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| Product | Description | |
|---|---|---|
| GKA 50 | GKA 50. Group: Biochemicals. Grades: Purified. CAS No. 851884-87-2. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| GKA 50 | GKA 50 is a potent glucokinase activator (EC50 = 33 nM). It causes a decrease in plasma glucose levels in diabetic rats and an increase of insulin release from mouse islets of Langerhans. GKA 50 was shown to promote proliferation and prevent apoptosis in rat pancreatic insulinoma-1 beta cell. Synonyms: GKA 50; GKA50; GKA-50; 6-[[3-[(1S)-2-Methoxy-1-methylethoxy]-5-[(1S)-1-methyl-2-phenylethoxy]benzoyl]amino-3-pyridinecarboxylic acid. Grades: ≥98% by HPLC. CAS No. 851884-87-2. Molecular formula: C26H28N2O6. Mole weight: 464.51. |  |
| methyl 3-(benzyloxy)-5-hydroxybenzoate | An intermediate in the synthesis of the glucokinase activator GKA 50. Synonyms: 3-Benzyloxy-5-hydroxy-benzoic Acid Methyl Ester. CAS No. 54915-31-0. Molecular formula: C15H14O4. Mole weight: 258.27. | |
| Nerigliatin | Nerigliatin (PF-04937319) is a orally active glucokinase activator ( GKA ) with EC 50 value of 154.4 μM. Nerigliatin maintains glucose-lowering efficacy. Nerigliatin causes peripheral nerve degeneration. Nerigliatin can be used in type 2 diabetes research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-04937319. CAS No. 1245603-92-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108328. |  |
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