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| Product | Description | |
|---|---|---|
| GT 2016 | GT 2016. Group: Biochemicals. Grades: Purified. CAS No. 152241-24-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| GT 2016 | GT 2016 is a high affinity and brain-penetrant histamine H3 receptor antagonist (Ki = 43.8 nM). It displays selectivity against H1 and H2 receptors (IC50 >10 μM). GT 2016 increases the release of histamine in the cerebral cortex. GT 2016 exhibits no effect on histamine methyltransferase in vitro at concentrations up to 3 μM. Synonyms: GT-2016,GT2016, GT 2016; 5-Cyclohexyl-1-[4-(1H-imidazol-5-yl)-1-piperidinyl]-1-pentanone. Grades: ≥98% by HPLC. CAS No. 152241-24-2. Molecular formula: C19H31N3O. Mole weight: 317.47. |  |
| BIA10-2474 | This active molecular is a reversible FAAH (fatty acid amide hydrolase) inhibitor that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (except the brain and spinal cord) under the development of Bial-Portela & Ca. SA. BIA 10-2474 can interact with the human endocannabinoid system and was inpplicated in the treatment of a range of different medical conditions including anxiety, Parkinson's disease, chronic pain of multiple sclerosis, cancer, hypertension and obesity. Clinical trial with BIA 10-2474 was on-going. However, severe adverse events occurred in January 2016 affecting 5 patients, including leading to the death of one. Uses: Neurological disorders; pain; psychiatric disorders. Synonyms: BIA 10-2474; BIA-10-2474; BIA10-2474; N-cyclohexyl-N-methyl-4-(1-oxidopyridin-1-ium-3-yl)imidazole-1-carboxamide;UNII-5AP1ZW859M; SCHEMBL427970; 5AP1ZW859M; GTPL9001; DOWVMJFBDGWVML-UHFFFAOYSA-N. Grades: 98%. CAS No. 1233855-46-3. Molecular formula: C16H20N4O2. Mole weight: 300.36. | |
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