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Halofuginone hydrochloride Halofuginone hydrochloride. Group: Biochemicals. Alternative Names: rel-7-Bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone hydrochloride; 7-Bromo-6-chlorofebrifugine hydrochloride; HAL. Grades: Highly Purified. CAS No. 1217623-74-9. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C16H17BrClN3O3·HCl. US Biological Life Sciences. USBiological 7
Worldwide
Halofuginone Hydrochloride Halofuginone Hydrochloride is the hydrochloride salt preparation of Halofuginone. Synonyms: rel-7-Bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone Hydrochloride; 7-Bromo-6-chlorofebrifugine Hydrochloride; HAL. Grades: > 95%. CAS No. 1217623-74-9. Molecular formula: C16H18BrCl2N3O3. Mole weight: 451.15. BOC Sciences 6
Halofuginone Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-bromo-6-chloro-3-[3-[(2r,3s)-3-hydroxy-2-piperidyl]-2-oxopropyl]-4(3h)-quinazolinone;HALOFUGINONE;4(3h)-quinazolinone,7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropy;7-Bromo-6-chloro-3[3-(3-hydroxy-2-piperidi-nyl)-2-oxopropyl]-4(3H)-quinzolinone;trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)-4(3h)-qui;trans-l);7-Bromo-6-chloro-3-(3-(3-hydroxypiperidin-2-yl)-2-oxopropyl)quinazolin-4(3H)-one;7-Bromo-6-chlorofebrifugine Hydrochloride. Product Category: Inhibitors. Appearance: Solid. CAS No. 55837-20-2. Molecular formula: C16H17BrClN3O3. Mole weight: 414.68. Purity: 0.9978. Canonical SMILES: O=C1N(CC(C[C@@H]2NCCC[C@H]2O)=O)C=NC3=C1C=C(Cl)C(Br)=C3. Product ID: ACM55837202. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.

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