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H3B-6527 H3B-6527 is an orally active, highly selective and covalent FGFR4 inhibitor with an IC 50 of <1.2 nM. H3B-6527 has at least 250-fold selectivity over FGFR1-3 with IC 50 s of 320 nM, 1290 nM and 1060 nM respectively. H3B-6527 has potent anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1702259-66-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100491. MedChemExpress MCE
H3B-6527 H3B-6527 is a potent, highly selective and orally active FGFR4 inhibitor with potential antineoplastic activity. Synonyms: N-{2-[ (6-{[ (2, 6-Dichloro-3, 5-dimethoxyphenyl)carbamoyl] (methyl)amino}-4-pyrimidinyl)amino]-5- (4-ethyl-1-piperazinyl)phenyl}acrylamide; H3B-6527; H3B 6527; H3B6527. CAS No. 1702259-66-2. Molecular formula: C29H34Cl2N8O4. Mole weight: 629.543. BOC Sciences 9

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