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| Product | Description | |
|---|---|---|
| fumarate hydratase | Fumarase (or fumarate hydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Group: Enzymes. Synonyms: fumarase; L-malate hydro-lyase; (S)-malate hydro-lyase. Enzyme Commission Number: EC 4.2.1.2. CAS No. 9032-88-6. Fumarase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5013; fumarate hydratase; EC 4.2.1.2; 9032-88-6; fumarase; L-malate hydro-lyase; (S)-malate hydro-lyase. Cat No: EXWM-5013. |  |
| Fumarate Hydratase from Human, Recombinant | Fumarase catalyzes the reversible hydration of fumarate to malate. In its mitochondrial form, fumarate is involved in the Krebs Cycle, while the cytosolic form is involved in amino acid metabolism. Group: Enzymes. Synonyms: EC 4. 2. 1. 2; fumarase; L-malate hydro-lyase; (S)-malate hydro-lyase; 9032-88-6; MCL; LRCC; HLRCC; MCUL1; FH. Enzyme Commission Number: EC 4. 2. 1. 2. Purity: >95% by SDS-PAGE analysis. Mole weight: 50.2 kDa. Activity: >25 unit/mg. Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. Form: Sterile filtered colorless solution. Source: E. coli. Species: Human. EC 4. 2. 1. 2; fumarase; L-malate hydro-lyase; (S)-malate hydro-lyase; 9032-88-6; MCL; LRCC; HLRCC; MCUL1; FH; Fumarate hydratase. Cat No: NATE-1777. | |
| Fumarate hydratase-IN-1 | Fumarate hydratase-IN-1, an enzyme of the TCA cycle, identified as the principal pharmacological target. CAS No. 1644060-37-6. Molecular formula: C27H30N2O4. Mole weight: 446.54. |  |
| R162 | R162 is a potent, selective inhibitor of glutamate dehydrogenase 1 (GDH1) (Ki = 28.6 μM), with anti-cancer properties. It does not inhibit the activity of other NADPH enzymes such as 6-phosphogluconate dehydrogenase and fumarate hydratase. Synonyms: R 162; R-162; 2-allyl-1-hydroxy-anthraquinone; 2-allyl-1-hydroxyanthra-9,10-quinone. CAS No. 64302-87-0. Molecular formula: C17H12O3. Mole weight: 264.28. | |
| (S)-2-methylmalate dehydratase | Also hydrates fumarate to (S)-malate. Group: Enzymes. Synonyms: mesaconate hydratase; (+)-citramalate hydro-lyase; L-citramalate hydrolase; citramalate dehydratase; (+)-citramalic hydro-lyase; mesaconate mesaconase; mesaconase; (S)-2-methylmalate hydro-lyase. Enzyme Commission Number: EC 4.2.1.34. CAS No. 9027-94-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5025; (S)-2-methylmalate dehydratase; EC 4.2.1.34; 9027-94-5; mesaconate hydratase; (+)-citramalate hydro-lyase; L-citramalate hydrolase; citramalate dehydratase; (+)-citramalic hydro-lyase; mesaconate mesaconase; mesaconase; (S)-2-methylmalate hydro-lyase. Cat No: EXWM-5025. | |
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