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| Product | Description | |
|---|---|---|
| GSK0660 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| GSK0660 | GSK0660 is a selective PPARδ antagonist. GSK0660 blocks the effect of TNFα on the expressions of cytokines involved in leukocyte recruitment, including CCL8, CCL17, and CXCL10, and it may block TNFα-induced retinal leukostasis. Synonyms: GSK0660; GSK-0660; GSK 0660. Grades: 96%. CAS No. 1014691-61-2. Molecular formula: C19H18N2O5S2. Mole weight: 418.48. |  |
| PT-S58 | PT-S58 is a full peroxisome proliferator-activated receptor (PPAR) β/δ antagonist as a derivative of GSK0660. But PT-S58 has a three-fold higher affinity for the receptor than GSK0660. PT-S58 can inhibit agonist-induced target gene expression. Unlike GSK0660, PT-S58 can block the recruitment co-repressor molecules such as SMRT. Synonyms: PT-S58; PT-S-58; PT-S 58. methyl 3-(N-(4-(tert-butylamino)-2-methoxyphenyl)sulfamoyl)thiophene-2-carboxylate. Grades: 98%. CAS No. 1356497-92-1. Molecular formula: C17H22N2O5S2. Mole weight: 398.49. | |
| ST247 | ST247 is a selective and inverse peroxisome proliferator-activated receptor (PPAR)β/δ agonist with IC 50 value of 19 nm, 10-fold more potent than GSK0660 with IC50 value of 210 nM. Synonyms: ST247; ST-247; ST 247. methyl 3-(N-(4-(hexylamino)-2-methoxyphenyl)sulfamoyl)thiophene-2-carboxylate. Grades: 98%. CAS No. 1356497-91-0. Molecular formula: C19H26N2O5S2. Mole weight: 426.55. | |
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