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| Product | Description | |
|---|---|---|
| Ganglioside GM3 | Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 124579-05-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-114456. |  |
| GM3-Ganglioside | GM3-Ganglioside, a renowned biomedical compound, is an exceptional therapeutic agent employed for managing debilitating neurodegenerative conditions, prominently encompassing Alzheimer's disease and Parkinson's disease. Its inherent proficiency in preserving neuronal coherence and functionality renders it indispensable in clinical practice. Synonyms: aNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer; Ganglioside GM3; Ganglioside M3; Gangliosides, GM3; GLac1; GM3; Hematoside; Monosialodihexosylganglioside; Sialosyllactosylceramide. CAS No. 54827-14-4. |  |
| GM3-Ganglioside labelled by NBD | GM3-Ganglioside labelled by NBD is a specialized GM3-Ganglioside molecule, known for its facile integration with NBD fluorescent probe. Its wide-ranging application encompasses unfathomable diseases, including cancer and neurodegenerative disorders. Synonyms: N-(Acetyl-a-D-neuraminic acid)-(2->3)-O-b-D-galactopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->1)-(2S,3R,4E)-2-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)aminooctanamido-4-octadecene-1,3-diol ammonium salt; aNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer linked 7-nitrobenz-2-oxa-1,3-diazole. Molecular formula: C55H90N6O24 H3N. Mole weight: 1236.36. | |
| GM3-Ganglioside labelled by NBD ammonium | GM3-Ganglioside labelled by NBD ammonium is a vital tool in the biomedical industry used for researching and diagnosing various diseases. This product plays a crucial role in studying and understanding the targeting and metabolism of GM3-Ganglioside, a glycosphingolipid involved in neurological disorders and cancer progression. Its NBD ammonium label allows for fluorescence-based detection and visualization in biological systems, enabling accurate analysis and potential therapeutic advancements. Synonyms: (N-Acetyl-a-D-neuraminic acid)-(2->3)-O-b-D-galactopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->1)-(2S,3R,4E)-2-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)aminooctanamido-4-octadecene-1,3-diol ammonium salt; aNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer linked 7-nitrobenz-2-oxa-1,3-diazole ammonium salt. Grade: 95%. Molecular formula: C55H90N6O24.NH3. Mole weight: 1236.36. | |
| GM3NeuGc-Ganglioside | GM3NeuGc-Ganglioside is an indispensable compound, catering to studying cancer. It operates as a remarkable ganglioside variant responsible for pivotal cellular communication and immune system activation. Synonyms: a-Neu5Gc-(2-3)-b-Gal-(1-4)-b-Glc-(1-1)-Cer. | |
| α-N-acetylneuraminate α-2,8-sialyltransferase | Gangliosides act as acceptors. Group: Enzymes. Synonyms: cytidine monophosphoacetylneuraminate-ganglioside GM3; α-2,8-sialyltransferase; ganglioside GD3 synthase; ganglioside GD3 synthetase sialyltransferase; CMP-NeuAc:LM1(α2-8) sialyltranferase; GD3 synthase; SAT-2. Enzyme Commission Number: EC 2.4.99.8. CAS No. 67339-00-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2712; α-N-acetylneuraminate α-2,8-sialyltransferase; EC 2.4.99.8; 67339-00-8; cytidine monophosphoacetylneuraminate-ganglioside GM3; α-2,8-sialyltransferase; ganglioside GD3 synthase; ganglioside GD3 synthetase sialyltransferase; CMP-NeuAc:LM1(α2-8) sialyltranferase; GD3 synthase; SAT-2. Cat No: EXWM-2712. |  |
| C11 TopFluor® GM3 Ammonium salt | C11 TopFluor® GM3 Ammonium salt - a highly pure, fluorescent lipid probe that delves into the intricacies of ganglioside metabolism within biological samples. This remarkable probe is not just limited to that though; it can alight on GM3 gangliosides within cells that are involved in disruptive lipid-related diseases like neurodegeneration, inherited metabolic disorders and cancer. That's not all - TopFluor® GM3's exceptional structural and fluorescence properties place it on a pedestal as an invaluable tool for scrutinizing lipid membrane dynamics and signal transduction pathways with great precision. Synonyms: C11 TopFluor GM3 Ganglioside (ammonium salt); Borate(1-), [N-[(1S,2R,3E)-1-[[[O-(N-acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-λ-(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)-3,5-dimethyl-1H-pyrrole-2-dodecanamidato(2-)-κN1]difluoro-, ammonium (1:1), (T-4)-; (T-4)-[N-[(1S,2R,3E)-1-[[[O-(N-Acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-λ-(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)-3,5-dimethyl-1H-pyrrole-2-dodecanamidato(2-)-κN1]difluoroborate(1-) ammonium salt. CAS No. 2260795-48-8. Molecular formula: C65H110BF2N5O21. Mole weight: 1346.40. | |
| globotriaosylceramide 3-β-N-acetylgalactosaminyltransferase | Globoside is a neutral glycosphingolipid in human erythrocytes and has blood-group-P-antigen activity. The enzyme requires a divalent cation for activity, with Mn2+ required for maximal activity. UDP-GalNAc is the only sugar donor that is used efficiently by the enzyme: UDP-Gal and UDP-GlcNAc result in very low enzyme activity. Lactosylceramide, globoside and gangliosides GM3 and GD3 are not substrates. For explanation of the superscripted '3' in the systematic name, see GL-5.3.4. Group: Enzymes. Synonyms: uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase; globoside synthetase; UDP-N-acetylgalactosamine: globotriaosylceramide β-3-N-acetylgalactosaminyltransferase; galactosylgalactosylglucosylceramide β-D-acetylgalactosaminyltransferase; UDP-N-acetylgalactosamine: globotriaosylceramide β1,3-N-acetylgalactosaminyltrans. Enzyme Commission Number: EC 2.4.1.79. CAS No. 62213-46-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2619; globotriaosylceramide 3-β-N-acetylgalactosaminyltransferase; EC 2.4.1.79; 62213-46-1; uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase; globoside synthetase; UDP-N-acetylgala. | |
| lactosylceramide α-2,3-sialyltransferase | Lactose cannot act as acceptor. Group: Enzymes. Synonyms: cytidine monophosphoacetylneuraminate-lactosylceramide α2,3- sialyltransferase; CMP-acetylneuraminate-lactosylceramide-sialyltransferase; CMP-acetylneuraminic acid:lactosylceramide sialyltransferase; CMP-sialic acid:lactosylceramide-sialyltransferase; cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase; ganglioside GM3 synthetase; GM3 synthase; GM3 synthetase; SAT. Enzyme Commission Number: EC 2.4.99.9. CAS No. 125752-90-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2713; lactosylceramide α-2,3-sialyltransferase; EC 2.4.99.9; 125752-90-1; cytidine monophosphoacetylneuraminate-lactosylceramide α2,3- sialyltransferase; CMP-acetylneuraminate-lactosylceramide-sialyltransferase; CMP-acetylneuraminic acid:lactosylceramide sialyltransferase; CMP-sialic acid:lactosylceramide-sialyltransferase; cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase; ganglioside GM3 synthetase; GM3 synthase; GM3 synthetase; SAT 1; CMP-N-acetylneuraminate:lactosylceramide α-2,3-N-acetylneuraminyltransferase; CMP-N-acetylneuraminate:β-D-galactosyl-(1?4)-β-D-glucosyl(1<->1)ceramide α-(2?3)-N-acetylneuraminyltransferase. Cat No: EXWM-2713. | |
| (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase | This enzyme catalyses the formation of the gangliosides (i.e. sialic-acid-containing glycosphingolipids) GM2, GD2 and SM2 from GM3, GD3 and SM3, respectively. Asialo-GM3 and lactosylceramide are also substrates, but glycoproteins and oligosaccharides are not substrates. Group: Enzymes. Synonyms: uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase; ganglioside GM2 synthase; ganglioside GM3 acetylgalactosaminyltransferase; GM2 synthase; UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase; UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-α-neuraminyl)-(2?3)-O-β-D-galactopyranosyl-(1?4)-β-D-glucopyranosyl]-ceramide 1,4-β-N-acetyl-D-galactosaminyltransferase acetylgalactosa. Enzyme Commission Number: EC 2.4.1.92. CAS No. 67338-98-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2632; (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase; EC 2.4.1.92; 67338-98-1; uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase; ganglioside GM2 synthase; ganglioside GM3 acetylgalactosaminyltransferase; GM2 synthase; UDP acetylgalactosamine-(N-acetylneuraminyl)-D-gal. | |
| Native Bovine Lysogangliosides | Lyso-gangliosides are prepared by removing glycolipid enzymatically from natural gangliosides. They can be used to analyze various cell function, such as cell proliferation, differentiation, apoptosis, signal transduction, etc. It can also be used as a material of ganglioside derivatives in RI labeling, fluorescence labeling, immobilization since they have free amino group in sphingosine. Group: Enzymes. Synonyms: Lyso-gangliosides; Lyso-GM3; Lysogangliosides. Purity: Greater than 95% by TLC. Lysogangliosides. Storage: -20°C. Form: Lyophilized. Source: Bovine milk ganglioside GM3. Species: Bovine. Lyso-gangliosides; Lyso-GM3; Lysogangliosides. Cat No: NATE-0870. | |
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