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| Product | Description | |
|---|---|---|
| GYKI 47261 dihydrochloride | GYKI 47261 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1217049-32-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| GYKI 47261 dihydrochloride | This active molecular is Non-competitiv a AMPA antagonist with IC50 value of 2.5 μM. GYKI-47261 is also a CYP2E1 inducer. GYKI-47261 showed broad spectrum of anticonvulsive and really good neuroprotective effect in vivo. AMPA and NMDA receptors have been implicated in the regulation of corticostriatal synaptic efficacy which abundantly expressed on striatal medium spiny neurons. In 2000, preclinical development for Epilepsy in Hungar was on-going, but no development was reported yet. Uses: Epilepsy; parkinson's disease; stroke. Synonyms: GYKI 47261 dihydrochloride; GYKI47261 dihydrochloride; GYKI-47261 dihydrochloride; 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)aniline;dihydrochloride;220445-20-5 (free base). Grades: 98%. CAS No. 1217049-32-5. Molecular formula: C18H17Cl3N4. Mole weight: 395.71. |  |
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