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Gambogenic Acid is a natural compound isolated from Garcinia hanburyi Hook. f. It shows anticancer activity. Grades: 98%. CAS No. 173932-75-7. Molecular formula: C38H46O8. Mole weight: 630.8.
Gambogenic Acid
Gambogenic acid is an active ingredient in gamboge, with anticancer activity. Gambogenic acid acts as an effective inhibitor of EZH2, specifically and covalently binds to Cys668 within the EZH2-SET domain, and induces EZH2 ubiquitination. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (2Z)-4-[(1R,3aS,5S,12aS)-9-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-3a,4,5,7-tetrahydro-8,10-dihydroxy-3,3-dimethyl-11-(3-methyl-2-buten-1-yl)-7,13-dioxo-1,5-methano-1H,3H-furo[3,4-d]xanthen-1-yl]-2-methyl-2-butenoic acid. Product Category: Inhibitors. Appearance: Brownish red powder. CAS No. 173932-75-7. Molecular formula: C38H46O8. Mole weight: 630.77. Purity: 0.98. IUPACName: (Z)-4-[(1S,2S,13S,15R)-7-[(2E)-3,7-dimethylocta-2,6-dienyl]-6,8-dihydroxy-17,17-dimethyl-5-(3-methylbut-2-enyl)-10,14-dioxo-3,16-dioxapentacyclo[11.4.1.02,11.02,15.04,9]octadeca-4,6,8,11-tetraen-15-yl]-2-methylbut-2-enoic acid. Canonical SMILES: CC(=CCC/C(=C/CC1=C(C(=C2C(=C1O)C(=O)C3=C[C@@H]4C[C@@H]5[C@@]3(O2)[C@](C4=O)(OC5(C)C)C/C=C(/C)\C(=O)O)CC=C(C)C)O)/C)C. Density: 1.27±0.1 g/ml. Product ID: ACM173932757. Alfa Chemistry ISO 9001:2015 Certified.
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