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Thesuccinate salt form of Frovatriptan, a carbazole derivative, has been found to be a 5-HT receptor agonist that could be used as an antimigraine agent. Synonyms: (3R)-2,3,4,9-Tetrahydro-3-(methylamino)-1H-carbazole-6-carboxamide butanedioate; 1H-Carbazole-6-carboxamide, 2,3,4,9-tetrahydro-3-(methylamino)-, (3R)-, butanedioate (1:1); Sb-209509ax; Vml 251. Grades: > 95%. CAS No. 158930-09-7. Molecular formula: C18H23N3O5. Mole weight: 361.40.
Frovatriptansuccinate hydrate
Frovatriptan is a selective agonist of the 5-HT1B and 5-HT1D (Kis = 2.51 and 3.98 nM, respectively). Synonyms: SB 209509; VML 251; butanedioic acid, compd. with (R)-2,3,4,9-tetrahydro-3-(methylamino)-1H-carbazole-6-carboxamide, hydrate (1:1:1); R-(+) 3-Methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole monosuccinate monohydrate. Grades: ≥98%. CAS No. 158930-17-7. Molecular formula: C14H17N3O·C4H6O4·H2O. Mole weight: 379.41.
Frovatriptansuccinate hydrate
Frovatriptansuccinate hydrate ((R)-Frovatriptansuccinate hydrate) is a potent, high affinity, selective and orally active 5-HT 1B ( pK 50 of 8.2) and 5-HT 1D receptor agonist. Frovatriptansuccinate hydrate exhibits >10-fold selectivity for 5-HT 1B and 5-HT 1D over 5-HT 1A , 5-HT 1F , and 5-HT 7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H 1 , and α1-adrenoceptor. Frovatriptansuccinate hydrate has the potential for migraine research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Frovatriptansuccinate hydrate; SB 209509 succinate hydrate; VML 251 succinate hydrate. CAS No. 158930-17-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-B1658A.
FrovatriptanSuccinate Monohydrate
Serotonin 5-HT1B/1D receptor agonist. It is a triptan drug for the treatment of migraine headaches. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. Group: Biochemicals. Alternative Names: (3R)-2,3,4,9-Tetrahydro-3-(methylamino)-1H-carbazole-6-carboxamide Butanedioic Acid Monohydrate; Frova; Frovelan; Migard; Miguard. Grades: Highly Purified. CAS No. 158930-17-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
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rac Frovatriptan-d3 Succinate Monohydrate
Serotonin 5-HT1B/1D receptor agonist. It is a triptan drug for the treatment of migraine headaches. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. Group: Biochemicals. Alternative Names: rac-2,3,4,9-Tetrahydro-3-(methyl-d3-amino)-1H-carbazole-6-carboxamide Butanedioic Acid Monohydrate; Frova-d3; Frovelan-d3; Migard-d3; Miguard-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
1-(S)-Hydroxy Frovatriptan is derived from FrovatriptanSuccinate Monohydrate (F768500), which is a serotonin 5-HT1B/1D receptor agonist. It is a triptan drug for the treatment of migraine headaches. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H17N3O2, Molecular Weight: 259.3. US Biological Life Sciences.
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