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| Product | Description | |
|---|---|---|
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride, a muscle relaxant and anticonvulsant agent with good blood-brain barrier permeability, is a potent, selective, orally active and non-competitive antagonist of kainate- and AMPA-activated currents with IC50s of 7.5 and 11 μM, respectively. It has no activity against N-methyl-D-aspartate (NMDA) or γ-aminobutyric acid responses. Synonyms: 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenamine dihydrochloride; Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:2). Grade: ≥95%. CAS No. 2319722-40-0. Molecular formula: C17H17Cl2N3O2. Mole weight: 366.24. |  |
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 102771-26-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride is an orally active, highly selective and noncompetitive AMPA/kainate receptor antagonist with the IC 50 values of 7.5 and 11μM, respectively. GYKI 52466 dihydrochloride has good blood brain barrier permeability and anticonvulsant effect. GYKI 52466 dihydrochloride can be used in Parkinson's disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2319722-40-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103234A. |  |
| GYKI 52466 hydrochloride | GYKI 52466 hydrochloride, a muscle relaxant and anticonvulsant agent with good blood-brain barrier permeability, is a potent, selective, orally active and non-competitive antagonist of kainate- and AMPA-activated currents with IC50s of 7.5 and 11 μM, respectively. It has no activity against N-methyl-D-aspartate (NMDA) or γ-aminobutyric acid responses. Synonyms: 4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline hydrochloride; 1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride; Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:1). Grade: ≥95%. CAS No. 192065-56-8. Molecular formula: C17H16ClN3O2. Mole weight: 329.78. | |
| GYKI 52466 hydrochloride | solid. Group: Fluorescence/luminescence spectroscopy. |  |
| GYKI 52466 Hydrochloride (1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride, GYKI-52,466, GYK I52466) | A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 10-20uM) over kainate (IC50 ~450uM) and nMDA (IC50 >> 50uM) receptors. Commonly used as neuroprotectant, anticonvulsant, and skeletal muscle relaxant. Biologically viable admitted orally or systematically. Group: Biochemicals. Grades: Highly Purified. CAS No. 102771-26-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GYKI-52466 | GYKI-52466 is a non-competitive AMPA receptor antagonist. It belongs to 2,3-benzodiazepine that acts as an ionotropic glutamate receptor antagonist. It has anticonvulsant and neuroprotective properties. It is an orally-active anticonvulsant and skeletal muscle relaxant. It also was found to have therapeutic potential for cocaine addiction treatment. Uses: Gyki-52466 is an orally-active anticonvulsant and skeletal muscle relaxant. it also was found to have therapeutic potential for cocaine addiction treatment. Synonyms: 4-(8-Methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline; GYKI-52466; GYKI52466; GYKI 52466; GYKI-5,2466; GYKI52,466; GYKI 52,466. Grade: >99 %. CAS No. 102771-26-6. Molecular formula: C17H15N3O2. Mole weight: 293.33. | |
| 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine. | 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine. Group: Biochemicals. Alternative Names: 9H-1,3-Dioxolo[4,5-h][2,3]benzodiazepine Benzenamine deriv; GYKI 52466. Grades: Highly Purified. CAS No. 102771-26-6. Pack Sizes: 10mg. Molecular Formula: C17H15N3O2, Molecular Weight: 293.32. US Biological Life Sciences. | Worldwide |
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