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| Product | Description | |
|---|---|---|
| GYKI 53655 hydrochloride | GYKI 53655 hydrochloride is a non-competitive AMPA and kainate receptor antagonist displaying anticonvulsant activity. It also acts as a blocker of GluK3 homomeric receptors (IC50 = 63 μM) and GluK2b(R)/GluK3 heteroreceptors (IC50 = 32 μM) at high concentrations. GYKI 53655 prolongs the survival time after MgCl2- induced global cerebral ischemia. Synonyms: GYKI53655 Hydrochloride; GYKI53655 HCl; GYKI53655; GYKI 53655; GYKI-53655. LY 300168 hydrochloride; LY300168 hydrochloride; LY-300168 hydrochloride; 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride; 5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 143692-48-2. Molecular formula: C19H20N4O3.HCl. Mole weight: 388.85. |  |
| GYKI 53655 hydrochloride | GYKI 53655 (LY300168) hydrochloride is an α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid ( AMPA ) antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY300168 hydrochloride. CAS No. 143692-48-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103228. |  |
| GYKI 53655 Hydrochloride | A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 6 and 5uM for GluA1 and GluA4, respectively) over kainate receptors (IC50 = 63 and 32uM for GluK3 and GluK2b/GluK3 receptors. Used as neuroprotectant and anticonvulsant, and a valuable tool for the study of AMPA receptor-mediated processes in vivo. Group: Biochemicals. Alternative Names: LY 300168, GYKI-53655 Hydrochloride, AMPA Glutamate Receptor Antagonist, GYKI 53655 Hydrochloride, 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride. Grades: Highly Purified. CAS No. 143692-48-2. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
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