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| Product | Description | |
|---|---|---|
| Glesatinib | Glasatinib (MGCD265) is a dual MET/SMO inhibitor. Glesatinib is a small molecule, multi-target tyrosine kinase inhibitor with potential anti-tumor activity, which can antagonize P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC). Synonyms: MGCD-265; MGCD 265; MGCD265. Grades: ≥98% by HPLC. CAS No. 936694-12-1. Molecular formula: C31H27F2N5O3S2. Mole weight: 619.7. |  |
| Glesatinib hydrochloride | Glesatinib hydrochloride (MGCD265 hydrochloride) is an orally active, potent MET/SMO dual inhibitor. Glesatinib hydrochloride, a tyrosine kinase inhibitor, antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGCD265 hydrochloride. CAS No. 1123838-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19642A. |  |
| Glesatinib hydrochloride | The hydrochloride salt form of Glesatinib, an inhibitor of tyrosine kinase, could be effectively targeting tumors that are driving to grow through MET and AXL receptor. It seems to be more common in non-small cell lung cancer and it is still under Phase I. Uses: The hydrochloride salt form of glesatinib could be effectively targeting tumors that are driving to grow through met and axl receptor. Synonyms: MGCD265 hydrochloride; MGCD-265 hydrochloride; MGCD 265 hydrochloride. Grades: 98%. CAS No. 1123838-51-6. Molecular formula: C31H27ClF2N5O3S2X. Mole weight: 655.16. | |
| MGCD-265 | MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively and also inhibits Ron and Tie2. Synonyms: MGCD-265; MGCD 265; MGCD265; MGCD-265-analog; MGCD 265-analog; MGCD265-analog. Glesatinib-analog. Grades: >98%. CAS No. 875337-44-3. Molecular formula: C26H20FN5O2S2. Mole weight: 517.60. | |
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