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| Product | Description | |
|---|---|---|
| GRI 977143 | GRI 977143. Group: Biochemicals. Grades: Purified. CAS No. 325850-81-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| GRI 977143 | GRI 977143 is a selective and non-lipid agonist of lysophosphatidic acid 2 (LPA2) receptor (EC50 = 3.3 μM) exhibiting no activity for other LPA GPCRs at concentrations up to 10 μM. GRI 977143 inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. It also activates ERK1/2 survival pathway. Synonyms: GRI977143; GRI-977143; GRI 977143; 2-[[3-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]benzoic acid. Grades: ≥98% by HPLC. CAS No. 325850-81-5. Molecular formula: C22H17NO4S. Mole weight: 391.44. |  |
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