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| Product | Description | |
|---|---|---|
| HA-1004 | HA-1004 is a selective inhibitor of PKA, which can inhibit lipolysis and induce vascular relaxation. HA-1004 is also a dual inhibitor of cyclic GMP-dependent protein kinase and cyclic AMP-dependent protein, and is involved in smooth muscle, second messenger, cyclic AMP and cyclic GMP regulation mechanisms. HA-1004 is an antagonist for calcium , that can be used as a vasodilator to inhibit the contraction of rabbit aortic strips, or to antagonize ERK and tyrosine hydroxylase (TH) phosphorylation in morphine abstinence rat models [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 91742-10-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-123468. |  |
| HA-1004 dihydrochloride | HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein. Synonyms: 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, hydrochloride (1:2); 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, dihydrochloride; HA 1004 dihydrochloride; HA1004 dihydrochloride; N-(2-guanidinoethyl)-5-isoquinolinesulfonamide dihydrochloride. Grades: ≥98%. CAS No. 92564-08-4. Molecular formula: C12H15N5O2S.2HCl. Mole weight: 366.27. |  |
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