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Gallein Gallein. Group: Biochemicals. Grades: Purified. CAS No. 2103-64-2. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 5
Worldwide
Gallein Gallein is an inhibitor of G protein βγ subunit-dependent signaling leading to the inhibition of neutrophil chemotaxis and inflammation. It blocks PI 3-kinase and Rac1 activation in HL60 cells. Synonyms: 3',4',5',6'-Tetrahydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one; Alizarin violet; Pyrogallolphthalein; C.I. Mordant Violet 25; 4,5-Dihydroxyfluorescein. Grades: ≥97%. CAS No. 2103-64-2. Molecular formula: C20H12O7. Mole weight: 364.31. BOC Sciences 9
OXE-R-Gbg Coupling Modulator, Gue1654 (7- (Methylthio) -2- ( (2, 2-diphenylacetyl) amino) benzo[1, 2-d: 4, 3-d’]bisthiazole, N-(7-(Methylsulfanyl)[1, 3]thiazolo[4, 5-g][1, 3]benzothiazol-2-yl)-2, 2-diphenylacetamide) A membrane-p’ermeant amidobenzobisthiazolo compound that modulates OXE-R-G-beta-gamma coupling upon receptor stimulation via direct OXE-R interaction, without affecting preexisting OXE-R-Galpha-beta interaction. Selectively inhibits OXE-R-G-beta-gamma coupling-mediated, but not OXE-R-G-alpha-mediated, downstream cellular signalings (Effective Conc. 1 to 30uM), displaying no inhibitory activity against cellular functions mediated by G-alpha or G-beta-gamma when coupled to other GPCRs. Comparing to Gallein, Gue1654 does not exert its activity via direct G-beta-gamma interaction. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??N?OS?. US Biological Life Sciences. USBiological 4
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