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| Product | Description | |
|---|---|---|
| Glaucine | Glaucine (O,O-Dimethylisoboldine) is an alkaloid extracted from Glaucium flavum that possesses various activities, including cough relief, bronchodilation, anti-inflammatory effects, analgesia, antipyretic properties, and anticancer effects. Glaucine acts as a selective and orally active inhibitor of phosphodiesterase 4 ( PDE4 ), with a K i of 3.4 μM in human bronchial tissues and polymorphonuclear leukocytes. Glaucine induces relaxation of human isolated bronchi by antagonizing calcium channels. Additionally, Glaucine inhibits the activation of NF-κB , leading to a reduction in the expression of the MMP-9 gene, thereby suppressing the migration and invasion of breast cancer cells. Therefore, Glaucine holds potential for research in asthma and breast cancer [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: O,O-Dimethylisoboldine; S-(+)-Glaucine; NSC 34396. CAS No. 475-81-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N3945. |  |
| Glaucine | Glaucine (O,O-Dimethylisoboldine) is an alkaloid isolated from Glaucium flavum with antitussive, bronchodilation and anti-inflammatory properties. Glaucine is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor with Kis of 3.4 μM in human bronchus and polymorphonuclear leukocytes. Glaucine is also a non-selective α-adrenoceptor antagonist, a Ca2+ entry blocker, and a weak dopamine D1 and D2 receptor antagonist. Glaucine has antioxidative and antiviral activities. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,2,9,10-Tetramethoxy-6a-alpha-aporphine. Product Category: Inhibitors. CAS No. 475-81-0. Molecular formula: C21H25NO4. Mole weight: 355.4. Purity: 95%+. Product ID: ACM475810. Alfa Chemistry ISO 9001:2015 Certified. |  |
| (R)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline | (R)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (R)-5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline;(6aR)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline. Product Category: Heterocyclic Organic Compound. CAS No. 38325-02-9. Molecular formula: C21H25NO4. Mole weight: 355.4275. Product ID: ACM38325029. Alfa Chemistry ISO 9001:2015 Certified. Categories: l-Glaucine. | |
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