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| Product | Description | |
|---|---|---|
| Fostriecin | The most fully characterised member of a family of phosphate esters of a triene antibiotic; a topoisomerase II inhibitor; selective inhibition of protein phosphatase PP2A. Synonyms: (1E,7E,9E,11E)-3,6,13-trihydroxy-3-methyl-1-(6-oxo-3,6-dihydro-2H-pyran-2-yl)trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate; 2H-Pyran-2-one, 5,6-dihydro-6-[3,6,13-trihydroxy-3-methyl- 4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-, monosodiumsalt. Grades: >95% by HPLC. CAS No. 87810-56-8. Molecular formula: C19H27O9P. Mole weight: 430.39. |  |
| Fostriecin sodium salt | Fostriecin sodium salt is a protein phosphatase types 2A (PP2A) and 4 (PP4) inhibitor (IC50 = 1.5 nM and 3 nM, respectively). It also has an inhibitory effect on topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM). Fostriecin is found in Streptomyces pulveraceous. Uses: Enzyme inhibitors. Synonyms: Fostriecin Sodium; Antibiotic CI 920 sodium salt; (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt. Grades: ≥98% by HPLC. CAS No. 87860-39-7. Molecular formula: C19H26O9PNa. Mole weight: 452.37. | |
| Fostriecin sodium salt from Streptomyces pulveraceus | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Phosphotrienin (Fostriecin, Antibiotic CI 920, Antibiotic CL 1565A, Antibiotic PD 110161, NSC 339638), Sodium Salt | Fostriecin is the most fully characterized member of a family of phosphate esters of a triene antibiotic. The antitumor potential of fostriecin has attracted considerable interest, focused on its mode of action as a topoisomerase II inhibitor. Subsequent research has focused on this metabolite's selective inhibition of protein phosphatase PP2A. Group: Biochemicals. Alternative Names: Fostriecin, Phosphotrienin, Antibiotic CI 920, Antibiotic CL 1565A,Antibiotic PD 110161, NSC 339638. Grades: Highly Purified. CAS No. 87810-56-8. Pack Sizes: 100ug. US Biological Life Sciences. |  Worldwide |
| Sultriecin | Sultriecin is a dominant analogue in the family of triene antibiotic isolated from Streptomyces. It is a phosphate ester of fostriecin and displays potent antifungal and antitumour activity. Synonyms: BU 3285T; (+)-Phostriecin; Phostriecin; (+)-Sultriecin; (5S)-5alpha-Hydroxy-6alpha-[(1E,4S,5S,6S,7Z,9Z,11E)-4-(sodiooxysulfonyloxy)-5-methyl-6-hydroxy-1,7,9,11-heptadecatetraenyl]-5,6-dihydro-2H-pyran-2-one sodium. Grades: >98% by HPLC. CAS No. 131774-59-9. Molecular formula: C23H33NaO8S. Mole weight: 492.56. | |
| Sultriecin (Antibiotic BU 3285T) | Sultriecin is a dominant analogue in a family of sulfate esters of a triene antibiotic isolated from Streptomyces. Despite the structural similarity to fostriecin there is little comparative data to support a common mode of action. Sultriecin is reported to display potent antifungal and antitumor activity. Group: Biochemicals. Alternative Names: Antibiotic BU 3285T. Grades: Highly Purified. CAS No. 131774-59-9. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
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