enzymes. Synonyms: NDMA-dependent methanol dehydrogenase; nicotinoprotein methanol dehydrogenase; methanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase. Enzyme Commission Number: EC 1.1.99.37. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0465; methanol dehydrogenase (nicotinoprotein); EC 1.1.99.37; NDMA-dependent methanol dehydrogenase; nicotinoprotein methanol dehydrogenase; methanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase. Cat No: EXWM-0465. | |
| methenyltetrahydrofolate cyclohydrolase | In eukaryotes, the enzyme occurs as a trifunctional enzyme that also has methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) and formate-tetrahydrofolate ligase (EC 6.3.4.3) activity. In some prokaryotes, it occurs as a bifunctional enzyme that also has dehydrogenase (EC 1.5.1.5) activity or formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) activity. Group: Enzymes. Synonyms: Citrovorum factor cyclodehydrase; cyclohydrolase; formyl-methenyl-methylenetetrahydrofolate synthetase (combined); 5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing). Enzyme Commission Number: EC 3.5.4.9. CAS No. 9027-97-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4577; methenyltetrahydrofolate cyclohydrolase; EC 3.5.4.9; 9027-97-8; Citrovorum factor cyclodehydrase; cyclohydrolase; formyl-methenyl-methylenetetrahydrofolate synthetase (combined); 5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing). Cat No: EXWM-4577. | |
| methylenetetrahydrofolate dehydrogenase (NADP+) | In eukaryotes, occurs as a trifunctional enzyme also having methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) and formate-tetrahydrofolate ligase(EC 6.3.4.3) activity. In some prokaryotes occurs as a bifunctional enzyme also having methenyltetrahydrofolate cyclohydrolase activity (EC 3.5.4.9). Group: Enzymes. Synonyms: N5,N10-methylenetetrahydrofolate dehydrogenase; 5,10-methylenetetrahydrofolate:NADP oxidoreductase; 5,10-methylenetetrahydrofolate dehydrogenase; methylenetetrahydrofolate dehydrogenase; methylenetetrahydrofolate dehydrogenase (NADP). Enzyme Commission Number: EC 1.5.1.5. CAS No. 9029-14-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1531; methylenetetrahydrofolate dehydrogenase (NADP+); EC 1.5.1.5; 9029-14-5; N5,N10-methylenetetrahydrofolate dehydrogenase; 5,10-methylenetetrahydrofolate:NADP oxidoreductase; 5,10-methylenetetrahydrofolate dehydrogenase; methylenetetrahydrofolate dehydrogenase; methylenetetrahydrofolate dehydrogenase (NADP). Cat No: EXWM-1531. | |
| Native Pseudomonas sp. Formaldehyde Dehydrogenase | Formaldehyde dehydrogenase catalyzes the conversion of formaldehyde to formate. Applications: Formaldehyde dehydrogenase is used as a biosensor for the presence of formaldehyde in pharmaceuticals, waste water, vaccines and industrial products. it was also used in coupled pectin methyl esterase (pme) enzyme assay. Group: Enzymes. Synonyms: EC 1.2.1.46; Formaldehyde Dehydrogenase; NAD-linked formaldehyde dehydrogenase; NAD-dependent formaldehyde dehydrogenase; 9028-84-6. Enzyme Commission Number: EC 1.2.1.46. CAS No. 9028-84-6. Formaldehyde Dehydrogenase. Activity: 1.0-6.0 units/mg solid. Storage: -20°C. Form: Lyophilized powder containing ~70% stabilizers as Mg2+, Ca2+, bovine serum albumin, glycine, and lysine. Source: Pseudomonas sp. EC 1.2.1.46; Formaldehyde Dehydrogenase; NAD-linked formaldehyde dehydrogenase; NAD-dependent formaldehyde dehydrogenase; 9028-84-6. Cat No: NATE-0257. | |
| 2-amino-4-deoxychorismate dehydrogenase | The sequential action ofEC 2.6.1.86, 2-amino-4-deoxychorismate synthase and this enzyme leads to the formation of the benzoxazolinate moiety of the enediyne antitumour antibiotic C-1027. Group: Enzymes. Synonyms: ADIC dehydrogenase; 2-amino-2-deoxyisochorismate dehydrogenase; SgcG. Enzyme Commission Number: EC 1.3.99.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1426; 2-amino-4-deoxychorismate dehydrogenase; EC 1.3.99.24; ADIC dehydrogenase; 2-amino-2-deoxyisochorismate dehydrogenase; SgcG. Cat No: EXWM-1426. | |
| 2-amino-4-deoxychorismate synthase | Requires Mg2+. The reaction occurs in the reverse direction to that shown above. In contrast to most anthranilate-synthase I (ASI) homologues, this enzyme is not inhibited by tryptophan. In Streptomyces globisporus, the sequential action of this enzyme and EC 1.3.99.24, 2-amino-4-deoxychorismate dehydrogenase, leads to the formation of the benzoxazolinate moiety of the enediyne antitumour antibiotic C-1027.In certain Pseudomonads the enzyme participates in the biosynthesis of phenazine, a precursor for several compounds with antibiotic activity. Group: Enzymes. Synonyms: ADIC synthase; 2-amino-2-deoxyisochorismate synthase;SgcD. Enzyme Commission Number: EC 2.6.1.86. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2927; 2-amino-4-deoxychorismate synthase; EC 2.6.1.86; ADIC synthase; 2-amino-2-deoxyisochorismate synthase;SgcD. Cat No: EXWM-2927. | |
| 4-hydroxybenzaldehyde dehydrogenase (NAD+) | The bacterial enzyme (characterized from an unidentified denitrifying bacterium) is involved in an anaerobic toluene degradation pathway. The plant enzyme is involved in formation of 4-hydroxybenzoate, a cell wall-bound phenolic acid that plays a major role in plant defense against pathogens. cf. EC 1.2.1.96, 4-hydroxybenzaldehyde dehydrogenase (NADP+). Group: Enzymes. Synonyms: p-hydroxybenzaldehyde dehydrogenase (ambiguous); 4-hydroxybenzaldehyde dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.2.1.64. CAS No. 61229-72-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1166; 4-hydroxybenzaldehyde dehydrogenase (NAD+); EC 1.2.1.64; 61229-72-9; p-hydroxybenzaldehyde dehydrogenase (ambiguous); 4-hydroxybenzaldehyde dehydrogenase (ambiguous). Cat No: EXWM-1166. | |
| A37 | A37 is an aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor (IC50 = 4.6 μM; Ki = 300 nM). It competitively binds to the aldehyde binding pocket of ALDH1A1, resulting in the disruption of spheroid formation and a decrease of cell viability in ovarian cancer cells in vitro. Synonyms: Ethyl 2-[[3, 4-dihydro-4-oxo-3-[3- (1-pyrrolidinyl) propyl][1]benzothieno[3, 2-d]pyrimidin-2-yl]thio]acetate; CM037; CM-037; CM 037; A37; A-37; A 37. Grades: ≥97% by HPLC. CAS No. 896795-60-1. Molecular formula: C21H25N3O3S2. Mole weight: 431.57. |  |
| aspartate-semialdehyde dehydrogenase | In enzymology, an aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) is an enzyme that is very important in the biosynthesis of amino acids in prokaryotes, fungi, and some higher plants. It forms an early branch point in the metabolic pathway forming lysine, methionine, leucine and isoleucine from aspartate. This pathway also produces diaminopimelate which plays an essential role in bacterial cell wall formation. There is particular interest in ASADH as disabling this enzyme proves fatal to the organism giving rise to the possibility of a new class of antibiotics, fungicides, and herbicides aimed at inhibiting it. Group: Enzymes. Synonyms: aspartate semialdehyde dehydrogenase; aspartic semialdehyde dehydrogenase; L-aspartate-β-semialdehyde:NADP+ oxidoreductase (phosphorylating); aspartic β-semialdehyde dehydrogenase; ASA dehydrogenase. Enzyme Commission Number: EC 1.2.1.11. CAS No. 9000-98-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1117; aspartate-semialdehyde dehydrogenase; EC 1.2.1.11; 9000-98-0; aspartate semialdehyde dehydrogenase; aspartic semialdehyde dehydrogenase; L-aspartate-β-semialdehyde:NADP+ oxidoreductase (phosphorylating); aspartic β-semialdehyde dehydrogenase; ASA dehydrogenase. Cat No: EXWM-1117. | |
| bacteriochlorophyllide a dehydrogenase | The enzyme, together with EC 1.3.7.15, chlorophyllide-a reductase, and EC 4.2.1.165, chlorophyllide-a 31-hydratase, is involved in the conversion of chlorophyllide a to bacteriochlorophyllide a. The enzymes can act in multiple orders, resulting in the formation of different intermediates, but the final product of the cumulative action of the three enzymes is always bacteriochlorophyllide a. The enzyme oxidizes a hydroxyl group on ring A, converting it to an oxo group. Group: Enzymes. Synonyms: bchC (gene name). Enzyme Commission Number: EC 1.1.1.396. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0316; bacteriochlorophyllide a dehydrogenase; EC 1.1.1.396; bchC (gene name). Cat No: EXWM-0316. | |
| carboxynorspermidine synthase | The reaction takes place in the opposite direction. Part of a bacterial polyamine biosynthesis pathway. L-aspartate 4-semialdehyde and propane-1,3-diamine/putrescine form a Schiff base that is reduced to form carboxynorspermidine / carboxyspermidine, respectively. The enzyme from the bacterium Vibrio cholerae is essential for biofilm formation. The enzyme from Campylobacter jejuni only produces carboxyspermidine in vivo even though it also can produce carboxynorspermidine in vitro. Group: Enzymes. Synonyms: carboxynorspermidine dehydrogenase; carboxyspermidine dehydrogenase; CASDH; CANSDH; VC1624 (gene name). Enzyme Commission Number: EC 1.5.1.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1524; carboxynorspermidine synthase; EC 1.5.1.43; carboxynorspermidine dehydrogenase; carboxyspermidine dehydrogenase; CASDH; CANSDH; VC1624 (gene name). Cat No: EXWM-1524. | |
| chlorophyllide a 31-hydratase | The enzyme, together with EC 1.3.7.15, chlorophyllide-a reductase, and EC 1.1.1.396, bacteriochlorophyllide-a dehydrogenase, is involved in the conversion of chlorophyllide a to bacteriochlorophyllide a. The enzymes can act in multiple orders, resulting in the formation of different intermediates, but the final product of the cumulative action of the three enzymes is always bacteriochlorophyllide a. The enzyme catalyses the hydration of a vinyl group on ring A, converting it to a hydroxyethyl group. Group: Enzymes. Synonyms: bchF (gene name). Enzyme Commission Number: EC 4.2.1.165. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5006; chlorophyllide a 31-hydratase; EC 4.2.1.165; bchF (gene name). Cat No: EXWM-5006. | |
| chlorophyllide a reductase | The enzyme, together with EC 1.1.1.396, bacteriochlorophyllide-a dehydrogenase, and EC 4.2.1.165, chlorophyllide-a 31-hydratase, is involved in the conversion of chlorophyllide a to bacteriochlorophyllide a. These enzymes can act in multiple orders, resulting in the formation of different intermediates, but the final product of the cumulative action of the three enzymes is always bacteriochlorophyllide a. This enzyme catalyses a trans-reduction of the B-ring; the product has the (7R,8R)-configuration. In addition, the enzyme has a latent activity of EC 1.3.7.13, 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin). The enzyme contains a [4Fe-4S] cluster, and structurally resembles the Fe protein/MoFe protein complex of nitrogenase (EC 1.18.6.1), which catalyses an ATP-driven reduction. Group: Enzymes. Synonyms: bchX (gene name); bchY (gene name); bchZ (gene name); COR. Enzyme Commission Number: EC 1.3.7.15. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1396; chlorophyllide a reductase; EC 1.3.7.15; bchX (gene name); bchY (gene name); bchZ (gene name); COR. Cat No: EXWM-1396. | |
| Danshensu | Danshensu is an active component of Salvia miltiorrhiza that shows wide cardiovascular benefit. It suppresses the formation of reactive oxygen species and inhibits platelet adhesion and aggregation. It also protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation. It increases production of collagenin Detroit 551 cells and attenuates the α-MSH-stimulated melanin production of B16 cells. It may be used as active ingredients in would healing, cosmetic treatments or treating hyperpigmentation. It significantly decreased the level of the marker enzymes (creatine kinase and lactate dehydrogenase) from the coronary effluents and myocardial infarction size in vitro. It also had ROS scavenging activity and boosted endogenous antioxidants such as SOD, CAT, MDA, GSH-PX and HO-1 activities by activating nuclear factor erythroid-2-related factor 2 (Nrf2) signaling pathway which was mediated by Akt and ERK1/2 in western blot analysis. It significantly lowered tHcy in rats with elevated tHcy. Danshensu is a natural compound, which can also be used in cosmetics material. Synonyms: Benzenepropanoic acid, α,3,4-trihydroxy-, (αR)-; (αR)-α,3,4-Trihydroxybenzenepropanoic acid; Benzenepropanoic acid, α,3,4-trihydroxy-, (R)-; (R)-(+)-3-(3,4-Dihydroxyphenyl)lactic acid; (R)-3-(3,4-Dihydroxyphenyl)-2-hydroxypropionic acid; 3-(3',4'-Dihydroxyphenyl)-(2R)-lactic acid; D-(+)-β-(3,4-Dihydroxyphenyl)lactic acid; Dan Shen Su; Dan shen suan A; DS 182; Salianic acid A; Salvianic acid A; Tanshinol. Grades: >98%. CAS No. 76822-21-4. Molecular formula: C9H10O5. Mole weight: 198.17. | |
| Disulfiram | Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1) , used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. Disulfiram, a copper ion carrier,?with?Cu 2+ increases intracellular ROS levels and induces cuproptosis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tetraethylthiuram disulfide; TETD. CAS No. 97-77-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0240. | |
| geranylgeranylglycerol-phosphate geranylgeranyltransferase | This enzyme is an integral-membrane protein that carries out the second prenyltransfer reaction involved in the formation of polar membrane lipids in Archaea. Requires a divalent metal cation, such as Mg2+ or Mn2+, for activity. 4-Hydroxybenzoate, 1,4-dihydroxy 2-naphthoate, homogentisate and α-glycerophosphate cannot act as prenyl-acceptor substrates. The other enzymes involved in the biosynthesis of polar lipids in Archaea are EC 1.1.1.261 (sn-glycerol-1-phosphate dehydrogenase), EC 2.5.1.41 (phosphoglycerol geranylgeranyltransferase), which, together with this enzyme, alkylates the hydroxy groups of glycerol 1-phosphate to yield unsaturated archaetidic a...ranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase. Enzyme Commission Number: EC 2.5.1.42. CAS No. 124650-68-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2778; geranylgeranylglycerol-phosphate geranylgeranyltransferase; EC 2.5.1.42; 124650-68-6; geranylgeranyloxyglycerol phosphate geranylgeranyltransferase; geranylgeranyltransferase II; (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; DGGGP synthase; DGGGPS; geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase. Cat No: EXWM-2778. | |
| Glutaryl-L-Carnitine, Lithium Salt | A metabolite of L-Carnitine. Increased formation and excretion of glutarylcarnitin results from a glutaryl-CoA dehydrogenase deficiency, an inborn error of lysine and tryptophan metabolism. Secondary carnitine depletion due to increased formation and urinary excretion of glutarylcarnitine is suggested to play an important role in the neuropathogenesis of glutaryl-CoA dehydrogenase deficiency, inducing excitotoxic neuronal damage and mitochondrial dysfunction. Group: Biochemicals. Alternative Names: (2R)-3-Carboxy-2-(4-carboxy-1-oxobutoxy)-N,N,N-trimethyl-1-propanaminium inner salt; Glutarylcarnitine; L-Carnitine lithium glutarate. Grades: Highly Purified. CAS No. 102636-82-8 (free acid). Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Glycinamide ribonucleotide | Glycineamide ribonucleotide (or GAR) is an intermediate in de novo purine biosynthesis. It is formed from phosphoribosylamine by the enzyme phosphoribosylamine-glycine ligase. In the next step of purine biosynthesis the enzyme phosphoribosylglycinamide formyltransferase acts on GAR to form FGAR. GAR formation is stimulated by Luteinizing hormone (LH) and Chorionic gonadotropin (HCG) via activation of Glc-6-P-dehydrogenase. Synonyms: 5'-Phosphoribosylglycinamide; N1-(5-Phospho-D-ribosyl)glycinamide; [(2R,3S,4R,5R)-5-[(2-aminoacetyl)amino]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate; n-glycyl-5-o-phosphono-|A-d-ribofuranosylamine; 5'-phosphoribosylglycinamide; GAR; N1-(5-Phospho-D-ribosyl)glycinamide; N1-(5-phospho-beta-D-ribosyl)glycinamide. CAS No. 10074-18-7. Molecular formula: C7H15N2O8P. Mole weight: 286.18. | |
| L-sorbose 1-dehydrogenase | The product, L-sorbosone, is an intermediate in bacterial 2-keto-L-gulonic-acid formation. The activity of this membrane-bound enzyme is stimulated by Fe(III) or Co2+ but is inhibited by Cu2+. The enzyme is highly specific for L-sorboseas other sugars, such as glucose, mannitol and sorbitol, are not substrates. Phenazine methosulfate and DCIP can act as artificial acceptors. Group: Enzymes. Synonyms: SDH. Enzyme Commission Number: EC 1.1.99.32. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0461; L-sorbose 1-dehydrogenase; EC 1.1.99.32; SDH. Cat No: EXWM-0461. | |
| methylenetetrahydromethanopterin dehydrogenase | Coenzyme F420 is a 7,8-didemethyl-8-hydroxy-5-deazariboflavin derivative; methanopterin is a pterin analogue. The enzyme is involved in the formation of methane from CO2 in the methanogen Methanothermobacter thermautotrophicus. Group: Enzymes. Synonyms: N5,N10-methylenetetrahydromethanopterin dehydrogenase; 5,10-methylenetetrahydromethanopterin dehydrogenase. Enzyme Commission Number: EC 1.5.98.1. CAS No. 100357-01-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1564; methylenetetrahydromethanopterin dehydrogenase; EC 1.5.98.1; 100357-01-5; N5,N10-methylenetetrahydromethanopterin dehydrogenase; 5,10-methylenetetrahydromethanopterin dehydrogenase. Cat No: EXWM-1564. | |
| Mycophenolate Mofetil | Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. Mycophenolate mofetil inhibits de novo purine synthesis via the inhibition of inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil shows selective lymphocyte antiproliferative effects involve both T and B cells, preventing antibody formation [1]. Uses: Scientific research. Group: Natural products. Alternative Names: RS 61443; TM-MMF. CAS No. 128794-94-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 1 g; 5 g. Product ID: HY-B0199. | |
| Mycophenolate Mofetil-d4 | Mycophenolate Mofetil-d 4 is the deuterium labeled Mycophenolate Mofetil. Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. Mycophenolate mofetil inhibits de novo purine synthesis via the inhibition of inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil shows selective lymphocyte antiproliferative effects involve both T and B cells, preventing antibody formation[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1132748-21-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0199S. | |
| Mycophenolic Acid - CAS 24280-93-1 | An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP. Group: Fluorescence/luminescence spectroscopy. |  |
| Native Cellulomonas sp. Glycerol Dehydrogenase | Glycerol dehydrogenase is an enzyme in the oxidoreductase family that utilizes the NAD+ to catalyze the oxidation of glycerol to form glycerone (dihydroxyacetone). Applications: This enzyme is useful for enzymatic determination of glycerol and of triglyceride when coupled with lipoprotein lipase in clinical analysis. formation of nadh from the reaction of glycerol and nad+ was catalyzed by the enzyme glycerol dehydrogenase. Group: Enzymes. Synonyms: EC 1.1.1.6; NAD+-linked glycerol dehydrogenase; glycerol:NAD+ 2-oxidoreductase; GDH; GlDH; GlyDH; 9028-14-2; glycerin dehydrogenase. Enzyme Commission Number: EC 1.1.1.6. CAS No. 9028-14-2. GDH. Mole weight: mol wt ~390 kDa. Activity: 50-125 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing bovine serum albumin. Source: Cellulomonas sp. EC 1.1.1.6; NAD+-linked glycerol dehydrogenase; glycerol:NAD+ 2-oxidoreductase; GDH; GlDH; GlyDH; 9028-14-2; glycerin dehydrogenase. Cat No: NATE-0283. | |
| Native Xanthine Dehydrogenase from Bovine milk | Xanthine oxidoreductase (XOR) catalyzes the formation of uric acid from hypoxanthine and xanthine, last two steps of purine catabolism. The mammalian enzyme is synthesized as a xanthine dehydrogenase form (XDH, EC 1.17.1.4), which uses NAD as the electron acceptor, but is converted into an xanthine oxidase form (XO, EC 1.1.3.22) by reversible (through sulfhydryl group oxidation) or irreversible (proteolysis) manner. Since most industrial protocols of XOR purification includes proteolysis step, commercial XOR enzyme is available only as oxidase form unable to use NAD as a an electron acceptor. Group: Enzymes. Synonyms: xanthine dehydrogenase; NAD+-xanthine dehydrogenase; xanthine-NAD+ oxidoreductase; xanthine/NAD+ oxidoreductase; xanthine oxidoreductase; XDH; EC 1.17.1.4. Enzyme Commission Number: EC 1.17.1.4. CAS No. 9054-84-6. XDH. Form: Lyophilized. Source: Bovine milk. Species: Bovine. xanthine dehydrogenase; NAD+-xanthine dehydrogenase; xanthine-NAD+ oxidoreductase; xanthine/NAD+ oxidoreductase; xanthine oxidoreductase; XDH; EC 1.17.1.4. Cat No: NATE-1065. | |
| Oxalacetic Acid (Oxaloacetic acid) | A four carbon dicarboxylic acid that is an intermediate in the citric acid cycle and glucogenesis. It has been shown to inhibit succinate dehydrogenase. Oxaloacetic acid, in the form of its conjugate base oxaloacetate, is a metabolic intermediate in many processes that occur in animals. It takes part in the: gluconeogenesis, urea cycle, glyoxylate cycle, amino acid synthesis, fatty acid synthesis and citric acid cycle. Gluconeogenesis[1] is a metabolic pathway consisting of a series of eleven enzyme-catalyzed reactions, resulting in the generation of glucose from non-carbohydrates substrates. The beginning of this process takes place in the mitochondrial matrix, where pyruvate molecules are found. A pyruvate molecule is carboxylated by a pyruvate carboxylase enzyme, activated by a molecule each of ATP and water. This reaction results in the formation of oxaloacetate. NADH reduces oxaloacetate to malate. This transformation is needed to transport the molecule out of the mitochondria. On Group: Biochemicals. Alternative Names: Oxobutanedioic Acid; Oxalacetic Acid; 2-Ketosuccinic acid; 2-Oxobutanedioic acid; 2-Oxosuccinic Acid; Ketosuccinic Acid; NSC 284205; NSC 77688; OAA; Oxaloacetic Acid; Oxaloethanoic Acid; Oxosuccinic Acid; α-Ketosuccinic Acid. Grades: Reagent Grade. CAS No. 328-42-7. Pack Sizes: 25g, 50g, 100g, 250g. Molecular Formula: C?H?O?, Molecular Weight: 132.07. US Biological Life Sciences. | Worldwide |
| phosphoglycerol geranylgeranyltransferase | This cytosolic enzyme catalyses the first pathway-specific step in the biosynthesis of the core membrane diether lipids in archaebacteria. Requires Mg2+ for maximal activity. It catalyses the alkylation of the primary hydroxy group in sn-glycerol 1-phosphate by geranylgeranyl diphosphate (GGPP) in a prenyltransfer reaction where a hydroxy group is the nucleophile in the acceptor substrate. The other enzymes involved in the biosynthesis of polar lipids in Archaea are EC 1.1.1.261 (sn-glycerol-1-phosphate dehydrogenase), EC 2.5.1.42 (geranylgeranylglycerol-phosphate geranylgeranyltransferase) and EC 2.7.7.67 (CDP-archaeol synthase), which lead to the formation of CDP-unsat... Number: EC 2.5.1.41. CAS No. 124650-69-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2777; phosphoglycerol geranylgeranyltransferase; EC 2.5.1.41; 124650-69-7; glycerol phosphate geranylgeranyltransferase; geranylgeranyl-transferase (ambiguous); prenyltransferase (ambiguous); (S)-3-O-geranylgeranylglyceryl phosphate synthase; (S)-geranylgeranylglyceryl phosphate synthase; GGGP synthase; (S)-GGGP synthase; GGGPS; geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase; geranylgeranyl diphosphate:sn-glycerol-1-phosphate geranylgeranyltransferase. Cat No: EXWM-2777. | |
| precorrin-2 dehydrogenase | This enzyme catalyses the second of three steps leading to the formation of siroheme from uroporphyrinogen III. The first step involves the donation of two S-adenosyl-L-methionine-derived methyl groups to carbons 2 and 7 of uroporphyrinogen III to form precorrin-2 (EC 2.1.1.107, uroporphyrin-III C-methyltransferase) and the third step involves the chelation of ferrous iron to sirohydrochlorin to form siroheme (EC 4.99.1.4, sirohydrochlorin ferrochelatase). In Saccharomyces cerevisiae, the last two steps are carried out by a single bifunctional enzyme, Met8p. In some bacteria, steps 1-3 are catalysed by a single multifunctional protein called CysG, whereas in Bacillus megaterium, three separate enzymes carry out each of the steps, with SirC being responsible for the above reaction. Group: Enzymes. Synonyms: Met8p; SirC; CysG. Enzyme Commission Number: EC 1.3.1.76. CAS No. 227184-47-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1345; precorrin-2 dehydrogenase; EC 1.3.1.76; 227184-47-6; Met8p; SirC; CysG. Cat No: EXWM-1345. | |
| Pyridaben | Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I ( NADH dehydrogenase ) with an IC 50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 96489-71-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0817. | |
| Ribavirin | Ribavirin is a nucleoside analog that inhibits the replication of both DNA and RNA viruses, including influenza type A and type B. Ribavirin, as ribavirin 5-phosphate, affects virus-infected cells primarily by inhibiting the enzyme inosine 5-monophosphate (IMP) dehydrogenase. It potently suppresses eIF4E-mediated oncogenic transformation of murine cells in vitro, of tumor growth of a mouse model of eIF4E-dependent human squamous cell carcinoma in vivo, and of colony formation of eIF4E-dependent acute myelogenous leukemia cells derived from human patients. Group: Biochemicals. Alternative Names: 1-ß-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, ICN-1229, Rebetol, Viramid, Virazid, Virazole. Grades: Highly Purified. CAS No. 36791-04-5. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C8H12N4O5, Molecular Weight: 244.2. US Biological Life Sciences. | Worldwide |
| S-(hydroxymethyl)glutathione dehydrogenase | The substrate, S-(hydroxymethyl)glutathione, forms spontaneously from glutathione and formaldehyde; its rate of formation is increased in some bacteria by the presence of EC 4.4.1.22, S-(hydroxymethyl)glutathione synthase. This enzyme forms part of the pathway that detoxifies formaldehyde, since the product is hydrolysed by EC 3.1.2.12, S-formylglutathione hydrolase. The human enzyme belongs to the family of zinc-dependent alcohol dehydrogenases. Also specifically reduces S-nitrosylglutathione. Group: Enzymes. Synonyms: NAD-linked formaldehyde dehydrogenase (incorrect); formaldehyde dehydrogenase (incorrect); formic dehydrogenase (incorrect); class III . Enzyme Commission Number: EC 1.1.1.284. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0192; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.284; NAD-linked formaldehyde dehydrogenase (incorrect); formaldehyde dehydrogenase (incorrect); formic dehydrogenase (incorrect); class III alcohol dehydrogenase; ADH3; χ-ADH; FDH (incorrect); formaldehyde dehydrogenase (glutathione) (incorrect); GS-FDH (incorrect); glutathione-dependent formaldehyde dehydrogenase (incorrect); NAD-dependent formaldehyde dehydrogenase; GD-FALDH; NAD- and glutathione-dependent formaldehyde dehydrogenase. Cat No: EXWM-0192. | |
| sirohydrochlorin ferrochelatase | This enzyme catalyses the third of three steps leading to the formation of siroheme from uroporphyrinogen III. The first step involves the donation of two S-adenosyl-L-methionine-derived methyl groups to carbons 2 and 7 of uroporphyrinogen III to form precorrin-2 (EC 2.1.1.107, uroporphyrin-III C-methyltransferase) and the second step involves an NAD+-dependent dehydrogenation to form sirohydrochlorin from precorrin-2 (EC 1.3.1.76, precorrin-2 dehydrogenase). In Saccharomyces cerevisiae, the last two steps are carried out by a single bifunctional enzyme, Met8p. In some bacteria, steps 1-3 are catalysed by a single multifunctional protein called CysG, whereas in Bacillus megaterium, three separate enzymes carry out each of the steps, with SirB being responsible for the above reaction. Group: Enzymes. Synonyms: CysG; Met8P; SirB; sirohydrochlorin ferro-lyase (incorrect). Enzyme Commission Number: EC 4.99.1.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5361; sirohydrochlorin ferrochelatase; EC 4.99.1.4; CysG; Met8P; SirB; sirohydrochlorin ferro-lyase (incorrect). Cat No: EXWM-5361. | |
| sn-glycerol-1-phosphate dehydrogenase | This enzyme is found primarily as a Zn2+-dependent form in archaea but a Ni2+-dependent form has been found in Gram-positive bacteria. The Zn2+-dependent metalloenzyme is responsible for the formation of archaea-specific sn-glycerol-1-phosphate, the first step in the biosynthesis of polar lipids in archaea. It is the enantiomer of sn-glycerol 3-phosphate, the form of glycerophosphate found in bacteria and eukaryotes. The other enzymes involved in the biosynthesis of polar lipids in archaea are EC 2.5.1.41 (phosphoglycerol geranylgeranyltransferase) and EC 2.5.1.42 (geranylgeranylglycerol-phosphate geranylgeranyltransferase), which together alkylate the hydroxy groups of gl...oval of CMP, leading to the production of unsaturated archaetidylserine. Activity of the enzyme is stimulated by K+. Group: Enzymes. Synonyms: glycerol-1-phosphate dehydrogenase [NAD(P)+]; sn-glycerol-1-phosphate:NAD+ oxidoreductase; G-1-P dehydrogenase; Gro1PDH; AraM. Enzyme Commission Number: EC 1.1.1.261. CAS No. 204594-18-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0167; sn-glycerol-1-phosphate dehydrogenase; EC 1.1.1.261; 204594-18-3; glycerol-1-phosphate dehydrogenase [NAD(P)+]; sn-glycerol-1-phosphate:NAD+ oxidoreductase; G-1-P dehydrogenase; Gro1PDH; AraM. Cat No: EXWM-0167. | |
| uroporphyrinogen-III C-methyltransferase | This enzyme catalyses two sequential methylation reactions, the first forming precorrin-1 and the second leading to the formation of precorrin-2. It is the first of three steps leading to the formation of siroheme from uroporphyrinogen III. The second step involves an NAD+-dependent dehydrogenation to form sirohydrochlorin from precorrin-2 (EC 1.3.1.76, precorrin-2 dehydrogenase) and the third step involves the chelation of Fe2+ to sirohydrochlorin to form siroheme (EC 4.99.1.4, sirohydrochlorin ferrochelatase). In Saccharomyces cerevisiae, the last two steps are carried out by a single bifunctional enzyme, Met8p. In some bacteria, steps 1-3 are catalysed by a single mult...(incorrect). Enzyme Commission Number: EC 2.1.1.107. CAS No. 125752-76-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1705; uroporphyrinogen-III C-methyltransferase; EC 2.1.1.107; 125752-76-3; uroporphyrinogen methyltransferase; uroporphyrinogen-III methyltransferase; adenosylmethionine-uroporphyrinogen III methyltransferase; S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase; uroporphyrinogen-III methylase; SirA; CysG; CobA [ambiguous - see EC 2.5.1.17] SUMT; uroporphyrin-III C-methyltransferase (incorrect); S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase | |
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