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| Product | Description | |
|---|---|---|
| H-9 dihydrochloride | H-9 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 116700-36-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| H-9 dihydrochloride | H-9 dihydrochloride is a protein kinase inhibitor. It inhibits PKA (Ki = 1.9 μM), PKG (Ki = 0.9 μM), CaMK II (Ki = 60 μM), PKC (Ki = 18 μM), casein kinase I (Ki = 110 μ M) and casein kinase II (Ki > 300 μM). H-9 hydrochloride reduces the cAMP-mediated excitatory response to serotonin in C. elegans enteric neurons2 and inhibits PKA-mediated phosphorylation in a rat seizure model. Synonyms: H-9 dihydrochloride; H 9 dihydrochloride; H9 dihydrochloride; N-(2-Aminoethyl)-5-isoquinolinesulfonamide dihydrochloride. Grades: ≥99% by HPLC. CAS No. 116700-36-8. Molecular formula: C11H13N3O2S.2HCl. Mole weight: 324.22. |  |
| H-9 Dihydrochloride | H-9 Dihydrochloride is a PKA (protein kinase) inhibitor. H-9 Dihydrochloride (10 μM) significantly reduces the excitatory response to 5-HT. H-9 Dihydrochloride also has a direct effect on pharyngeal activity. H-9 Dihydrochloride inhibits signal-transduction and cell growth in EGF (epidermal growth factor)-dependent epithelial cell lines [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 116700-36-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100923. |  |
| Protein Kinase Inhibitor H-9 (PKI) (N- (2-aminoethyl ) -5-isoquinolinesulfonamid e dihydrochloride) | Competitive inhibitor of protein kinase C, cGMP- and cAMP-dependent protein kinases with respect to ATP binding. Group: Biochemicals. Alternative Names: N- (2-aminoethyl ) -5-isoquinolinesulfonamid e dihydrochloride. Grades: Molecular Biology Grade. CAS No. 84468-17-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 5-Hydroxy Topotecan Dihydrochloride Salt (Mixture of Diastereomers) | Dihydrochloride Salt of 5-Hydroxy Topotecan, is the metabolite of Topotecan (T542500), which is a DNA topoisomerase I inhibitor, semi synthetic analog of Camptothecin, and an antineoplastic. Group: Biochemicals. Alternative Names: (4S)-10-[ (Dimethylamino)methyl]-4-ethyl-4, 9, 12-trihydroxy-1H-Pyrano[3', 4': 6, 7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione Dihydrochloride Salt; 10-Hydroxy-9-[ (dimethylamino)methyl]-5-hydroxy- (20S, 5RS)-camptothecin Dihydrochloride Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| ALB 109564(a) dihydrochloride | ALB 109564(a) is a Tubulin inhibitor as a semi-synthetic derivative of the vinka alkaloid originated by AMRI. It can bind to tubulin monomers and inhibit microtubule formation, this leads to the disruption of mitotic spindle assembly and arrest of tumor cells in the G2/M phase of the cell cycle. Phase I clinical trials for Solid tumours is on going. Uses: Solid tumours. Synonyms: ALB-109564 dihydrochloride; ALB 109564 dihydrochloride; ALB109564 dihydrochloride; Vincaleukoblastine 12(methylthio) hydrochloride (1:2);(3aR,3a1R,4R,5S,5aR,10bR)-methyl 4-acetoxy-3a-ethyl-9-((3S,5S,7S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-13-(methylthio)-2,4,5,6,7,8,9,10-octahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate. Grades: 98%. CAS No. 1300114-12-8. Molecular formula: C47H60N4O9S. Mole weight: 930.00. | |
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