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Guanosine 5'-monophosphate has been found to be useful in studies of modulation of glutamatergic neurotransmission. Synonyms: Guanosine-5'-monophosphate; 5'-Guanylic Acid. Grades: ≥ 95 % by HPLC. Molecular formula: C10H14N5O8P. Mole weight: 363.22.
GMPαS
GMPαS, a synthesized protein of biotechnological application, is utilized in the biomedical sector for the purpose of investigation into the sprawling domain of inflammatory bowel disease (IBD). This recombinant compound fosters an effective anti-inflammatory response via the suppression of cytokine production associated with the onset of IBD. Additionally, GMPαS's therapeutic possibilities are gaining increasing scientific traction as a potential target for treating a gamut of autoimmune and underlying inflammatory maladies. Synonyms: Guanosine-5'-(α-thio)-monophosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C10H14N5O7PS (free acid). Mole weight: 379.28 (free acid).
GMP reductase
It converts nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and maintains intracellular balance of A and G nucleotides. In melanocytic cells, GMP reductase gene expression may be regulated by MITF. Group: Enzymes. Synonyms: guanosine 5'-monophosphate reductase; NADPH:GMP oxidoreductase (deaminating); guanosine monophosphate reductase; guanylate reductase; NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating); guanosine 5'-phosphate reductase. Enzyme Commission Number: EC 1.7.1.7. CAS No. 9029-32-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1614; GMP reductase; EC 1.7.1.7; 9029-32-7; guanosine 5'-monophosphate reductase; NADPH:GMP oxidoreductase (deaminating); guanosine monophosphate reductase; guanylate reductase; NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating); guanosine 5'-phosphate reductase. Cat No: EXWM-1614.
GMP synthase (glutamine-hydrolysing)
Involved in the de novo biosynthesis of guanosine nucleotides. An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain. The enzyme can catalyse the second reaction alone in the presence of ammonia. Group: Enzymes. Synonyms: GMP synthetase (glutamine-hydrolysing); guanylate synthetase (glutamine-hydrolyzing); guanosine monophosphate synthetase (glutamine-hydrolyzing); xanthosine 5'-phosphate amidotransferase; guanosine 5'-monophosphate synthetase. Enzyme Commission Number: EC 6.3.5.2. CAS No. 37318-71-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5805; GMP synthase (glutamine-hydrolysing); EC 6.3.5.2; 37318-71-1; GMP synthetase (glutamine-hydrolysing); guanylate synthetase (glutamine-hydrolyzing); guanosine monophosphate synthetase (glutamine-hydrolyzing); xanthosine 5'-phosphate amidotransferase; guanosine 5'-monophosphate synthetase. Cat No: EXWM-5805.
2'-/3'-AEC-5'-GMP
2'-/3'-AEC-5'-GMP is an analogue of guanosine-5'-O-monophosphate used as a ligand for immobilization and coupling of diffferent dyes and labels. Synonyms: 2'- / 3'- O- (2- Aminoethylcarbamoyl)guanosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97 % by HPLC. Molecular formula: C13H20N7O9P (free acid). Mole weight: 449.3 (free acid).
2'-/3'-AHC-5'-GMP
2'-/3'-AHC-5'-GMP is an analogue of guanosine-5'-O-monophosphate used as a ligand for immobilization and for coupling of different dyes and labels. Synonyms: 2'- / 3'- O- (6- Aminohexylcarbamoyl)guanosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97 % by HPLC. Molecular formula: C17H28N7O9P (free acid). Mole weight: 505.4 (free acid).
2'-/3'-TAMRA-AEC-5'-GMP
2'-/3'-TAMRA-AEC-5'-GMP is a fluorescent analogue of guanosine-5'-monophosphate (λexc555 nm; λem580 nm). Synonyms: 2'- / 3'- O- (6- [Tetramethylrhodaminyl] aminoethylcarbamoyl) guanosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H40N9O13P (free acid). Mole weight: 861.8 (free acid).
2'-GMP
2'-GMP is a metabolite of guanosine-2',3'-cyclic monophosphate. Synonyms: Guanosine- 2'- O- monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 130-50-7. Molecular formula: C10H14N5O8P (free acid). Mole weight: 363.2 (free acid).
3',5'-cyclic-GMP phosphodiesterase
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. Group: Enzymes. Synonyms: guanosine cyclic 3',5'-phosphate phosphodiesterase; cyclic GMP phosphodiesterase; cyclic 3',5'-GMP phosphodiesterase; cyclic guanosine 3',5'-monophosphate phosphodiesterase; cyclic guanosine 3',5'-phosphate phosphodiesterase; cGMP phosphodiesterase; cGMP-PDE. Enzyme Commission Number: EC 3.1.4.35. CAS No. 9068-52-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3719; 3',5'-cyclic-GMP phosphodiesterase; EC 3.1.4.35; 9068-52-4; guanosine cyclic 3',5'-phosphate phosphodiesterase; cyclic GMP phosphodiesterase; cyclic 3',5'-GMP phosphodiesterase; cyclic guanosine 3',5'-monophosphate phosphodiesterase; cyclic guanosine 3',5'-phosphate phosphodiesterase; cGMP phosphodiesterase; cGMP-PDE. Cat No: EXWM-3719.
3'-GMP
3'-GMP is a metabolite of guanosine-2',3'-cyclic monophosphate. Synonyms: Guanosine- 3'- O- monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 6027-83-4. Molecular formula: C10H14N5O8P (free acid). Mole weight: 363.2 (free acid).
6-Methylthio-GMP
6-Methylthio-GMP, a highly potent nucleotide analog, exhibits remarkable efficacy against diverse viral infections and several cancers. This promising molecule significantly interferes with DNA synthesis, thereby repressing tumor growth and inhibiting viral replication. Moreover, cutting-edge research indicates its potential for treating inflammation. Synonyms: 6-Methylthioguanosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H16N5O7PS (free acid). Mole weight: 393.31 (free acid).
6-Thio-GMP
6-Thio-GMP, a bioactive compound employed for biomedical research, demonstrates inhibitory effects on numerous tumors, rendering it a prospective therapeutic intervention for leukemia and lymphoma. Moreover, it displays antiviral capability as validated by its potency to inhibit replication of viruses such as Ebola virus. Synonyms: 6-Thio-guanosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 15867-02-4. Molecular formula: C10H14N5O7PS (free acid). Mole weight: 379.28 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-655
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-655, a fluorescent probe that selectively interacts with cyclic GMP, offers a unique opportunity to gain insights into the spatiotemporal regulation of this crucial second messenger in living cells. By illuminating the intricacies of cyclic GMP signaling, this probe promises to unlock the secrets of a wide range of diseases, from cardiovascular disorders to cancer. Witness the power of precision science with this cutting-edge technology. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 655, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 655 (free acid). Mole weight: 968.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-665
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-665 is a fluorescent-labeled nucleotide used in biomedicine to study guanosine cyclic monophosphate (cGMP)-related signaling pathways. It has been used in studies looking at nitric oxide (NO) signaling and the cyclic GMP-protein kinase G (PKG) pathway, which are involved in regulating smooth muscle relaxation. Additionally, it has potential therapeutic applications in treating cardiovascular diseases and pulmonary hypertension. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 665. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 665 (free acid). Mole weight: 1063.39 (free acid).
8-[(6-Amino)hexyl]-amino-GMP
8-[(6-Amino)hexyl]-amino-GMP is a remarkable bioactive compound lauded in the biomedical industry, acting as an inhibitor. It diligently obstructs disease progression by intricately targeting specialized biochemical pathways. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P (free acid). Mole weight: 477.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - 5/6-TAMRA
8-[(6-Amino)hexyl]-amino-GMP - 5/6-TAMRA is an esteemed fluorescent probe which specializes in the detection and analysis of cell signaling pathways related to G proteins and cyclic nucleotides. Deployed across a range of biomedical industries for research on cancer, cardiovascular diseases, and neurological disorders, this fantastic product is the ideal instrument for unraveling the mysteries of cellular communication. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with 5/6-TAMRA. Grades: ≥ 95% by HPLC. Molecular formula: C41H48N9O16P (free acid). Mole weight: 889.85 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - 5-FAM
8-[(6-Amino)hexyl]-amino-GMP - 5-FAM is a nucleotide analog, profoundly contributing to DNA and RNA research and development, replication and repair processes. Moreover, its pivotal role in drug discovery research resonates strongly, facilitating the identification and validation of prospective drug targets pertaining to cancer, infectious diseases and genetic disorders. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with 5 FAM, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H38N7O14P (free acid). Mole weight: 835.72 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - 6-FAM
8-[(6-Amino)hexyl]-amino-GMP - 6-FAM, a fluorescently-labeled nucleotide analog, is an extensively employed molecule in the field of biomedicine for observing DNA replication and repair, along with mRNA transcription. Furthermore, this molecule serves as an essential diagnostic tool for diseases like cancer and viral infections. Its versatile applications in various fields render it a highly sought-after compound. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with 6 FAM, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H38N7O14P (free acid). Mole weight: 835.72 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - 6-JOE
8-[(6-Amino)hexyl]-amino-GMP - 6-JOE is a fundamental recompound in the biomedical realm, profoundly facilitates the fluorescent labeling and imaging of nucleic acids. Its efficacious design specifically engenders potent affinity towards nucleic acids, thereby augmenting the inquiry of DNA or RNA. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with 6-JOE, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C39H40Cl2N7O16P (free acid). Mole weight: 963.16 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - 6-ROX
8-[(6-Amino)hexyl]-amino-GMP - 6-ROX is a remarkable fluorescent dye. Its versatility and widespread adoption stem from its prominent attributes in terms of labeling and detection, particularly within nucleic acid investigations. This indispensable compound facilitates the visualization of intricate cellular mechanisms, encompassing vital phenomena like DNA enhancement, replication and gene expression. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with 6-ROX. Grades: ≥ 95% by HPLC. Molecular formula: C49H56N9O12P (free acid). Mole weight: 994.01 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-390
8-[(6-Amino)hexyl]-amino-GMP - ATTO-390 is a powerful and versatile fluorescent probe that shines a light on the molecular biology field. This scientific breakthrough is a crucial tool for biomedical research as it enables sensitive detection and visualization of RNA in cells and tissues. Not just limited to research, it also has diagnostic capabilities for varied diseases like cancer and viral infections. With its unique fluorescent properties, it opens new doors for clinical diagnostics of RNA in molecular biology. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 390, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C36H51N8O11P (free acid). Mole weight: 802.82 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-425
8-[(6-Amino)hexyl]-amino-GMP - ATTO-425 is a versatile fluorescent dye that finds its uses in diverse applications ranging from studying cell signaling pathways to DNA sequencing and monitoring changes in intracellular calcium levels. Its high brightness and photostability has made it the preferred choice in the industry for labeling biomolecules in biomedical research. This product is a potent tool that facilitates scientific research and experimental inquiries. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 425, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H53N8O13P (free acid). Mole weight: 860.85 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-465
8-[(6-Amino)hexyl]-amino-GMP - ATTO-465 is a fluorescent labeling reagent widely used in biomedical research for labeling and visualizing nucleotides and proteins in living cells. It can be applied in various techniques such as FRET, super-resolution microscopy and live-cell imaging. It could be paired with multiple biomolecules for detecting diseases in early stages or designing new drugs for treating various diseases. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 465. Grades: ≥ 95% by HPLC. Molecular formula: C33H43N10O9P (free acid). Mole weight: 754.73 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-488
8-[(6-Amino)hexyl]-amino-GMP - ATTO-488 is a fluorescent dye conjugate commonly used in biomedical research exhibiting green fluorescence upon excitation, making it suitable for various applications such as cellular imaging, flow cytometry and fluorescence microscopy. This compound enables visualization and tracking of cellular processes and structures, contributing to the understanding of compound interactions, molecular pathways and disease mechanisms. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 488, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C41H49N10O17PS2 (free acid). Mole weight: 1048.25 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-495
8-[(6-Amino)hexyl]-amino-GMP - ATTO-495, an essential fluorescent probe utilized in biomedical research, has the potential to revolutionize the field of protein, nucleic acids, and small molecule labeling and visualization. Thus, it is a valuable tool, especially in drug discovery and the study of cancer and neurodegenerative disorders. Its high sensitivity and specificity offer tremendous potential to improve biomedicine and further our understanding of complex medical conditions. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 740, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H51N10O9P (free acid). Mole weight: 810.84 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-532
8-[(6-Amino)hexyl]-amino-GMP - ATTO-532 is a fluorescently labeled guanosine monophosphate, commonly used as a probe in biomedicine studies. It displays high specificity to viral DNA and RNA, making it a valuable tool in the diagnosis and treatment of viral diseases. Additionally, it has been utilized as a means to monitor the kinetics of drug transporter activity in vitro. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 532, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C45H57N10O17PS2 (free acid). Mole weight: 1104.31 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-540Q
8-[(6-Amino)hexyl]-amino-GMP - ATTO-540Q is a fluorescent probe widely used in targeting and binding to certain proteins and molecules associated with diseases such as cancer, allowing for their visualization and analysis. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 540Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 540Q (free acid). Mole weight: 1017.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-550
ATTO-550 - 8-[(6-Amino)hexyl]-amino-GMP is a highly sophisticated fluorescent probe that has been meticulously engineered to gauge cyclic GMP levels in the body. Its immense versatility and potency render it as indispensable in research for assessing G-protein coupled receptors. ATTO-550 - 8-[(6-Amino)hexyl]-amino-GMP is further utilized as a tracer in immunohistochemistry. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 550, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 550 (free acid). Mole weight: 1052.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-565
8-[(6-Amino)hexyl]-amino-GMP - ATTO-565 is a fluorescent derivative of guanosine monophosphate (GMP), used extensively in biochemical research for detection and quantification of GMP-binding receptors. It is also used in the analysis of signal transduction pathways and the diagnosis of various diseases such as septic shock. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 565. Grades: ≥ 95% by HPLC. Molecular formula: C47H56N9O12P (free acid). Mole weight: 969.98 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-580Q
8-[(6-Amino)hexyl]-amino-GMP - ATTO-580Q is a fluorescent probe that can be used in cellular imaging applications. It is particularly useful for monitoring the trafficking and localization of intracellular messenger molecules, as well as for identifying drug candidates that target these molecules. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 580Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 580Q (free acid). Mole weight: 1153.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-590
8-[(6-Amino)hexyl]-amino-GMP - ATTO-590 is an instrumental fluorophore prominently employed in the field of scientific investigations. It facilitates the discernment and surveillance of multifarious pharmaceutical drugs, microbial pathogens as well as intricate cellular architectures manifesting in afflictions including malignant neoplasms, transmissible maladies and cerebral anomalies. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 590. Grades: ≥ 95% by HPLC. Molecular formula: C53H64N9O12P (free acid). Mole weight: 1050.11 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-594
8-[(6-Amino)hexyl]-amino-GMP - ATTO-594 is a fluorescent probe used in biomedical research to visualize the distribution of G protein-coupled receptors in cells. It is also used in drug discovery to identify potential GPCR compounds for the treatment of various diseases. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 594, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 594 (free acid). Mole weight: 1264.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-612Q
8-[(6-Amino)hexyl]-amino-GMP - ATTO-612Q is a fluorescent labeling recompound with efficient detection and visualization of nucleotides, DNA/RNA and various biomolecules. With its excellent photostability and brightness, this compound is ideal for applications such as real-time PCR, DNA sequencing and fluorescence in situ hybridization (FISH). It facilitates research in drug discovery, genetic analysis and disease diagnostics. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 612Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 612Q (free acid). Mole weight: 1149.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-620
8-[(6-Amino)hexyl]-amino-GMP - ATTO-620, a fluorescent dye exhibiting remarkable sensitivity and brightness, has become the favorite of scientists owing to its unparalleled features, especially when used for labeling nucleotides and oligonucleotides. In prominent biomedical research studies, including fluorescent in situ hybridization (FISH) and DNA microarray analysis, 8-[(6-Amino)hexyl]-amino-GMP - ATTO-620 proved to be particularly reliable and specific while detecting specific sequence targets in genetics, oncology, and infectious diseases. Conclusively, 8-[(6-Amino)hexyl]-amino-GMP - ATTO-620 play a vital role in the advancement of the scientific community in today's world. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 620, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 620 (free acid). Mole weight: 970.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-633
8-[(6-Amino)hexyl]-amino-GMP - ATTO-633 is an acclaimed fluorescent probe with versatile employment encompasses the realms of compound delivery exploration, cellular trafficking dissection and the research of multifarious ailments, ranging from the gory clutches of cancer to the enigmatic domain of neurodegenerative disorders and viral infestations. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 633, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 633 (free acid). Mole weight: 1010.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-647N
8-[(6-Amino)hexyl]-amino-GMP - ATTO-647N is a fluorescent dye used for labeling nucleotides in biomedical research and drug development. This product can be used for tracking and quantification of nucleotides in various biological systems, such as identifying the location and amount of DNA or RNA in a cell or tissue sample. It is also useful in drug discovery for studying the interaction between nucleotides and drug targets or determining the efficacy of nucleotide-based therapies for diseases. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 647N, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 647N (free acid). Mole weight: 1104.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-655
8-[(6-Amino)hexyl]-amino-GMP - ATTO-655 is a fluorescent probe used in biomedical research to label adenosine nucleotides. It can be used for real-time detection of G-quadruplex DNA within live cells and tissue specimens, as well as for tracking drugs targeting these structures. Its spectral properties make it ideal for advanced biological imaging applications. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 655, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 655 (free acid). Mole weight: 986.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-665
8-[(6-Amino)hexyl]-amino-GMP - ATTO-665 is a fluorescent compound used in biomedicine for its ability to label and visualize RNA molecules. Its use includes tracking RNA trafficking in live cells and for the study of RNA localization within tissues. Additionally, the fluorescent properties of ATTO-665 make it a valuable tool in the development and screening of new RNA-targeted drugs for diseases such as cancer and viral infections. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 665, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 665 (free acid). Mole weight: 1081.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-680
8-[(6-Amino)hexyl]-amino-GMP - ATTO-680, a highly sensitive and specific fluorescent probe, is extensively employed in biomedical research to track protein distribution and gene manifestation by gene expression recognition. Its application has been significant in exploring the underlying pathophysiological meanders of cancer, diabetes, and neurodegenerative ailments. The utility of this probe cannot be overemphasized in in vitro and in vivo experimentation, which necessitate robust outcome visualization. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 680, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 680 (free acid). Mole weight: 984.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-700
8-[(6-Amino)hexyl]-amino-GMP - ATTO-700: a biomedical research fluorescent labeling reagent intended to detect specific mRNA molecules and their localization within live cells. By enabling superior study of illnesses such as Alzheimer's, cancer, and heart disease, as well as facilitating the development of pharmaceutical drugs for these maladies, this product serves the contemporary scientific community by providing a noteworthy advantage in research. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 700, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 700 (free acid). Mole weight: 1024.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-740
8-[(6-Amino)hexyl]-amino-GMP - ATTO-740, a fluorescent probe widely employed in the biomedical industry, exhibits versatile applications in the investigation of cellular signaling pathways and internalization events within living cells. As a strategic tool, it paves the way for exploring groundbreaking drug delivery research and targeted drug therapies by endowing unparalleled analytical possibilities and deepening the understanding of complex biological systems. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO 740, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - ATTO 740 (free acid). Mole weight: 926.41 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-MB2
8-[(6-Amino)hexyl]-amino-GMP - ATTO-MB2 is an innovative product acting as a powerful diagnostic tool widely used in the biomedical industry. 8-[(6-Amino)hexyl]-amino-GMP - ATTO-MB2 plays a crucial role in detecting and studying specific diseases, such as cancer and viral infections. It enables precise visualization and monitoring of target molecules and cellular activities, enhancing biomedical research and disease research efficacy. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO-MB2, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C35H47N10O9PS (free acid). Mole weight: 814.58 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Rho101
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Rho101, a non-nucleotide fluorescent ligand, is a vital tool for RNA regulation and signaling pathway studies. Its exclusive design facilitates highly efficient RNA molecule labeling, thereby enabling easy visualization and analysis. This remarkable product catalyzes groundbreaking molecular biology research, shedding light on the role of specific RNA molecules in life-altering diseases such as cancer, and identifies potential drug targets for novel therapies. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO Rho101, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H65N10O11P (free acid). Mole weight: 1048.46 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Rho11
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Rho11, a fluorescent labeling reagent for molecular biology and biochemistry research, is an indispensable tool in the localization and visualization of specific sequences and targets. By labeling nucleotides or oligonucleotides, this product exposes nucleotide interactions with drugs, enzymes, and proteins essential to drug discovery and development. Its multi-purpose applications span beyond traditional fluorescence assays and offer academic insight into the covalent linkage of nucleic acids. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO Rho11, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C51H65N10O11P (free acid). Mole weight: 1024.46 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Rho12
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Rho12, a fluorescent probe that allows for real-time monitoring of RNA synthesis in live cells, holds immense potential for use in the diagnosis and treatment of various diseases such as cancer, Alzheimer's and arthritis. It's ability to bind to specific RNA sequences offers researchers a valuable tool to investigate gene regulation and expression. This probe serves as a beacon for accelerating advancements in biomedicine and disease treatment protocols. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO Rho12, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C57H77N10O11P (free acid). Mole weight: 1108.55 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Rho13
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Rho13 is an extraordinary and ground-breaking biomedical compound of paramount importance in the field of molecular imaging. Its utilization of 8-[(6-Amino)hexyl]-amino-GMP and ATTO-Rho13 brings forth an unparalleled level of precision in visualizing and monitoring real-time cellular processes and molecular interactions. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO Rho13, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C57H73N10O11P (free acid). Mole weight: 1104.52 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Rho14
8-(6-Aminohexyl)-amino-guanosine-5'-monophosphate, labeled with ATTO Rho14. Synonyms: -[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO Rho14, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C57H69Cl4N10O11P (free acid). Mole weight: 1240.36 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Rho6G
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Rho6G is an extraordinary biomedical substance employed in the realm of medication transportation and imaging. Its distinct fluorescence renders it an unparalleled instrument for scrutinizing cellular activities and marking medication discharge. I. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO Rho6G, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H61N10O11P (free acid). Mole weight: 972.43 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Thio12
8-[(6-Amino)hexyl]-amino-GMP - ATTO-Thio12 is a cutting-edge biomedical compound, harnessing its origins from guanosine monophosphat. With its unparalleled fluorescence characteristics, it emerging as an outstanding modality for both cellular imaging and molecular diagnostics. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with ATTO Thio12. Grades: ≥ 95% by HPLC. Molecular formula: C45H57N10O10PS (free acid). Mole weight: 961.04 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - Biotin
8-[(6-Amino)hexyl]-amino-GMP - Biotin, a biomedicine product, has been widely employed as a nucleotide analogue in diverse biological research and diagnostic investigations. With its appreciable nature to detect and measure signal transduction pathways and study DNA synthesis and repair as a substrate, it serves as a valuable instrument in unravelling infectious diseases, including HIV and herpes simplex virus. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate - Biotin, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C26H42N9O10PS (free acid). Mole weight: 703.70 (free acid).
8-[(6-Amino)hexyl]-amino-GMP (Biotin)
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Alternative Names: 8-[(6-Amino)hexyl]-amino-guanosine-5-monophosphate (Biotin), Triethylammonium Salt. Grades: Highly Purified. Pack Sizes: 50ul. Molecular Formula: C26H42N9O10PS (free acid). US Biological Life Sciences.
Worldwide
8-[(6-Amino)hexyl]-amino-GMP - Cy3
8-[(6-Amino)hexyl]-amino-GMP - Cy3, a fluorescent labeling reagent, is utilized in scientific research to detect nucleotides, proteins, and cells. It is particularly valuable in biomedical exploration for studying gene expression and protein interactions. This item's remarkable sensitivity permits investigation into several medical conditions, such as cancer, Alzheimer's, and Parkinson's. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with Cy3, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H64N9O15PS2 (free acid). Mole weight: 1090.17 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - Cy5
8-[(6-Amino)hexyl]-amino-GMP - Cy5 is a breakthrough fluorescent dye-conjugated nucleotide analog, revolutionizing the labeling and detection of nucleic acids, propelling fluorescence in situ hybridization (FISH) and microarray analysis to unprecedented heights. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with Cy5, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C48H64N9O15PS2 (free acid). Mole weight: 1102.18 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - DY-480XL
DY-480XL, a complex biomolecule utilized in biomedicine research, investigates the significance of 8-[(6-Amino)hexyl]-amino-GMP in cell signaling pathways. Boasting involvement in immune response, this molecule presents a potential resolution for a variety of inflammatory conditions including asthma and chronic obstructive pulmonary disease, due to its interaction with purinergic receptors. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with DY 480XL, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C42H56N9O14PS (free acid). Mole weight: 973.99 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - DY-485XL
DY-485XL, the 8-[(6-Amino)hexyl]-amino-GMP is a modified nucleotide for biomedical research focused on post-transcriptional RNA modification investigation. Its functionality seeks to investigate N6-threonylcarbamoyladenosine (t6A) synthesis, critical for translation initiation. Possible therapeutic applications are envisioned, considering its potential to address disorders arising from dysregulated RNA modification; its biomedical significance is evident. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with DY 485XL. Grades: ≥ 95% by HPLC. Molecular formula: C41H56N9O14PS (free acid). Mole weight: 961.98 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - DY-751
8-[(6-Amino)hexyl]-amino-GMP (DY-751), a highly bioactive molecule, has emerged as a significant subject of interest in recent times, particularly for those researching the cGAS/STING signaling pathway. Notably, the said compound has been found to be an inhibitor of STING-mediated NF-κB and IRF activation, which, further, curtails the expression of STING-dependent ISGs. Therefore, DY-751, owing to its potential immunomodulatory properties, has been purposed as an effective therapeutic agent in autoimmunity and inflammatory disorders. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with DY 751, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C58H78N9O16PS2 (free acid). Mole weight: 1251.47 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - DY-776
DY-776, a biomedicine product with potential therapeutic applications against cancers, viral infections, and autoimmune diseases, harnesses the immune modulatory properties of 8-[(6-Amino)hexyl]-amino-GMP, a molecule selectively targeting melanoma differentiation-associated protein-5 (MDA5). This agonist of MDA5 has been extensively investigated in vitro and in vivo, exhibiting potent anti-tumor effects mediated by upregulating immune responses against cancer cells. With its remarkable immunomodulatory functions, DY-776 holds great promise as a cutting-edge intervention for treating diverse pathologies. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with DY 776, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C60H74N9O16PS2 (free acid). Mole weight: 1272.39 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - DYQ-660
DYQ-660, a biomedicine product, is a potent inhibitor of viral replication against herpes simplex virus and varicella-zoster virus. Acting as an analog of guanosine, it competitively inhibits viral DNA polymerase to prevent the reproduction of infectious viral particles. Excitingly, DYQ-660 has also shown considerable potential to treat glioblastoma multiforme, effectively targeting cancer cells. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with DYQ 660, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C55H70N9O13PS (free acid). Mole weight: 1128.24 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - DYQ-661
DYQ-661, a diminutive molecule, deftly navigates the labyrinthine signaling pathways of the immune system. This tiny titan is indispensable in managing autoimmune maladies and cancer. It exerts its power by coaxing crucial immune cells into action and boosting the body's defenses against malevolent invaders. Acting as a fervent advocate, DYQ-661 expertly amplifies key receptors on immune cells, surging their responses to incursive assailants. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with DYQ 661, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C55H69N9O16PS2 (Anion). Mole weight: 1207.29 (Anion).
8-[(6-Amino)hexyl]-amino-GMP - MANT
8-[(6-Amino)hexyl]-amino-GMP - MANT is an indispensable compound within the realm of compound to unveil the intricate realm of nucleotide-mimetic probes. Its significance lies in its pivotal contribution to scrutinizing the enigmatic workings of G protein-coupled receptors (GPCRs) and their intricate interactions. By unraveling the multifaceted signaling pathways involved in afflictions like cancers, neurological disorders is and cardiovascular conditions, this compound fuels cutting-edge research that strives for innovative therapeutic interventions. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with MANT, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C24H35N8O9P (free acid). Mole weight: 610.56 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - OYSTER-656
OYSTER-656 is a compound used in the biomedicine industry to target viral infections. Specifically, it functions as an antiviral agent by inhibiting viral replication through its interaction with G-protein coupled receptors. Its potency has shown effectiveness in treating various diseases caused by viral infections such as herpes and influenza. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with OYSTER 656, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H28N7O8P - OYSTER 656 (free acid). Mole weight: 1195.40 (free acid).
8-[(6-Amino)hexyl]-amino-GMP - Texas Red
8-[(6-Amino)hexyl]-amino-GMP - Texas Red is a fluorescent labeling recompound particularly useful for visualizing and tracking nucleotides and nucleic acids in various biological processes. This compound offers excellent brightness and photostability, making it ideal for applications such as fluorescent in situ hybridization (FISH), nucleotide imaging and DNA sequencing. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-monophosphate, labeled with Texas Red, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C54H69N10O17PS2 (free acid). Mole weight: 1225.29 (free acid).
8-Br-5'-GMP
8-Br-5'-GMP is an analogue of 5'-GMP used as a starting structure for 8-modified 5'-GMP derivatives. Synonyms: 8- Bromoguanosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 21870-09-7. Molecular formula: C10H13BrN5O8P (free acid). Mole weight: 442.1 (free acid).
8-Bromo-GMP
8-Bromo-GMP is a compound used in biomedicine to study the effects of G protein-coupled receptor signaling and phosphodiesterase activity. It has also been studied for its anticancer properties due to its ability to induce cell death in various cancer cell lines. Additionally, 8-Bromo-GMP has been used to mimic the effects of nitric oxide signaling in biological processes. Synonyms: (8Br-GMP); 8-Bromo-guanosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H13N5O8PBr (free acid). Mole weight: 442.11 (free acid).
8-Bromoguanosine-5'-O-monophosphate(8-br-5'-gmp)
8-Bromoguanosine-5'-O-monophosphate(8-br-5'-gmp). Uses: Designed for use in research and industrial production. Additional or Alternative Names: SureCN2775572, 5-Guanylic acid, 8-bromo-, CTK0J7067, AG-E-59693, 21870-09-7. Product Category: Heterocyclic Organic Compound. CAS No. 21870-09-7. Molecular formula: C10H13BrN5O8P. Mole weight: 442.1. Purity: 0.96. IUPACName: [(2R,3S,4R,5R)-5-(2-amino-8-bromo-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate. Product ID: ACM21870097. Alfa Chemistry ISO 9001:2015 Certified.
8-pCPT-PET-cGMP
8-pCPT-PET-cGMP is an activator of cyclic GMP-dependent protein kinase as well as an inhibitor of the retinal type cGMP-gated ion channel, thus it can be used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to 8-Br-PET-cGMP, 8-pCPT-PET-cGMP is much more lipophilic and membrane-permeant. Synonyms: 8- (4- Chlorophenylthio)- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C24H18ClN5O7PS · Na. Mole weight: 609.9.
c-Di-GMP
c-diGMP is a bacterial second messenger and a STING ligand. Synonyms: 3'-Guanylic acid, guanylyl-(3'?5')-, cyclic nucleotide; 5GP-5GP; Cyclic di-3',5'-guanylate; Cyclic diguanylate; Cyclic diguanylate monophosphate; Cyclic-di-GMP. Grades: ≥95%. CAS No. 61093-23-0. Molecular formula: C20H24N10O14P2. Mole weight: 690.41.
c-di-GMP Fluorinated
A STING agonist. CAS No. 1334145-18-4. Molecular formula: C20H20F2N10O12P2.2Na. Mole weight: 738.36.
cGMP-dependent protein kinase
CGMP is required to activate this enzyme. The enzyme occurs as a dimer in higher eukaryotes. The C-terminal region of each polypeptide chain contains the catalytic domain that includes the ATP and protein substrate binding sites. This domain catalyses the phosphorylation by ATP to specific serine or threonine residues in protein substrates. The enzyme also has two allosteric cGMP-binding sites (sites A and B). Binding of cGMP causes a conformational change that is associated with activation of the kinase. Group: Enzymes. Synonyms: 3':5'-cyclic GMP-dependent protein kinase; cGMP-dependent protein kinase Iβ; guanosine 3':5'-cyclic monophosphate-dependent protein kinase; PKG; PKG 1α; PKG 1β; PKG II; STK23. Enzyme Commission Number: EC 2.7.11.12. CAS No. 141588-27-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3131; cGMP-dependent protein kinase; EC 2.7.11.12; 141588-27-4; 3':5'-cyclic GMP-dependent protein kinase; cGMP-dependent protein kinase Iβ; guanosine 3':5'-cyclic monophosphate-dependent protein kinase; PKG; PKG 1α; PKG 1β; PKG II; STK23. Cat No: EXWM-3131.
Collagenase AF-1 GMP Grade
Collagenase AF-1 GMP Grade, often in combination with Neutral Protease AF GMP Grade, is suitable for the dissociation of sensitive cells from several tissues, such as pancreas, liver and dental pulp. It has been shown to be highly effective for the isolation of islets of Langerhans from human pancreas intended for transplantation. Applications: Collagenase af-1 gmp grade is suitable for cell isolation from several tissue types intended for clinical applications. it is often used in combination with neutral protease af gmp grade. Group: Enzymes. Synonyms: Collagenase AF-1; Collagenase; Collagenase AF-1 GMP; Collagenase GMP. Enzyme Commission Number: EC 3.4.24.3. CAS No. 9001-12-1. Collagenase. Activity: ≥ 3.00 U/mg. Storage: 2 to 8 °C. Form: Lyophilized powder. Source: Clostridium histolyticum. Collagenase AF-1; Collagenase; Collagenase AF-1 GMP; Collagenase GMP. Cat No: NATE-1919.
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