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| Product | Description | |
|---|---|---|
| Guaiol | (?)-Guaiol is a sesquiterpene alcohol that has been found in several traditional Chinese medicinal plants and has antiproliferative, pro-autophagic, insect repellent, and insecticidal biological activities.1,2,3 It selectively inhibits proliferation of A549 and H1299 non-small cell lung carcinoma (NSCLC) cells over BEAS-2B normal lung cells (IC50s = 121.7, 211.5, and 297.1 μM, respectively).1 It also dose-dependently induces formation of DNA double-strand breaks (DSBs) and autophagy in A549 and H1299 cells and increases levels of microtubule-associated protein 1 light chain 3 isoform II (LC3-II). (?)-Guaiol (8 mg/kg three times per week) inhibits tumor growth in an NSCLC mouse xenograft model. It deters A. aegypti and A. quadrimaculatus mosquitoes from feeding on a synthetic blood substitute with a biting-deterrent index (BDI) of 0.82 when used at a concentration of 25 nmol per cm2.2 (?)-Guaiol is also lethal to fourth instar M. separata and third instar P. xylostella larvae (LD50s  Group: Biochemicals. Alternative Names: 1,2,3,4,5 β, 6, 7, 8-Octahydro-α, α, 3α, 8α-tetramethyl-5-azulenemethanolGuai-1(5)-en-11-ol; Guaiol; (3S,5R,8S)-1,2,3,4,5,6,7,8-Octahydro-α,α,3,8-t. Grades: Highly Purified. CAS No. 489-86-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C??H??O, Molecular Weight: 222.37. US Biological Life Sciences. |  Worldwide |
| Guaiol | Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC 50 of 0.01 μg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Champacol; Guaiac alcohol. CAS No. 489-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N3980. |  |
| Guaiol Natural | Guaiol Natural. CAS No. 73003-40-4. Kosher: Y. VIGON Item # 508227. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils. |  America & Internationally |
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