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Guanosine triphosphate (GTP) is a guanine nucleotide containing three phosphate groups esterified to the sugar moiety. GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. Synonyms: D-Guanosine 5'-triphosphate; Guanosine triphosphate; Guanosine 5'-triphosphoric acid; pppG; guanosine 5'-O-(triphosphate); [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate. Grades: ≥98% by AX-HPLC. CAS No. 86-01-1. Molecular formula: C10H16N5O14P3. Mole weight: 523.18.
Guanosine 5'-triphosphate Disodium salt
Nucleotide used in the preparation of photoreactive GTP affinity probes, and in inhibitors of eukaryotic initiation factor eIF-4E. Group: Biochemicals. Alternative Names: 5-GTP·2Na; Guanosine 5-(tetrahydrogen triphosphate) disodium salt; 5-GTP di-Na salt; Disodium 5-GTP; Disodium guanosine triphosphate; GTP disodium salt; Guanosine 5-triphosphoric acid disodium salt. Grades: Purified. CAS No. 56001-37-7. Pack Sizes: 250mg, 500mg, 1g, 5g. Molecular Formula: C10H14N5O14P3Na2, Molecular Weight: 567.15. US Biological Life Sciences.
Worldwide
Guanosine 5'-triphosphate Sodium Salt
Guanosine-5'-triphosphate Disodium Salt is one the substances used in GTP affinity probe for proteomics highlights flexibility in purine nucleotide selectivity for the study of GTP-binding proteins.Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) is an activator of the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Group: Biochemicals. Alternative Names: GTP; Guanosine 5'-triphosphate sodium salt. Grades: Highly Purified. CAS No. 36051-31-7. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C10H13N5O14P3·xNa, Molecular Weight: 589.13 (Free Acid: 523.18). US Biological Life Sciences.
Worldwide
Guanosine 5'-triphosphate tetrasodium salt
Guanosine 5'-triphosphate tetrasodium salt is a paramount compound in the biomedical sector, serving as a pivotal precursor engendering diverse enzymatic reactions. Notably, it finds ubiquitous employment in research laboratories to elucidate G-protein coupled receptor signaling pathways, cellular energy transference and signal transduction mechanisms. Synonyms: Tetrasodium guanosine triphosphate; Guanosine 5'-(tetrasodium triphosphate); Tetrasodium 5'-O- ({[ (phosphonatooxy) phosphinato]oxy}phosphinato) guanosine; Guanosine, 5'-(tetrahydrogen triphosphate), sodium salt (1:4). Grades: ≥97% by HPLC. CAS No. 14356-96-8. Molecular formula: C10H12N5Na4O14P3. Mole weight: 611.11.
2'-3'-O-(4-Benzoylbenzoyl)guanosine 5'-triphosphate triethylammonium salt,Benzoylbenzoyl-GTP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Benzoylbenzoyl-GTP, 112898-14-3, 2 inverted exclamation marka-3 inverted exclamation marka-O-(4-Benzoylbenzoyl)guanosine 5 inverted exclamation marka-triphosphate triethylammonium salt. Product Category: Heterocyclic Organic Compound. CAS No. 112898-14-3. Molecular formula: NULL. Mole weight: 731.39. Purity: 0.96. IUPACName: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl 4-benzoyl-3-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]benzoate;N,N-diethylethanamine. Canonical SMILES: CCN(CC)CC.C1=CC=C(C=C1)C(=O)C2=C(C=C(C=C2)C(=O)OCC3C(C(C(O3)N4C=NC5=C4NC(=NC5=O)N)O)O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O. Product ID: ACM112898143. Alfa Chemistry ISO 9001:2015 Certified.
2-Amino-6-methoxy-2'-C-methylguanosine 5'-triphosphate triethylammonium salt
2-Amino-6-methoxy-2'-C-methylguanosine 5'-triphosphate triethylammonium salt, a remarkable chemical, unveils its unfathomable effects by unraveling the intricate mechanisms underlying RNA methylation, RNA splicing, and RNA modification. With a structural resemblance to guanosine triphosphate (GTP), this analog emerges as a pivotal tool fostering innovative research endeavors concerning the enigmatic domains of cancer biology and genetic disorders. Molecular formula: C12H20N5O14P3·C24H60N4. Mole weight: 955.99.
2'-Azido-2'-deoxyguanosine-5'-triphosphate lithium salt
2'-Azido-2'-deoxyguanosine-5'-triphosphate lithium salt, a cornerstone molecule employed in the field of biomedicine, holds immense significance. Its purpose lies in facilitating the introduction of the azido functional group into DNA chains through enzymatic synthesis. Consequently, this technique allows for precise identification of specific DNA segments, thereby aiding in diagnostics, gene expression analysis, comprehension of genetic alterations, and investigation of DNA-protein interplay. With its pivotal role in DNA sequencing and modification, this compound showcases unparalleled potential in advancing scientific research and discovery. Synonyms: 2'-Azido-2'-deoxy-D-guanosine-5'-triphosphate; 2'-Azido-dGTP. Grades: 90%. Molecular formula: C10H15N8O13P3. Mole weight: 548.19 (free acid).
2-C- β-Methyl Guanosine 5-Triphosphate is a derivative of 2-C- β-Methyl Guanosine (M311820) which is an anti-HCV agent. 2-C- β-Methyl Guanosine is an intermediate in the synthesis of novel double prodrug INX-08189, a new clinical candidate for hepatitis C virus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C11H18N5O12P3 xC6H15N, Molecular Weight: 505.21. US Biological Life Sciences.
Worldwide
2'-Deoxy-2'-fluoroguanosine-5'-triphosphate tetralithium salt
2'-Deoxy-2'-fluoroguanosine-5'-triphosphate tetralithium salt, a compound extensively utilized in the biomedical industry for nucleic acid research and diagnostics, stands as a vital reagent. Its significance lies in its role as a fundamental constituent in the synthesis of modified DNA strands, bolstered by the outstanding stability and nuclease resistance granted by its distinctive fluorine substitution. The manifold applications of this compound encompass drug discovery, genetic engineering, as well as investigations pertaining to antiviral agents. Synonyms: 2'-Deoxy-2'-fluoro-D-guanosine-5'-triphosphate. Grades: 95%. CAS No. 202186-97-8. Molecular formula: C10H15FN5O13P3·xLi. Mole weight: 525.17 (free acid).
2'-Deoxy-8-oxo-6-thioguanosine 5'-triphosphate
2'-Deoxy-8-oxo-6-thioguanosine 5'-triphosphate, a highly indispensable constituent in biomedical research, exhibits paramount significance as a substrate for enzymatic investigations and nucleotide analysis. Embellishing explorations into DNA damage response mechanisms, antiviral medication advancement, and the scrutiny of cancerous and other ailment-causing genetic mutations, this modified guanosine triphosphate analogue harbors substantial potential. Its unparalleled configuration and characteristic attributes render it an irreplaceable asset in the realm of comprehending nucleotide modifications and their repercussions on manifold cellular processes. Molecular formula: C10H16N5O13P3S. Mole weight: 539.24.
2'-Deoxyguanosine 3'-Monophosphate 5'-Triphosphate Triethylamine Salt
Deoxyguanosine 3'-Monophosphate 5'-Triphosphate is a derivative of 2'-Deoxyguanosine which is a nucleoside analog. Synonyms: 2'-Deoxy-guanosine 5'-(Tetrahydrogen triphosphate)? 3'-(Dihydrogen phosphate) Triethylamine Salt. Molecular formula: C10H17N5O16P4 xC6H15N. Mole weight: 587.16.
2'-O-(2-Methoxyethyl)guanosine 5'-triphosphate ammonium salt
2'-O-(2-Methoxyethyl)guanosine 5'-triphosphate ammonium salt is a vital recompound in research, allowing the modification of mRNA during the research and development of therapeutic proteins. This compound is instrumental in the development of innovative drugs targeting various diseases such as cancer, genetic disorders, and viral infections. Synonyms: (((2R,3R,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3-hydroxy-4-(2-methoxyethoxy)tetrahydrofuran-2-yl)methyl)triphosphoric ammonium salt. Molecular formula: C13H34N9O15P3. Mole weight: 649.38.
2'-O-Methylguanosine 5'-triphosphate
2'-O-Methylguanosine 5'-triphosphate is a vital biomolecule extensively utilized in diverse biomedical applications, serving as an essential substrate for RNA research and development and modification. Notably, this compound finding extensive application in research endeavors aimed at unraveling the intricate mechanisms underlying RNA metabolism, RNA splicing, and RNA editing. Synonyms: 2'-O-Methyl-GTP; 2'-O-methylguanosine 5'-(tetrahydrogen triphosphate); [[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate; 6H-Purin-6-one, 2-amino-1, 9-dihydro-9-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-2-O-methyl-b-D-ribofuranosyl]-; Guanosine 5'-(tetrahydrogen triphosphate), 2'-O-methyl-. Grades: ≥97% by HPLC. CAS No. 61556-44-3. Molecular formula: C11H18N5O14P3. Mole weight: 537.21.
2'-O-Methylguanosine-5'-triphosphate trilithium salt
2'-O-Methylguanosine-5'-triphosphate trilithium salt, a highly versatile compound, can be employed as an efficient probe for investigating RNA metabolism. It possesses the remarkable capability of obstructing RNA chain elongation, thus making it an invaluable research tool in the field. In addition to its chain terminating property, it also exhibits remarkable affinity with RNA-binding proteins and catalytic ribozymes, rendering it ideal for studying complex RNA-protein interactions and enzymatic activities. Synonyms: 2'-O-Me-GTP trilithium salt; Trilithium 5'-O-[ ({[ (hydroxyphosphinato) oxy]phosphinato}oxy) phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate. Grades: ≥97% by HPLC. Molecular formula: C11H15Li3N5O14P3. Mole weight: 555.00.
2'-O-Methylguanosine-5'-triphosphate trisodium salt
2'-O-Methylguanosine-5'-triphosphate trisodium salt is a nucleotide analog with diverse applications. Its use in RNA synthesis not only increases stability but also specificity for protein binding. When utilized as a probe, it is an invaluable tool for investigating RNA structure and function. Beyond such scientific applications, this compound also boasts potential therapeutic benefits when targeting viral diseases and cancer. Synonyms: 2'-O-Me-GTP trisodium salt; Trisodium 5'-O-[ ({[ (hydroxyphosphinato) oxy]phosphinato}oxy) phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), sodium salt (1:3); sodium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate. Grades: ≥97% by HPLC. Molecular formula: C11H15N5Na3O14P3. Mole weight: 603.15.
6-Thioguanosine-5'-O-triphosphate sodium salt
6-Thioguanosine-5'-O-triphosphate sodium salt, a pivotal compound extensively employed in biomedical research, serves as a guanosine triphosphate analog, exhibiting immense promise in combatting viral infections, leukemia, and autoimmune disorders. Its modus operandi revolves around integrating into RNA during transcription, thereby hindering RNA synthesis and thwarting viral replication. Synonyms: 6-T-GTP Na. Grades: ≥ 95%. Molecular formula: C10H16N5O13P3S·xNa. Mole weight: 539.25 (free acid).
7-Methylguanosine 5'-triphosphate sodium salt
7-Methylguanosine 5'-triphosphate sodium salt, a highly indispensable reagent in the field of biomedicine, finds extensive utilization across diverse applications. Functioning as a potent guanosine triphosphate (GTP) analogue, it assumes a pivotal role in the processes of mRNA capping, RNA processing, and RNA splicing. Its auxiliary role involves facilitating the exploration of RNA-protein interactions while also serving as a substrate for RNA methyltransferases. Molecular formula: C11H18N5O14P3·xNa. Mole weight: 537.21 (free acid).
7-Methylguanosine 5'-triphosphate sodium salt
7-Methylguanosine 5'-triphosphate sodium salt, a highly indispensable reagent in the field of biomedicine, finds extensive utilization across diverse applications. Functioning as a potent guanosine triphosphate (GTP) analogue, it assumes a pivotal role in the processes of mRNA capping, RNA processing, and RNA splicing. Its auxiliary role involves facilitating the exploration of RNA-protein interactions while also serving as a substrate for RNA methyltransferases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Methylguanosine 5-triphosphate sodium salt, 104809-18-9, M6133_SIGMA, CTK8E9676, 7-Methylguanosine 5 inverted exclamation marka-triphosphate sodium salt. Product Category: Heterocyclic Organic Compound. CAS No. 104809-18-9. Molecular formula: C11H18N5O14P3·xNa+. Mole weight: 537.21 (free acid basis). Purity: ≥85%. IUPACName: sodium;[[[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxido-3,6-dihydropurin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate. Product ID: ACM104809189. Alfa Chemistry ISO 9001:2015 Certified.
8-Hydroxy Guanosine 5'-Triphosphate Triethylammonium Salt
8-Hydroxy Guanosine 5'-Triphosphate is an oxidized ribonucleotide cDNA induced mutations, suggesting disturbance of genetic information during transcription and/or reverse transcription. It is a potential antiviral drug that causes mutations in genomic RNA. Synonyms: 7,8-Dihydro-8-oxoguanosine 5'-(Tetrahydrogen Triphosphate) Triethylammonium Salt; 2-Amino-9-β-D-ribofuranosylpurine-6,8(1H,9H)-dione 5'-(Tetrahydrogen Triphosphate) Triethylammonium Salt; 8-Ketoguanosine 5'-Triphosphate Bis(triethylammonium) Triethylammonium Salt; 8-OH-GTP Di-TEA Triethylammonium Salt. Grades: 95%. Molecular formula: C10H16N5O15P3 xNEt3. Mole weight: 539.18.
8-Oxo-2'-deoxyguanosine 5'-Triphosphate Triethylamine Salt
8-Oxo-2'-deoxyguanosine-5'-Triphosphate, considered mutagenic dNTPs, it can be incorporated into DNA by PCR using standard Taq polymerase. Synonyms: 2'-Deoxy-7,8-dihydro-8-oxo-guanosine 5'-(tetrahydrogen triphosphate) Triethylamine Salt; 8-Hydroxy-2'-deoxyguanosine 5'-triphosphate Triethylamine Salt; 8-Oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate Triethylamine Salt; 8-Oxo-dGTP Triethylamine Salt; 8-Oxo-deoxyguanosine triphosphate Triethylamine Salt. Molecular formula: C10H16N5O14P3 xC6H15N. Mole weight: 523.18.
Guanosine-13C10,15N5 5?-triphosphate sodium salt solution
?98 atom %, ?95% (CP), 100 mM in 5 mM Tris HCl. Group: Fluorescence/luminescence spectroscopy.
Guanosine-13C10 5?-triphosphate sodium salt solution
98 atom % 13C, 95% (CP), 100 mM in 5 mM Tris HCl. Group: Fluorescence/luminescence spectroscopy.
Guanosine-15N5 5?-triphosphate sodium salt solution
98 atom % 15N, 95% (CP), 100 mM in 5 mM Tris HCl. Group: Fluorescence/luminescence spectroscopy.
Guanosine 3'-diphosphate 5'-triphosphate
Guanosine 3'-diphosphate 5'-triphosphate is a pivotal molecule entwined in signal transduction and protein synthesis, emerging as an indispensable compound. It exert its prowess as an enthusiastic bestower of energy during translation, while adroitly orchestrating the activity of G-proteins. It assumes a role in unraveling the enigmatic dynamics of enzyme kinetics, nucleotide metabolism and the meticulous dissection of ailments synonymous to G-protein signaling cascades. Synonyms: Guanosine-3',5'-pentaphosphate; Guanosine pentaphosphate; pppGpp; Guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate); ( (2R, 3S, 4R, 5R) -5- (2-amino-6-oxo-1, 6-dihydro-9H-purin-9-yl) -4-hydroxy-3- ( (hydroxy (phosphonooxy) phosphoryl) oxy) tetrahydrofuran-2-yl) methyl tetrahydrogen triphosphate; 5'-Triphosphoguanosine 3'-diphosphate. Grades: ≥95%. CAS No. 38918-96-6. Molecular formula: C10H18N5O20P5. Mole weight: 683.14.
Also hydrolyses other guanosine 5'-triphosphate derivatives with at least one unsubstituted phosphate group on the 3'-position, but not GTP, ATP or adenosine 5'-triphosphate 3'-diphosphate. Group: Enzymes. Synonyms: pppGpp 5'-phosphohydrolase; guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase; guanosine pentaphosphatase; guanosine pentaphosphate phosphatase; guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase; guanosine pentaphosphate phosphohydrolase. Enzyme Commission Number: EC 3.6.1.40. CAS No. 85130-44-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4617; guanosine-5'-triphosphate,3'-diphosphate phosphatase; EC 3.6.1.40; 85130-44-5; pppGpp 5'-phosphohydrolase; guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase; guanosine pentaphosphatase; guanosine pentaphosphate phosphatase; guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase; guanosine pentaphosphate phosphohydrolase. Cat No: EXWM-4617.
Guanosine-5'-triphosphate?Na2-salt. Group: Coenzymes. Synonyms: GTP; Guanosine-5'-triphosphate?Na2-salt. CAS No. 56001-37-7. Purity: 0.92. Mole weight: 567.2. Appearance: White powder. Storage: -15 °C to -25 °C. coenzyme; Guanosine-5'-triphosphate?Na2-salt; GTP; 56001-37-7. Cat No: COEZ-003.
Guanosine-5'-triphosphate sodium salt
Guanosine-5'-triphosphate sodium salt could be used as a phosphoryl donor in signal transduction and protein synthesis. Synonyms: Guanosine 5'-(tetrahydrogen Triphosphate), Trisodium Salt; 5'-GTP Trisodium Salt; Trisodium 5'-GTP; GTP Trisodium Salt. Grades: ≥97% by HPLC. CAS No. 36051-31-7. Molecular formula: C10H13N5Na3O14P3. Mole weight: 589.13.
Guanosine-d14 5?-triphosphate disodium salt solution
?98 atom % D, ?95% (CP), 100 mM (in 5mM Tris / D2O). Group: Fluorescence/luminescence spectroscopy.
2'-Amino-2'-deoxyguanosine-5'-triphospate tetralithium salt
2'-Amino-2'-deoxyguanosine-5'-triphosphate tetralithium salt, a compound of utmost importance in the realm of biomedical research and drug discovery, exhibits its significance as a precursor for the synthesis of altered nucleotides, particularly employed in DNA and RNA sequencing. Its indispensable role in elucidating DNA methylation, epigenetic modifications, and mutagenesis studies across diverse ailments, encompassing cancer and genetic disorders, renders it a critical component. Synonyms: 2'-Amino-2'-deoxy-D-guanosine-5'-triphospate tetralithium salt. Grades: 95%. CAS No. 108269-13-2. Molecular formula: C10H17N6O13P3Li4. Mole weight: 549.96.
2'-Fluoro-ara-dGTP
2-Fluoro-ara-dGTP - an analogue of nucleoside - has been effectively utilized as a substrate for DNA polymerases in examining DNA replication and repair, and demonstrates potential in targeting specific cancer types, such as lymphoma and leukemia. Its capacity to cause strand termination when integrated into DNA during replication is a promising trait for the treatment of these diseases through chemotherapy. Synonyms: (2'F-ara-dGTP); 2'-Fluoro-2'-deoxy-ara-guanosine-5'-triphosphate, Tetralithium salt; 2'-Fluoro-2'-deoxy-arabinofuranosyl-guanine-5'-triphosphate; 2'-F-ara-2'-dGTP. Grades: ≥ 95% by HPLC. Molecular formula: C10H15FN5O13P3 (free acid). Mole weight: 525.17 (free acid).
2'-Fluoro-dGTP
2'-Fluoro-dGTP is a deoxyguanosine analog. Synonyms: 2'-Fluoro-2'-deoxyguanosine-5'-triphosphate; 2'-deoxy-2'-fluoroguanosine triphosphate; 2'-Fluoro-2'-deoxyguanosine 5'-triphosphoric acid; 2'-Deoxy-2'-fluoroguanosine 5'-(tetrahydrogen triphosphate); Guanosine, 2'-deoxy-2'-fluoro-, 5'-(tetrahydrogen triphosphate); 2'F-dGTP. Grades: ≥95% by HPLC. Molecular formula: C10H15FN5O13P3. Mole weight: 525.17.
3'-dGTP
3'-dGTP, a nucleotide analog extensively employed in DNA and RNA molecule synthesis, is a multi-utility molecule with its applications extending to DNA replication and repair mechanisms, treating viral infections, and cancer. With its ability to act as a molecular probe, 3'-dGTP becomes a fascinating choice for exploring protein-nucleic acid interactions. Synonyms: 3'-Deoxyguanosine-5'-Triphosphate; Guanosine 5'-(tetrahydrogen triphosphate), 3'-deoxy-. Grades: ≥95% by AX-HPLC. CAS No. 55968-37-1. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid).
3'-(O-Propargyl)-GTP
3'-(O-Propargyl)-GTP, a non-hydrolyzable GTP analog, is widely used in scientific research to examine the functions of GTPases in signal transduction and protein synthesis. Furthermore, it is renowned for its potential to detect prospective inhibitors of GTPase activity. This biochemical compound is indispensable to researchers and scholars alike, as its scientific applications hold tremendous promise for the advancement of molecular biology. Synonyms: 3'-(O-Propargyl)-guanosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C13H18N5O14P3 (free acid). Mole weight: 561.23.
5'-O-Tosylguanosine
As an intermediate in the synthesis of Adenosine 5'-Triphosphate Disodium Salt, 5'-O-Tosylguanosine is a multifunctional nucleoside triphosphate used in cells as a coenzyme of intracellular energy transfer. Synonyms: Guanosine 5'-(4-Methylbenzenesulfonate); NSC 62628. CAS No. 39947-33-6. Molecular formula: C17H19N5O7S. Mole weight: 437.43.
5'-Tosyl-2'-deoxy Guanosine
In the synthesis of α,β-methylene-2'-deoxynucleoside 5'-triphosphates, novel 2'-deoxycyclonucleosides are used as noncleavable substrates for DNA polymerases. Uses: A novel 2'-deoxycyclonucleosides. Synonyms: 5'-(4-Methylbenzenesulfonate) 2'-Deoxyguanosine. Grades: 95%. CAS No. 109954-64-5. Molecular formula: C17H19N5O6S. Mole weight: 421.43.
6-Chloro-GTP
6-Chloro-GTP is a highly significant compound, playing a pivotal role due to its exceptional antiviral attributes which effectively impede viral replication. By selectively targeting viral RNA research and development-associated enzymes, this remarkable compound showcasing an outstanding inhibitory effect. Promisingly, it finds extensive application in studying various viral infections like hepatitis C and respiratory syncytial virus (RSV). Synonyms: (6Cl-GTP); 6-Chloro-guanosine-5'-triphosphate, Sodium salt; 2-Amino-6-chloro-9-(β-D-ribofuranosyl)-purine. Grades: ≥ 95% by HPLC. Molecular formula: C10H15N5O13P3Cl (free acid). Mole weight: 541.62 (free acid).
6-Thio-GTP
6-Thio-GTP is a Vac-1-Rac signaling inhibitor that inhibits TNF-α-induced downstream signaling via JNK. It exhibits immunosuppressant effects. Uses: 6-thio-gtp is a vac-1-rac signaling inhibitor. Synonyms: 6-Thio-guanosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 17670-19-8. Molecular formula: C10H16N5O13P3S (free acid). Mole weight: 539.24 (free acid).
7-Deaza-2',3'-dideoxyguanosine
7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2',3'-dideoxynucleoside 5'-triphosphate, which can inhibit HIV-1 reverse transcriptase with a Ki of 25 nM. Synonyms: 2-Amino-7-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one; 7-Deaza-ddG; 2',3'-Dideoxy-7-Deazaguanosine; 7-Deaza-2',3'-dideoxy-D-guanosine; 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-3,7-dihydro-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-. Grades: ≥97% by HPLC. CAS No. 111869-49-9. Molecular formula: C11H14N4O3. Mole weight: 250.25.
8-[(6-Amino)hexyl]-amino-GTP
8-[(6-Amino)hexyl]-amino-GTP, a chemical component extensively utilized in the exploration of G proteins and signaling pathways, acts as an agonist for certain G protein-coupled receptors while also enhancing the binding of GTP to such receptors. Its role as a tool in the investigation of nucleotide exchange and regulatory mechanisms of G proteins cannot be contested. Fittingly, its indispensable contributions to scientific research have established it as a hallmark presence in academic and scientific pursuits. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3 (free acid). Mole weight: 637.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - 5/6-TAMRA
8-[(6-Amino)hexyl]-amino-GTP - 5/6-TAMRA is an indispensable compound in the biomedical sector, facilitating the observation and analysis of GTP-mediated phenomena. Enhancing the investigation of diseases such as cancer and neurodegenerative disorders, this compound, enriched with the 5/6-TAMRA moiety, empowers researchers in their pursuit of understanding the intricacies underlying GTP-binding proteins. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with 5/6-TAMRA, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C41H50N9O18P3 (free acid). Mole weight: 1049.81 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - 5-FAM
8-[(6-Amino)hexyl]-amino-GTP - 5-FAM is a fluorescently labeled biochemical compound commonly used in biomedical research. It is a modified form of Guanosine-5'-triphosphate (GTP) that contains a 5-carboxyfluorescein (5-FAM) dye molecule and an amino-hexyl spacer. This compound is especially valuable for studying GTP-binding proteins, nucleotide exchange assays and monitoring GTPase activity. Its fluorescence enables real-time visualization and quantification of GTP-related processes in drug discovery, cellular signaling and disease mechanisms. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with 5 FAM, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H40N7O20P3 (free acid). Mole weight: 995.68 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - 6-FAM
8-[(6-Amino)hexyl]-amino-GTP - 6-FAM is a compound with remarkable bioactivity serving as a fluorescent probe within nucleotide analogs. It facilitates the elucidation and monitoring of G-proteins and their intricate interplays in sundry physiological phenomena. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with 6 FAM, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H40N7O20P3 (free acid). Mole weight: 995.68 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - 6-JOE
8-[(6-Amino)hexyl]-amino-GTP - 6-JOE, a fluorescently-labeled analog of guanosine triphosphate (GTP), serves as a fundamental tool in biochemical research, enabling the exploration of GTP-binding proteins' function and activity. Additionally, this compound proves invaluable for detecting GTPase activity across a myriad of cellular processes. Its numerous applications cement its place as a critical component in any laboratory focused on biological experimentation. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with 6-JOE, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C39H41Cl2N6O23P3 (free acid). Mole weight: 1124.08 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - 6-ROX
8-[(6-Amino)hexyl]-amino-GTP - 6-ROX, a widely used fluorescent analog of guanosine triphosphate (GTP) in biomedical research, is a versatile compound that has become indispensable in in vitro diagnostics and the study of cell signaling and protein function. Its utility extends further to the investigation of G protein-coupled receptors, whose roles in devastating diseases such as Alzheimer's and cancer have become a primary focus. This remarkable product's intricate properties and astounding capabilities continue to leave researchers in awe. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with 6-ROX, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C49H58N9O18P3 (free acid). Mole weight: 1153.97 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-390
8-[(6-Amino)hexyl]-amino-GTP - ATTO-390, a fluorescent analog of guanosine triphosphate (GTP), is frequently utilized in the investigation of GTP-binding proteins, such as those involved in signal transduction and cell division. Not only is it crucial in the labeling and monitoring of these proteins, but also in the study of diseases like cancer where they hold significant importance. Its impact on the advancement of cellular research cannot be understated. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 390 Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C36H53N8O17P3 (free acid). Mole weight: 962.78 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-425
8-[(6-Amino)hexyl]-amino-GTP, branded as ATTO-425, boasts a multipurpose function as a fluorescent marker for observing the activity of GTP-binding proteins in biomedical research. With the high photostability of its ATTO-425 label, it renders high-resolution microscopy plausible for investigating protein localization and dynamics. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 425, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H55N8O19P3 (free acid). Mole weight: 1020.81 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-465
8-[(6-Amino)hexyl]-amino-GTP - ATTO-465 is a fluorescently-labeled GTP analog commonly used in biomedicine to study GTPases and their functions in signaling pathways. It can also be used to monitor the activity of various disease-related proteins, including those involved in cancer and neurological disorders. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 465, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C33H45N10O15P3 (free acid). Mole weight: 914.69 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-488
8-[(6-Amino)hexyl]-amino-GTP - ATTO-488 is a veritable gem used in advanced cell biology and drug discovery research. Specifically, it serves as an invaluable weapon to unravel the mysteries of G protein-coupled receptor (GPCR) signaling pathways. However, its use extends beyond mere identification as it also accurately monitors nucleotide exchange rates. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 488, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C41H51N10O23P3S2 (free acid). Mole weight: 1208.18 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-495
8-[(6-Amino)hexyl]-amino-GTP - ATTO-495 serves as a potent fluorescent probe to investigate the sub-cellular localization and functional dynamics of GTP-binding proteins within pathological environments. As such, this dynamic dye represents a valuable tool for elucidating the role of GTP-dependent pathways in disease states, including both degenerative and neoplastic conditions. With applications spanning multiple fields of biomedical research, this sophisticated probe facilitates a comprehensive understanding of molecular mechanisms underlying GTP metabolism. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 495, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H53N10O15P3 (free acid). Mole weight: 970.80 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-532
8-[(6-Amino)hexyl]-amino-GTP - ATTO-532 serving as an exemplary fluorescently labeled guanosine triphosphate (GTP) derivative exclusively employed as a quintessential probe for scrutinizing nucleotide binding studies and a remarkable marker for GTPase activity. Its spectroscopic highlight lies in its vivid green fluorescence emission, making it an unparalleled investigative instrument for visualizing GTP-dependent procedures in vivo as well as monitoring intricate protein interactions. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 532, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C45H59N10O23P3S2 (free acid). Mole weight: 1264.24 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-540Q
8-[(6-Amino)hexyl]-amino-GTP - ATTO-540Q is a cutting-edge fluorescent probe employed for studying cellular signaling pathways, specifically for investigating GTPase-dependent processes. This powerful tool enables the visualization and monitoring of GTPase activity. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 540Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 540Q (free acid). Mole weight: 1177.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-550
8-[(6-Amino)hexyl]-amino-GTP - ATTO-550, a fluorescent probe, intricately investigates the behavior of GTP-binding proteins. Its high level of purity distinguishes it, as it magnifies detection and monitoring of the activities of GTP-binding proteins such as Ras, Rho, and Rab family proteins. Additionally, it serves to track cell signaling pathways and evaluate the response of drugs for diseases, including but not limited to cancer, cardiovascular, and neurological disorders. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 550, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 550 (free acid). Mole weight: 1212.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-565
8-[(6-Amino)hexyl]-amino-GTP - ATTO-565 is a renowned and widely acknowledged fluorescent dye, conveniently tackling the task of labeling and tracking nucleotides, proteins and DNA. The amalgamation of its high photon yield and remarkable photo-stability renders it an indispensable compound in fluorescence microscopy, flow cytometry and other imaging techniques. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 565, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H58N9O18P3 (free acid). Mole weight: 1129.94 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-580Q
8-[(6-Amino)hexyl]-amino-GTP - ATTO-580Q, a highly versatile fluorescent probe, has become an indispensable tool in biochemical research, particularly in investigating intricate signal transduction pathways and identifying potential drug modulators for G protein-coupled receptors (GPCRs) activation. Its outstanding potency and selectivity in monitoring the said activation, coupled with its unique Atto-580Q labeling system, make it an ideal addition to any laboratory's assay toolbox. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 580Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 580Q (free acid). Mole weight: 1313.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-590
8-[(6-Amino)hexyl]-amino-GTP - ATTO-590 is a fluorescent nucleotide analog commonly used in biomedical research serving as a vital tool for studying cellular processes involving GTP and its derivatives. This compound enables visualization and tracking of GTP-binding proteins. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 590, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H67N9O18P3 (free acid). Mole weight: 1211.08 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-594
8-[(6-Amino)hexyl]-amino-GTP - ATTO-594 is a multifaceted fluorescent probe embodying an array of applications for biomedical research. It bears the unique ability to detect nucleotide binding and hydrolysis alongside small molecule-GTPase interactions. With its unparalleled power to illuminate the dynamic activities of GTPases engaged in cell signaling pathways, this fluorescent probe stands as a formidable asset to cellular explorations. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 594, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 594 (free acid). Mole weight: 1424.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-612Q
8-[(6-Amino)hexyl]-amino-GTP - ATTO-612Q is a fluorescently labeled analog of GTP, commonly used in biomedical research to study the activity of GTP-binding proteins involved in cell signaling pathways. Its strong fluorescence enables the visualization and quantification of such proteins in vitro and in vivo experiments. Additionally, this product is also utilized for the screening of compounds that target GTP-dependent signaling pathways, particularly those involved in cancer and developmental disorders. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 612Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 612Q (free acid). Mole weight: 1309.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-620
8-[(6-Amino)hexyl]-amino-GTP - ATTO-620 is an indispensable compound assuming a pivotal role in the fluorescent labeling procedure pertaining to proteins engaged in the intricate web of cellular metabolism. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 620, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 620 (free acid). Mole weight: 1130.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-633
8-[(6-Amino)hexyl]-amino-GTP - ATTO-633 is a cutting-edge fluorescent label widely utilized in the realm of biomedical research. Its exceptional light absorption and emission characteristics render it exceptionally suitable for real-time visualization of GTP-binding molecules, thereby facilitating the comprehensive examination of GTP-mediated processes across diverse biological systems. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 633, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 633 (free acid). Mole weight: 1170.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-647N
8-[(6-Amino)hexyl]-amino-GTP - ATTO-647N is a fluorescent nucleotide analog used in biochemical and biomedical research to study GTPase activities and signaling pathways. Its high fluorescent intensity and photostability make it ideal for live cell imaging and superresolution microscopy. This product is particularly useful in studying neurological disorders, including Alzheimer's and Parkinson's diseases. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 647N, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 647N (free acid). Mole weight: 1264.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-655
8-[(6-Amino)hexyl]-amino-GTP - ATTO-655, a fluorescently labeled GTP analog, serves as a reliable tool for labeling and visualization of GTP-binding proteins in cellular imaging while also contributing to a better understanding of intracellular signaling pathways involving G-proteins. Its versatile utilization in various studies highlights its significance in scientific research. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 655, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 655 (free acid). Mole weight: 1146.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-665
8-[(6-Amino)hexyl]-amino-GTP - ATTO-665, a fluorescent analog of GTP, functions as a critical resource for the investigation of GTP-binding proteins in cancer and neurological disease research. Its in vitro utilization enables the examination of GTPase enzyme dynamics, especially in their association with effector proteins. The product's existence enhances comprehension regarding the different GTP-controlled cellular events that participate in the progression of various diseases that afflict humanity. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 665, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 665 (free acid). Mole weight: 1241.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-680
8-[(6-Amino)hexyl]-amino-GTP - ATTO-680 is a fluorescent dye commonly used in biomedical research frequently employed for labeling and visualizing proteins, nucleic acids and small molecules in cellular imaging studies. With its excitation and emission wavelength at the red end of the spectrum is aTTO-680 is ideal for multiplex experiments. It supports various applications, including drug discovery, disease diagnosis and molecular biology research. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 680, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 680 (free acid). Mole weight: 1144.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-700
8-[(6-Amino)hexyl]-amino-GTP, a fluorescent compound, serves the poignant purpose of facilitating the monitoring of G protein-coupled receptor (GPCR) activation. This impeccable solution proves effective as it binds to the G protein alpha subunit, opening new avenues of research into diseases such as cancer, hypertension, and diabetes - all of which involve GPCRs as pivotal factors. This amalgamation of scientific specificity and medical application earns 8-[(6-Amino)hexyl]-amino-GTP a critical place in modern research. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 700, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 700 (free acid). Mole weight: 1184.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-740
ATTO-740 labeled 8-[(6-Amino)hexyl]-amino-GTP is a highly versatile fluorescent probe, extensively utilized in the field of biomedical research, primarily for the characterization of G-proteins and their functional activity. This powerful tool has also shown promising potential in the development of novel diagnostic assays for a diverse range of diseases, spanning from infectious diseases to cancer. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO 740, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O14P3- ATTO 740 (free acid). Mole weight: 1086.37 (free acid).
8-[(6-Amino)hexyl]-amino-GTP - ATTO-MB2
8-[(6-Amino)hexyl]-amino-GTP serves as a pivotal biomedicine product for exploring the nuances of G-protein functions and their interplay with enzymes. Remarkably, this entity proves indispensable for comprehending diseases like cancer, cardiovascular disease, and diabetes from a scientific lens. Furthermore, this molecule can be enriched with ATTO-MB2, a pioneering fluorescent label lending itself to versatile imaging and microscopy techniques to facilitate heightened understanding and study. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-5'-triphosphate, labeled with ATTO-MB2, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C35H49N10O15P3S (free acid). Mole weight: 974.81 (free acid).
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