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| Product | Description | |
|---|---|---|
| Gossypol | 100mg Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Stains & Indicators. Formula: C30H30O8. CAS No. 303-45-7. Prepack ID 41989683-100mg. Molecular Weight 518.6. See USA prepack pricing. |  |
| Gossypol | Gossypol binds to Bcl-xL protein and Bcl-2 protein with K i s of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: BL 193. CAS No. 303-45-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13407. |  |
| Gossypol | Gossypol. Group: Biochemicals. Alternative Names: 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; (±)-Gossypol; 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-diisopropyl-2,2'-binaphthyl-8,8'-dialdehyde; 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-diisopropyl[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-2,2'-binaphthalene-8,8'-dicarboxaldehyde; 1,6,7,1',6',7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2']binaphthalenyl-8,8'-dicarboxaldehyde; 2,2'-Bis[1,6,7-trihydroxy-3-methyl-5-isopropyl-8-aldehydonaphthyl]; 2,2'-Bis[8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthyl]; BL 193; Gossypol; NSC 56817; NSC 624336; No Fertil; Pogosin; Tash 1. Grades: Highly Purified. CAS No. 303-45-7. Pack Sizes: 100ug. Molecular Formula: C30H30O8, Molecular Weight: 518.549999999999. US Biological Life Sciences. |  Worldwide |
| Gossypol | Gossypol is an orally-active polyphenolic aldehyde with potential antineoplastic activity. Derived primarily from unrefined cottonseed oil, gossypol induces cell cycle arrest at the G0/G1 phase, thereby inhibiting DNA replication and inducing apoptosis. This agent also inhibits cell-signaling enzymes, resulting in inhibition of cell growth, and may act as a male contraceptive. Uses: Antimicrobial. Synonyms: 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde. Grades: > 98 %. CAS No. 303-45-7. Molecular formula: C30H30O8. Mole weight: 518.55. |  |
| Gossypol acetate | Gossypol acetate - Product ID: NST-10-197. Category: Polyphenols. Purity: 98%. Test method: HPLC. CAS No. 12542-36-8. Pack Sizes: 1g, 2g, 5g, 10g. Appearance: White to yellow Powder. Molecular formula: C32H34O10. Mole weight: 578.61. Storage: +2 +8 °C. |  |
| Gossypol (acetic acid) | Gossypol acetic acid ((±)-Gossypol-acetic acid) binds to Bcl-xL protein and Bcl-2 protein with K i s of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Gossypol-acetic acid; BL-193 (acetic acid). CAS No. 12542-36-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17510. | |
| Gossypol acetic acid | Gossypol acetic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GOSSYPOL, ACETATE (SALT);2,3,8-trihydroxy-6-methyl-4-propan-2-yl-7-(1,6,7-trihydroxy-8-methanoyl-3-methyl-5-propan-2-yl-naphthalen-2-yl)naphthalene-1-carbaldehyde;7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-meth. Product Category: Heterocyclic Organic Compound. CAS No. 5453-4-3. Molecular formula: C32H34O10. Product ID: ACM5453043. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Gossypol-acetic acid | Gossypol-acetic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 12542-36-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C30H30O8·C2H4O2. US Biological Life Sciences. | Worldwide |
| Gossypol-acetic acid | Gossypol-acetic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: aceticacidgossypol;GOSSYPOL ACETATE;GOSSYPOL-ACETIC ACID;1,1,6,6,7,7-hexahydroxy-3,3-dimethyl-5,5-bis(1-methylethyl)[2,2-binaphthalene]-8,8-dicarboxaldehyde-acetic acid;Gossypolaceticacidcomplex;GOSSYPOL ACETATE 98%;GOSSYPOLMONOACETICACID;1,1,6,6,7,7-Hexahydroxy-3,3-dimethyl-5,5-bis(1-methylethyl)[2,2-binaphthalene]-8,8-dicarboxaldehyde-acetic acid. Appearance: Yellow crystal powder. CAS No. 12542-36-8. Molecular formula: C32H34O10. Mole weight: 578.61. Purity: 0.99. IUPACName: aceticacid;7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde. Canonical SMILES: CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C.CC(=O)O. Product ID: ACM12542368. Alfa Chemistry ISO 9001:2015 Certified. Categories: Gossypol acetic acid. | |
| Gossypol Acetic Acid | Gossypol Acetic Acid is a phenol compound from plants of the Gossypium genus, Malvaceae. It binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. It exhibits antiviral activity at low concentration. Uses: Spermatocidal agents. Synonyms: Gossypol acetate; Acetate gossypol. Grades: 98 % by HPLC. CAS No. 12542-36-8. Molecular formula: C32H34O10. Mole weight: 578.61. | |
| Gossypolone | Gossypolone is an RNA-binding protein Musashi-1 inhibitor with a K i of 12 nM. Gossypolone disrupts the Musashi-numb RNA interaction and directly binds to the RBD1 of MSI1 protein. Gossypolone can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4547-72-2. Pack Sizes: 1 mg. Product ID: HY-119734. | |
| Acetate gossypol | Acetate gossypol. Group: Biochemicals. Alternative Names: Gossypol acetic acid. Grades: Plant Grade. CAS No. 12542-36-8. Pack Sizes: 20mg. Molecular Formula: C32H34O10, Molecular Weight: 578.606. US Biological Life Sciences. | Worldwide |
| (R)-(-)-Gossypol | (R)-(-)-Gossypol (AT-101) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM, respectively. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 90141-22-3. Molecular formula: C30H30O8. Mole weight: 518.55. Product ID: ACM90141223. Alfa Chemistry ISO 9001:2015 Certified. | |
| (S)-Gossypol (acetic acid) | (S)-Gossypol is the isomer of a natural product Gossypol. (S)-Gossypol binds to the BH3-binding groove of Bcl-xL and Bcl-2 proteins with high affinity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-(+)-Gossypol acetic acid. CAS No. 1189561-66-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15464D. | |
| (S)-Gossypol acetic acid | (S)-Gossypol acetic acid, a Bcl-2 inhibitor, could effectively induce the death of Jurkat cells in which Bcl-2 or Bcl-xL is overexpressed. IC50: 18.1μM and 22.9μM for Bcl-2 and Bcl-xL respectively. Uses: (s)-gossypol acetic acid is a bcl-2 inhibitor that could effectively induce the death of jurkat cells in which bcl-2 or bcl-xl is overexpressed. Synonyms: (S)-(+)-Gossypol acetic acid. Grades: 98%. CAS No. 1189561-66-7. Molecular formula: C32H34O10. Mole weight: 578.61. | |
| AT101 | AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM. Synonyms: AT-101; AT 101; AT101. Grades: >98%. CAS No. 90141-22-3. Molecular formula: C30H30O8·C2H4O2. Mole weight: 578.6. | |
| AT-101 acetic acid | AT101 acetic acid is orally bioavailable solvate of R-(-)-enantiomer of gossypol with potential antineoplastic activity. It is used as the treatment of non Hodgkin's lymphoma, prostate cancer, and non small cell cancer. It binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM. It induces apoptosis in vitro through activation of caspase-9. It delays onset of androgen-independent growth of VCaP prostate cancer xenografts in vivo. It was developed by Ascenta and in clinical phase 2. Uses: At101 acetic acid is used as the treatment of non hodgkin's lymphoma, prostate cancer, and non small cell cancer. Synonyms: AT-101 acetic acid; AT 101 acetic acid; AT101 acetic acid; (R)-(-)-Gossypol acetic acid;(-)-Gossypol acetic acid;(R)-Gossypol acetic acid;Acetic acid 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde. Grades: >98 %. CAS No. 866541-93-7. Molecular formula: C32H34O10. Mole weight: 578.61. | |
| Lactate Dehydrogenase A Inhibitor, FX11 (LDHA Inhibitor I, LDH-A Inhibitor I, LDH-M Inhibitor I, LDHM Inhibitor I) | A cell permeable, gossypol analog that acts as a selective, reversible, and NADH competitive inhibitor of lactate dehhydrogenase A (LDHA; Ki = 8uM for human liver LDHA). Does not affect the activities of LDHB and glyceraldehyde-3-phosphate dehydrogenase even at higher concentrations. Shown to increase oxygen consumption, reactive oxygen species production, and cell death in P493 human lymphoma B cells. Also shown to reduce mitochondrial transmembrane potential and ATP levels and increase AMP kinase activity. Exhibits synergistic toxicity in P493 cells when combined with FK866. Blocks the progression of human lymphoma and pancreatic cancer xenografts and when used in combination with FK866 it induces lymphoma regression. Group: Biochemicals. Grades: Highly Purified. CAS No. 213971-34-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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