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| Product | Description | |
|---|---|---|
| GNE-477 | GNE-477 is a dual inhibitor of PI3K (IC50 = 4 nM for PI3Kα) and mTOR (apparent Ki=21 nM). Uses: Designed for use in research and industrial production. Additional or Alternative Names: GNE-477; GNE477; GNE 477. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1032754-81-6. Molecular formula: C21H28N8O3S2. Mole weight: 504.63. Purity: >98%. IUPACName: 5-(7-methyl-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine. Canonical SMILES: NC1=NC=C(C2=NC(N3CCOCC3)=C4C(C(C)=C(CN5CCN(S(=O)(C)=O)CC5)S4)=N2)C=N1. Product ID: ACM1032754816. Alfa Chemistry ISO 9001:2015 Certified. Categories: GE 477L Nuclear Detection and Reporting System. |  |
| GNE-477 | GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα and Kiapp of 21 nM for mTOR. Synonyms: GNE-477, GNE477, GNE 477. Grades: >98%. CAS No. 1032754-81-6. Molecular formula: C21H28N8O3S2. Mole weight: 504.63. |  |
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