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Fresolimumab Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-&beta. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab radiolabeled with 89 Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GC1008. CAS No. 948564-73-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99020. MedChemExpress MCE
Fresolimumab Fresolimumab is a human monoclonal antibody targeting transforming growth factor beta (TGF-β). Fresolimumab inhibits the activity of TGF-beta, which may result in the suppression of tumor cell growth, angiogenesis, and migration. Synonyms: GC1008; GC 1008; GC-1008. CAS No. 948564-73-6. BOC Sciences 11

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