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| Product | Description | |
|---|---|---|
| GNF 5837 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| GNF 5837 | GNF 5837. Group: Biochemicals. Grades: Purified. CAS No. 1033769-28-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| GNF 5837 | GNF 5837 is a potent and selective pan-Trk inhibitor that blocks tumor gowth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF. GNF 5837 displays antiproliferative effects in cellular Ba/F3 assays with IC50 values of 7, 9 and 11 nM for cells expressing Tel-TrkC, Tel-TrkB and Tel-TrkA respectively. Synonyms: GNF5837; GNF-5837; GNF 5837. 1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-methyl-3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]urea. CAS No. 1033769-28-6. Molecular formula: C28H21F4N5O2. Mole weight: 535.503. |  |
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