Gossypol Suppliers USA
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Product | Description | |
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Gossypol Quick inquiry Where to buy Suppliers range | Gossypol is an orally-active polyphenolic aldehyde with potential antineoplastic activity. Derived primarily from unrefined cottonseed oil, gossypol induces cell cycle arrest at the G0/G1 phase, thereby inhibiting DNA replication and inducing apoptosis. This agent also inhibits cell-signaling enzymes, resulting in inhibition of cell growth, and may act as a male contraceptive. Uses: Antimicrobial. Synonyms: 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde. Grades: > 98 %. CAS No. 303-45-7. Molecular formula: C30H30O8. Mole weight: 518.55. | |
Gossypol Quick inquiry Where to buy Suppliers range | 100mg Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Stains & Indicators. Formula: C30H30O8. CAS No. 303-45-7. Prepack ID 41989683-100mg. Molecular Weight 518.6. See USA prepack pricing. | |
Gossypol Quick inquiry Where to buy Suppliers range | Gossypol. Group: Biochemicals. Alternative Names: 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; (±)-Gossypol; 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-diisopropyl-2,2'-binaphthyl-8,8'-dialdehyde; 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-diisopropyl[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-2,2'-binaphthalene-8,8'-dicarboxaldehyde; 1,6,7,1',6',7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2']binaphthalenyl-8,8'-dicarboxaldehyde; 2,2'-Bis[1,6,7-trihydroxy-3-methyl-5-isopropyl-8-aldehydonaphthyl]; 2,2'-Bis[8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthyl]; BL 193; Gossypol; NSC 56817; NSC 624336; No Fertil; Pogosin; Tash 1. Grades: Highly Purified. CAS No. 303-45-7. Pack Sizes: 100ug. Molecular Formula: C30H30O8, Molecular Weight: 518.549999999999. US Biological Life Sciences. | Worldwide |
Gossypol Quick inquiry Where to buy Suppliers range | Gossypol. CAS No. 303-45-7. | |
Gossypol Quick inquiry Where to buy Suppliers range | Gossypol. Uses: For analytical and research use. Group: Herbal Medicinal Products Standards; Pharma & Vet Compounds & Metabolites; Pharma & Vet Compounds & Metabolites. CAS No. 303-45-7. Pack Sizes: 10MG. IUPAC Name: 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde. Molecular formula: C30H30O8. Mole weight: 518.55. Catalog: APS303457. Assay: ≥95.0% (HPLC). SMILES: CC (C)c1c (O)c (O)c (C=O)c2c (O)c (c (C)cc12)c3c (C)cc4c (C (C)C)c (O)c (O)c (C=O)c4c3O. Format: Neat. Shipping: Room Temperature. | |
Gossypol Quick inquiry Where to buy Suppliers range | Gossypol. Group: Biobased Products. Alternative Names: 2,2-Bis(1,6,7-trihydroxy-3-methyl-5-isopropyl-8-aldehydonaphthalene). Grades: 98%. CAS No. 303-45-7. Product ID: BBC303457. Molecular formula: C30H30O8. Mole weight: 518.55. IUPAC Name: 7-(8-Formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde. Appearance: Powder. Density: 1.19 g/ml. SMILES: CC1=CC2=C (C (=C (C (=C2C (C)C)O)O)C=O)C (=C1C3=C (C4=C (C=C3C)C (=C (C (=C4C=O)O)O)C (C)C)O)O. | |
Gossypol acetate Quick inquiry Where to buy Suppliers range | Gossypol acetate - Product ID: NST-10-197. Category: Polyphenols. Purity: 98%. Test method: HPLC. CAS No. 12542-36-8. Pack Sizes: 1g, 2g, 5g, 10g. Appearance: White to yellow Powder. Molecular formula: C32H34O10. Mole weight: 578.61. Storage: +2 +8 °C. | |
Gossypol-acetic acid Quick inquiry Where to buy Suppliers range | Gossypol-acetic acid. Group: Main Products. Alternative Names: aceticacidgossypol;GOSSYPOL ACETATE;GOSSYPOL-ACETIC ACID;1,1,6,6,7,7-hexahydroxy-3,3-dimethyl-5,5-bis(1-methylethyl)[2,2-binaphthalene]-8,8-dicarboxaldehyde-acetic acid; Gossypolaceticacidcomplex; GOSSYPOL ACETATE 98%;GOSSYPOLMONOACETICACID;1, 1, 6, 6, 7, 7-Hexahydroxy-3, 3-dimethyl-5, 5-bis(1-methylethyl)[2, 2-binaphthalene]-8, 8-dicarboxaldehyde-acetic acid. Grades: 99%. CAS No. 12542-36-8. Product ID: ACM12542368. Molecular formula: C32H34O10. Mole weight: 578.61. IUPAC Name: aceticacid;7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde. Appearance: Yellow crystal powder. Boiling Point: 707.9ºC at 760 mmHg. Melting Point: 164-168°C. Flash Point: 395.9ºC. | |
Gossypol-acetic acid Quick inquiry Where to buy Suppliers range | Gossypol-acetic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 12542-36-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C30H30O8·C2H4O2. US Biological Life Sciences. | Worldwide |
Gossypol Acetic Acid Quick inquiry Where to buy Suppliers range | Gossypol Acetic Acid is a phenol compound from plants of the Gossypium genus, Malvaceae. It binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. It exhibits antiviral activity at low concentration. Uses: Spermatocidal agents. Synonyms: Gossypol acetate; Acetate gossypol. Grades: 98 % by HPLC. CAS No. 12542-36-8. Molecular formula: C32H34O10. Mole weight: 578.61. | |
Gossypol D2 (binaphthalene-4,4'-D2) Quick inquiry Where to buy Suppliers range | Gossypol D2 (binaphthalene-4,4'-D2). Uses: For analytical and research use. Group: Pharma & Vet Compounds & Metabolites; Pharma & Vet Compounds & Metabolites. CAS No. 113580-77-1. IUPAC Name: 5-deuterio-7-(4-deuterio-8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methyl-2-naphthyl)-2,3,8-trihydroxy-4-isopropyl-6-methyl-naphthalene-1-carbaldehyde. Molecular formula: C302H2H28O8. Mole weight: 520.57. Catalog: APS113580771. SMILES: [2H]c1c (C)c (c (O)c2c (C=O)c (O)c (O)c (C (C)C)c12)c3c (C)c ([2H])c4c (C (C)C)c (O)c (O)c (C=O)c4c3O. Format: Neat. Product Type: Stable Isotope Labelled. | |
Acetate gossypol Quick inquiry Where to buy Suppliers range | Acetate gossypol. Group: Biochemicals. Alternative Names: Gossypol acetic acid. Grades: Plant Grade. CAS No. 12542-36-8. Pack Sizes: 20mg. Molecular Formula: C32H34O10, Molecular Weight: 578.606. US Biological Life Sciences. | Worldwide |
Acetate Gossypol Quick inquiry Where to buy Suppliers range | Acetate Gossypol. Group: Biobased Products. Alternative Names: Gossypol-acetic acid. Grades: 98%. CAS No. 12542-36-8. Product ID: BBC12542368. Molecular formula: C32H34O10. Mole weight: 578.61. IUPAC Name: Acetic acid;7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde. Appearance: Powder. SMILES: CC1=CC2=C (C (=C (C (=C2C (C)C)O)O)C=O)C (=C1C3=C (C4=C (C=C3C)C (=C (C (=C4C=O)O)O)C (C)C)O)O. CC (=O)O. | |
(S)-Gossypol acetic acid Quick inquiry Where to buy Suppliers range | (S)-Gossypol acetic acid, a Bcl-2 inhibitor, could effectively induce the death of Jurkat cells in which Bcl-2 or Bcl-xL is overexpressed. IC50: 18.1μM and 22.9μM for Bcl-2 and Bcl-xL respectively. Uses: (s)-gossypol acetic acid is a bcl-2 inhibitor that could effectively induce the death of jurkat cells in which bcl-2 or bcl-xl is overexpressed. Synonyms: (S)-(+)-Gossypol acetic acid. Grades: 98%. CAS No. 1189561-66-7. Molecular formula: C32H34O10. Mole weight: 578.61. | |
AT101 Quick inquiry Where to buy Suppliers range | AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM. Synonyms: AT-101; AT 101; AT101. Grades: >98%. CAS No. 90141-22-3. Molecular formula: C30H30O8·C2H4O2. Mole weight: 578.6. | |
AT-101 acetic acid Quick inquiry Where to buy Suppliers range | AT101 acetic acid is orally bioavailable solvate of R-(-)-enantiomer of gossypol with potential antineoplastic activity. It is used as the treatment of non Hodgkin's lymphoma, prostate cancer, and non small cell cancer. It binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM. It induces apoptosis in vitro through activation of caspase-9. It delays onset of androgen-independent growth of VCaP prostate cancer xenografts in vivo. It was developed by Ascenta and in clinical phase 2. Uses: At101 acetic acid is used as the treatment of non hodgkin's lymphoma, prostate cancer, and non small cell cancer. Synonyms: AT-101 acetic acid; AT 101 acetic acid; AT101 acetic acid; (R)-(-)-Gossypol acetic acid;(-)-Gossypol acetic acid;(R)-Gossypol acetic acid;Acetic acid 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde. Grades: >98 %. CAS No. 866541-93-7. Molecular formula: C32H34O10. Mole weight: 578.61. | |
Gossypolidine-4-aminoantipyridine Quick inquiry Where to buy Suppliers range | Gossypolidine-4-aminoantipyridine. | |
Lactate Dehydrogenase A Inhibitor, FX11 (LDHA Inhibitor I, LDH-A Inhibitor I, LDH-M Inhibitor I, LDHM Inhibitor I) Quick inquiry Where to buy Suppliers range | A cell permeable, gossypol analog that acts as a selective, reversible, and NADH competitive inhibitor of lactate dehhydrogenase A (LDHA; Ki = 8uM for human liver LDHA). Does not affect the activities of LDHB and glyceraldehyde-3-phosphate dehydrogenase even at higher concentrations. Shown to increase oxygen consumption, reactive oxygen species production, and cell death in P493 human lymphoma B cells. Also shown to reduce mitochondrial transmembrane potential and ATP levels and increase AMP kinase activity. Exhibits synergistic toxicity in P493 cells when combined with FK866. Blocks the progression of human lymphoma and pancreatic cancer xenografts and when used in combination with FK866 it induces lymphoma regression. Group: Biochemicals. Grades: Highly Purified. CAS No. 213971-34-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |