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Gap 26. Group: Biochemicals. Grades: Purified. CAS No. 197250-15-0. Pack Sizes: 1mg. US Biological Life Sciences.
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Gap 26
Gap 26 is a connexin mimetic peptide, composed of residue numbers 63-75 of the first extracellular loop of connexin 43 (gap junction blocker), containing the SHVR amino acid motif [1]. Uses: Scientific research. Group: Peptides. CAS No. 197250-15-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1082.
Gap 26
Gap 26 is a gap junction blocker which is corresponding to residues 63 - 75 of connexin 43. Gap 26 was shown to attenuate rhythmic contractile activity of rabbit arterial smooth muscle (IC50 = 28.4 μM). It also inhibits IP3-induced ATP release but does not inhibit gap junctional coupling in endothelial cells. Synonyms: H-Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg-OH; L-valyl-L-cysteinyl-L-tyrosyl-L-alpha-aspartyl-L-lysyl-L-seryl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-seryl-L-histidyl-L-valyl-L-arginine; Gap26; Gap-26; Connexin 43 (63-75) (human, bovine, mouse, rat); Gap Junction α-1 Protein (63-75). Grades: 98%. CAS No. 197250-15-0. Molecular formula: C70H107N19O19S. Mole weight: 1550.78.
Alfa Chemistry offers high-purity 4-(Dicyanomethylene)-2-methyl-6-[2-(2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizin-9-yl)vinyl]-4H-pyran products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: The dcm dyes are useful for laser oscillation and a red dopant for an organic light-emitting diode device. this dye is a low band gap material with good efficiency and long lifetime. Group: Organic light-emitting diode (oled) materials. Alternative Names: DCM 2 4-(Dicyanomethylene)-2-[2-(julolidin-9-yl)vinyl]-6-methyl-4H-pyran. CAS No. 51325-95-2. Product ID: 2-[2-[(E)-2-(1-azatricyclo[7.3.1.05,13]trideca-5,7,9(13)-trien-7-yl)ethenyl]-6-methylpyran-4-ylidene]propanedinitrile. Molecular formula: 355.44. Mole weight: C23H21N3O. CC1=CC (=C (C#N)C#N)C=C (O1)C=CC2=CC3=C4C (=C2)CCCN4CCC3. InChI=1S/C23H21N3O/c1-16-10-20 (21 (14-24) 15-25) 13-22 (27-16) 7-6-17-11-18-4-2-8-26-9-3-5-19 (12-17) 23 (18) 26/h6-7, 10-13H, 2-5, 8-9H2, 1H3/b7-6+. ZNJRONVKWRHYBF-VOTSOKGWSA-N. >97.0%(HPLC)(N).
D131 dye
D131 dye is an indoline based organic dye that has a large band-gap and can be used as a sensitizer in organic electronics. It shows a power conversion efficiency of 5.6% and can enhance photo-excitation of the electrochemical devices. Uses: D131 can be used in dye sensitized solar cells (dsscs) as a photosensitizer with high charge mobility and absorption coefficient. Group: Organic solar cell (opv) materials. Alternative Names: 2-Cyano-3-[4-[4-(2,2-diphenylethenyl)phenyl]-1,2,3,3a,4,8b-hexahydrocyclopent[b]indol-7-yl]-2-propenoic acid. Pack Sizes: 200 mg in glass insert. Molecular formula: 508.61. OC (/C (C#N) =C/C (C=C1) =CC2=C1N (C3=CC=C (C=C (C4=CC=CC=C4) C5=CC=CC=C5) C=C3) C6C2CCC6) =O. 1S/C35H28N2O2/c36-23-28 (35 (38) 39) 20-25-16-19-34-32 (22-25) 30-12-7-13-33 (30) 37 (34) 29-17-14-24 (15-18-29) 21-31 (26-8-3-1-4-9-26) 27-10-5-2-6-11-27/h1-6, 8-11, 14-22, 30, 33H, 7, 12-13H2, (H, 38, 39) /b28-20+, GOTRYMLNXIJMCB-VFCFBJKWSA-N. GOTRYMLNXIJMCB-VFCFBJKWSA-N.
Gap Junction Enhancer, PQ7
A cell-permeable quinoline derived compound with low toxicity that enhances gap junctional activity by about 16-fold (at ~500nM) in T47D breast cancer cells and thereby potentiates the effect of chemotherapeutic agents. Blocks T47D cell colony formation (IC50 = 100nM) and reduce the growth of T47D xenograft tumors by 100% in Nu/Nu mice. Increases caspase-3, - 8, and -9 expression by 1.6, 2.8, and 3.8-fold, respectively to induce apoptotic cell death. Can work synergistically with cisplatin to reduce or totally eliminate tumor growth. Increases the expression of connexins 26, 32, and 43 to allow more efficient trafficking of cisplatin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N2O?, Primary Target IC50: 100nM. US Biological Life Sciences.