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It is a minor component produced from heparin by heparinase II. Synonyms: alpha-DeltaUA-2S-[1->4]-GlcNAc-6S; α-δUA-2S-[1->4]-GlcNAc-6S; D-Glucopyranose, 2-(acetylamino)-2-deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-, 6-(hydrogen sulfate), sodium salt (1:3); Trisodium 2-acetamido-2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-D-glucopyranose. Grades: ≥95%. CAS No. 136098-00-5. Molecular formula: C14H18NNa3O17S2. Mole weight: 605.39.
Heparin disaccharide I-H trisodium salt
It is the major component from the action of heparinase II on de-N-sulfated heparin. Synonyms: Heparin unsaturated disaccharide I-H trisodium salt; alpha-DeltaUA-2S-[1->4]-GlcN-6S; Trisodium 2-amino-2-deoxy-4-O-(4-deoxy-2-O-sulfonato-alpha-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-D-glucopyranose; 2-Amino-2-deoxy-4-O-(4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl)-D-glucose 6-(hydrogen sulfate) trisodium salt; α-δUA-2S-[1->4]-GlcN-6S. Grades: 95%. CAS No. 136098-04-9. Molecular formula: C12H16NNa3O16S2. Mole weight: 563.35.
Heparin disaccharide II-A disodium salt
It is a product of the action of heparinases II and III on heparin and heparin sulfate. Synonyms: Disodium 2-acetamido-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-D-glucopyranose; 2-(Acetylamino)-2-deoxy-4-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-D-glucose 6-(hydrogen sulfate) disodium salt. Grades: ≥95%. CAS No. 136098-06-1. Molecular formula: C14H19NO14SNa2. Mole weight: 503.34.
Heparin disaccharide II-H disodium salt
Heparin disaccharide II-H disodium salt is the major component from the action of heparinase II on de-N-sulfated heparin. Synonyms: Heparin unsaturated disaccharide II-H disodium salt; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-5-amino-4,6-dihydroxy-2-(sulfonatooxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylate; D-Glucopyranose, 2-amino-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-, 6-(hydrogen sulfate), sodium salt (1:2); Alpha-delta-ua-[1->4]-GlcN-6S sodium salt. Grades: ≥98%. CAS No. 136098-02-7. Molecular formula: C12H17NNa2O13S. Mole weight: 461.31.
Heparin disaccharide III-A disodium salt
It is a minor product of the action of heparinase II on heparin. Synonyms: Disodium 2-acetamido-2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-D-glucopyranose; 2-(Acetylamino)-2-deoxy-4-O-(4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl)-D-glucose disodium salt. Grades: ≥95%. CAS No. 136098-11-8. Molecular formula: C14H19NNa2O14S. Mole weight: 503.34.
Heparin disaccharide III-H disodium salt
It is the major component from the action of heparinase II on de-N-sulfated heparin. Synonyms: alpha-DeltaUA-2S-[1->4]-GlcN; α-δua-2s-[1?4]-glcn; Disodium 2-amino-2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-D-glucopyranose. Grades: ≥95%. CAS No. 136098-01-6. Molecular formula: C12H18NNaO13S. Mole weight: 439.33.
Heparin disaccharide III-S trisodium salt
It is produced from heparin by digestion with heparinase I and II. Synonyms: Alpha-delta-ua-2s-[1->4]-glcns sodium salt; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-4,6-dihydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)tetrahydro-2H-pyran-3-yloxy)-4-hydroxy-3-(sulfonatooxy)-3,4-dihydro-2H-pyran-6-carboxylate; Trisodium 2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfonatoamino)-D-glucopyranose. Grades: ≥95%. CAS No. 136098-03-8. Molecular formula: C12H16NNa3O16S2. Mole weight: 563.35.
Heparin disaccharide II-S trisodium salt
It is produced from heparinase II digestion of heparin and heparin sulphate. Synonyms: 2-Deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose 6-(Hydrogen sulfate) Trisodium Salt; Alpha-delta-ua-[1->4]-glcns-6S sodium salt; Trisodium 2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-2-(sulfonatoamino)-D-glucopyranose. CAS No. 136098-05-0. Molecular formula: C12H16NNa3O16S2. Mole weight: 563.35.
Heparin disaccharide I-P trisodium salt
It is prepared from heparin unsaturated disaccharide I-H by n-propionylation. It is a homologue of disaccharide I-A with the inclusion of a methylene group in the amide acyl group. It does not occur in nature and was devised as an internal standard for HPLC, CZE and CE analysis of heparin/heparin sulfate. It is also ideally suited as an internal standard for HLPC/CZE analysis of chondroitin series, after digestion with chondroitinases. Synonyms: Heparin unsaturated disaccharide I-P trisodium salt; (α-δUA-2S-[1?4]-GlcNCOEt-6S); 2-Deoxy-3-O-[(1R)-4-deoxyhex-4-enopyranuronosyl]-2-(propionylamino)-D-glycero-hexopyranose trisodium salt. Grades: 95%. CAS No. 149368-05-8. Molecular formula: C15H20NNa3O17S2. Mole weight: 619.42.
Heparin disaccharide I-S, tetrasodium salt
It is a predominant disaccharide produced from heparin by heparinase I and II. Synonyms: 2-Deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose 6-(hydrogen sulfate) Sodium Salt; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-4,6-dihydroxy-5-(sulfonatoamino)-2-(sulfonatooxymethyl)tetrahydro-2H-pyran-3-yloxy)-4-hydroxy-3-(sulfonatooxy)-3,4-dihydro-2H-pyran-6-carboxylate; alpha-DeltaUA-2S-[1->4]-GlcNS-6S; Tetrasodium 2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-2-(sulfonatoamino)-D-glucopyranose. Grades: ≥98%. CAS No. 136098-10-7. Molecular formula: C12H15NNa4O19S3. Mole weight: 665.40.
Heparin disaccharide IV-A, sodium salt
It is produced from heparin sulfate by digestion with heparinase III. Synonyms: ΔGlcAΔ(1-4)GlcNAc; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylate; D-Glucopyranose, 2-(acetylamino)-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-, sodium salt (1:1); α-δ-UA-[1->4]-GLCNAC. Grades: ≥90%. CAS No. 136098-07-2. Molecular formula: C14H20NNaO11. Mole weight: 401.30.
Heparin disaccharide IV-H
It is the product of digestion of heparin sulfate and heparin by various heparinases. Synonyms: alpha-delta-UA-[1->4]-GLCN; 2-Amino-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-D-glucose; D-Glucose, 2-amino-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-. Grades: 95%. CAS No. 123228-39-7. Molecular formula: C12H19NO10. Mole weight: 337.28.
Heparin disaccharide IV-S disodium salt
It is produced from heparin sulfate by digestion with heparinase III. Synonyms: Heparin unsaturated disaccharide IV-S, disodium salt; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-4,6-dihydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)tetrahydro-2H-pyran-3-yloxy)-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylate; 2-Deoxy-4-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose disodium salt. Grades: ≥90%. CAS No. 136098-08-3. Molecular formula: C12H17NNa2O13S. Mole weight: 461.31.
Heparin derived disaccharide sodium salt
Heparin derived disaccharide sodium salt is a biomedical product used in the research of blood clotting disorders. This sodium salt compound is derived from heparin, a drug commonly used to prevent and study deep vein thrombosand pulmonary embolism. Synonyms: 2-Deoxy-2-sulfoamino-6-O-sulfo-4-O-(2-O-sulfo-a-L-idopyranuronosyl)-a-D-glucopyranose; 4-O-(a-L-Idopyranosyluronic acid 2-sulfate)-D-glucosamine 2,6-disulfate. CAS No. 98797-50-3. Molecular formula: C12H15NO19S3 Na4. Mole weight: 665.4.
1,2-O-Isopropylidene-β-L-idofuranuronic Acid 5-o-Pivaloate 6,3-Lactone is an intermediate in the synthesis of heparin-like disaccharides. Synonyms: 1,2-O-(1-Methylethylidene)-β-L-Idofuranuronic Acid γ-Lactone 5-(2,2-Dimethylpropanoate). CAS No. 243982-76-5. Molecular formula: C14H20O7. Mole weight: 300.3.
2,5-Anhydro-4-O-α-L-idopyranuronosyl-D-mannose 1-[(4-Nitrophenyl)hydrazinyl)methyl)] 6-(Hydrogen sulfate) is the fluorescent labelled hydrazine analogue of 2,5-Anhydro-4-O-α-L-idopyranuronosyl-D-mannose 1-[(4-Nitrophenyl)hydrazone] 6-(Hydrogen sulfate), a disaccharide related compound isolated from the deamination of heparin. Molecular formula: C18H25N3O15S. Mole weight: 555.47.
2,5-Anhydro-4-O-α-L-idopyranuronosyl-D-mannose 1-[(4-Nitrophenyl)hydrazone] 6-(Hydrogen sulfate) is the fluorescent labelled analogue of a disaccharide isolated from the deamination of heparin. Synonyms: 2,5-Anhydro-4-O-alpha-L-idopyranuronosyl-D-mannose 1-[(4-Nitrophenyl)hydrazone] 6-(Hydrogen sulfate). CAS No. 208049-20-1. Molecular formula: C18H23N3O15S. Mole weight: 553.45.
2-O-Sulphatase from Flavobacterium heparinum
The 2-O-sulphatase acts on 2-O-sulphated ?4,5-unsaturated termini of disaccharides, tetrasaccharides, etc., produced by lyase action on a glycosaminoglycan. Group: Enzymes. Synonyms: 2-O-Sulphatase; Sulphatase. Enzyme Commission Number: EC 3.1.6.-. 2-O-Sulphatase. Mole weight: 41.8 kDa. Form: The enzyme is stabilised with 0.2% BSA, 0.22 um sterile-filtered and dispensed into sterile vials. To preserve high activity, the enzyme solution is stored frozen at -60°C and is supplied world-wide as a frozen solution. Source: Flavobacterium heparinum (ATCC 13125). 2-O-Sulphatase; Sulphatase. Cat No: NATE-1943.
?-4,5-Glycuronidase from Flavobacterium heparinum
The ?-4,5-Glycuronidase acts on the non-sulphated, unsaturated termini of disaccharides, tetrasaccharides, etc., produced either directly by lyase action on a glycosaminoglycan or by the action of the 2-O-sulphatase on an unsaturated disaccharide, tetrasaccharide, etc. Group: Enzymes. Synonyms: ?-4,5-Glycuronidase; Glycuronidase. Enzyme Commission Number: EC 3.2.1-. β-Glucosidase. Storage: Store frozen at -20 or below upon receipt. Avoid repeated freezethawing. Form: The enzyme is stabilised with 0.2% BSA, 0.22 um sterile-filtered and dispensed into sterile vials. To preserve high activity, the enzyme solution is stored frozen at -60°C and is supplied world-wide as a frozen solution. Source: Flavobacterium heparinum (ATCC 13125). ?-4,5-Glycuronidase; Glycuronidase. Cat No: NATE-1942.
Chondroitinase AC from Flavobacterium heparinum, Recombinant
Chondroitinase AC from Flavobacteriun heparinum is an eliminase that degrades chondroitin sulfates A and C, but not chondroitin sulfate B. The enzyme cleaves, via an elimination mechanism, both sulfated and non-sulfated polysaccharide chains that contain (1?4)-linkages between hexosamines and glucuronic acid residues. The reaction yields oligosaccharide products, mainly disaccharides, with unsaturated uronic acids that can be detected by UV spectroscopy at 232 nm. Applications: Chondroitinase ac was shown to inhibit melanoma invasion and proliferation, endothelial proliferation, and angiogenesis. chondroitinase ac, but not chondroitinase b, has also been shown t..., and protease activities. ChnAC. Activity: >200 units/mg protein. Appearance: Powder. Storage: Store the product at -20?C. When stored properly and unopened at -20?C, the enzyme has a recommended retest date of 2 years. After reconstitution, the product may be kept at 4?C for 4 days, but it is recommended to store the solution in working aliquots at -20 ?C. Form: The enzyme is supplied as a lyophilized powder containing potassium phosphate, NaCl, and a stabilizer. Source: E. coli. Species: Flavobacterium heparinum. chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC; 9047-57-8; EC 4.2.2.5. Cat No: NATE-1738.
Chondroitinase B from Flavobacterium heparinum, Recombinant
In enzymology, a chondroitin B lyase (EC 4.2.2.19) is an enzyme that catalyzes the chemical reaction:Eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (deltaUA-GalNAc-4S). This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The enzyme cleaves, via an elimination mechanism, polysaccharide chains containing 1-4 linkages between hexosamines and iduronic acid residues in dermatan sulfate (chondroit...preparation of di-and oligo-saccharides of dermatan sulfate. Group: Enzymes. Synonyms: Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Enzyme Commission Number: EC 4.2.2.19. CAS No. 52227-83-5. Purity: > 90 % by reversed phase HPLC analysis. ChonB. Mole weight: 54,779 Da. Activity: > 550 IU/mg (substrate: dermatan sulfate). Stability: Expiration is 30 months from manufacturing date, frozen at -70°C in aqueous buffers containing Sodium Chloride, Sodium Phosphate and Sucrose 5%. Source: Flavobacterium heparinum. Species: Flavobacterium heparinum. Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Pack: vial of 5 ug. Cat No: NATE-0130.
chondroitin-sulfate-ABC endolyase
This enzyme degrades a variety of glycosaminoglycans of the chondroitin-sulfate- and dermatan-sulfate type. Chondroitin sulfate, chondroitin-sulfate proteoglycan and dermatan sulfate are the best substrates but the enzyme can also act on hyaluronan at a much lower rate. Keratan sulfate, heparan sulfate and heparin are not substrates. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of...ous); chondroitin ABC lyase (ambiguous);chondroitin sulfate ABC lyase (ambiguous); ChS ABC lyase (ambiguous); chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I. Enzyme Commission Number: EC 4.2.2.20. CAS No. 9024-13-9. Chondroitinase ABC. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5096; chondroitin-sulfate-ABC endolyase; EC 4.2.2.20; 9024-13-9; chondroitinase (ambiguous); chondroitin ABC eliminase (ambiguous); chondroitinase ABC (ambiguous); chondroitin ABC lyase (ambiguous);chondroitin sulfate ABC lyase (ambiguous); ChS ABC lyase (ambiguous); cho
chondroitin-sulfate-ABC exolyase
This enzyme degrades a variety of glycosaminoglycans of the chondroitin-sulfate- and dermatan-sulfate type. Chondroitin sulfate, chondroitin-sulfate proteoglycan and dermatan sulfate are the best substrates but the enzyme can also act on hyaluronan at a much lower rate. Keratan sulfate, heparan sulfate and heparin are not substrates. The related enzyme EC 4.2.2.20, chondroitin-sulfate-ABC endolyase, has the same substrate specificity but produces a mixture of oligosaccharides of different sizes that are ultimately degraded totetra- and disaccharides. Both enzymes act by the removal of a relatively acidic C-5 proton of the uronic acid followed by the elimination of a 4-linked ...C lyase (ambiguous); chondroitin sulfate ABC exoeliminase; chondroitin sulfate ABC exolyase; ChS ABC lyase II. Enzyme Commission Number: EC 4.2.2.21. CAS No. 1000607-06-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5097; chondroitin-sulfate-ABC exolyase; EC 4.2.2.21; 1000607-06-6; chondroitinase (ambiguous); chondroitin ABC eliminase (ambiguous); chondroitinase ABC (ambiguous); chondroitin ABC lyase (ambiguous);chondroitin sulfate ABC lyase (ambiguous); ChS ABC lyase (ambiguous); chondroitin sulfate ABC exoeliminase; chondroitin sulfate ABC exolyase; ChS ABC lyase II. Cat No: EXWM-5097.
Dalteparin Sodium EP
low-molecular-mass heparin. Grades: EP. CAS No. 913079-23-9. Product ID: 4-00669. Mole weight: Mw 5600 - 6400. Purity: degree of sulphation is 2.0 to 2.5 per disaccharide unit. potency 110- 210 IU of anti-factor Xa activity/mg. anti-factor IIa activity 35- 100 IU/mg, ratio of anti-factor Xa activity to anti-factor IIa activity is 1.9 - 3.2. Properties: degree of sulphation is ~ 2 per disaccharide. Source : obtained by alkaline depolymerization of benzyl ester derivative of heparin from porcine intestinal mucosa.
Enoxaparin Sodium EP
low-molecular-mass heparin. Grades: EP. CAS No. 679809-58-6. Product ID: 4-00670. Mole weight: Mw 3800-5000. Purity: > 90 - 125 IU of anti-factor Xa activity/mg, ratio of anti-factor Xa activity to anti-factor IIa activity 3.3 - 5.3. Properties: degree of sulphation is about 2 per disaccharide unit. Source : obtained by nitrous acid depolymerisation of heparin from pork intestinal mucosa, followed by fractionation to eliminate selectively most of the chains with a molecular mass below 2000.
Involved in the biosynthesis of heparin and heparan sulfate. Some forms of the enzyme from human (particularly the enzyme complex encoded by the EXT1 and EXT2 genes) act as bifunctional glycosyltransferases, which also have the 4-β-glucuronosyltransferase (EC 2.4.1.225, N-acetylglucosaminyl-proteoglycan 4-β-glucuronosyltransferase) activity required for the synthesis of the heparan sulfate disaccharide repeats. Other human forms of this enzyme (e.g. the product of the EXTL1 gene) have only the 4-α-N-acetylglucosaminyltransferase activity. In Caenorhabditis elegans, the product of the rib-2 gene displays the activities of this enzyme as well as EC 2.4.1.223, glucuronosyl-galactosyl-proteoglycan 4-α-N-acetylglucosaminyltransferase. Group: Enzymes. Synonyms: α-N-acetylglucosaminyltransferase II glucuronyl-. Enzyme Commission Number: EC 2.4.1.224. CAS No. 336193-98-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2453; glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-α-N-acetylglucosaminyltransferase; EC 2.4.1.224; 336193-98-7; α-N-acetylglucosaminyltransferase II glucuronyl-N-acetylglucosaminylproteoglycan α-1,4-N-acetylglucosaminyltransferase. Cat No: EXWM-2453.
Heparinase
Heparinase (Heparinase I) degrades heparin to oligosaccharide or unsaturated disaccharide. Heparinase can be used in the preparation of low molecular weight heparin (LMWH) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Heparinase I. CAS No. 9025-39-2. Pack Sizes: 50 U. Product ID: HY-P2839.
Involved in the biosynthesis of heparin and heparan sulfate. Some forms of the human enzyme (particularly the enzyme complex encoded by the EXT1 and EXT2 genes) act as bifunctional glycosyltransferases, which also have the glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-α-N-acetylglucosaminyltransferase (EC 2.4.1.224) activity required for the synthesis of the heparan sulfate disaccharide repeats. Group: Enzymes. Synonyms: N-acetylglucosaminylproteoglycan β-1,4-glucuronyltransferase; heparan glucuronyltransferase II. Enzyme Commission Number: EC 2.4.1.225. CAS No. 145539-84-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2454; N-acetylglucosaminyl-proteoglycan 4-β-glucuronosyltransferase; EC 2.4.1.225; 145539-84-0; N-acetylglucosaminylproteoglycan β-1,4-glucuronyltransferase; heparan glucuronyltransferase II. Cat No: EXWM-2454.
Native Flavobacterium heparinum Chondroitinase AC
Chondroitinase AC from Flavobacterium heparinum is an enzyme that cleaves sulfated and non-sulfated polysaccharide chains with (1-4) linkages between hexosamines and glucuronic acid residues, by an elimination mechanism. The resulting oligosaccharide products are mainly disaccharides with unsatuRated uronic acids. Chondroitinase AC specifically degrades chondroitin sulfates A and C, but not chondroitin sulfate B (dermatan sulfate). Applications: Chondroitinase ac from creative enzymes has been used for the large scale preparation of glycosaminoglycan (gag) fractions during the study of structural and sequence motifs in dermatan sulfate. Group: Enzymes. Synonyms: EC 4.2.2.5; 9047-57-8; chondroitin AC lyase; chondroitinase; chondroitin sulfate lyase; chondroitin AC eliminase; chondroitin AC lyase; chondroitinase AC; ChnAC. Enzyme Commission Number: EC 4.2.2.5. CAS No. 9047-57-8. ChnAC. Activity: 0.5-1.5 units/mg solid (using chondroitin sulfate A as substrate, also cleaves chondroitin sulfate C). Storage: -20°C. Form: lyophilized powder. Source: Flavobacterium heparinum. EC 4.2.2.5; 9047-57-8; chondroitin AC lyase; chondroitinase; chondroitin sulfate lyase; chondroitin AC eliminase; chondroitin AC lyase; chondroitinase AC; ChnAC. Cat No: NATE-0126.
Native Flavobacterium heparinum Chondroitinase B
Chondroitinase B cleaves, via an elimination mechanism, polysaccharide chains containing 1-4 linkages between hexosamines and iduronic acid residues in dermatan sulfate (chondroitin B).The reaction yields oligosaccharide products (mainly disaccharides) containing unsaturated uronic acids which can be detected by UV spectroscopy at 232 nm. Applications: Research reagent (glycobiology, preparation of oligosaccharide libraries from dermatan sulfate).determination of contents of chondrotin sulfates by hplc. Group: Enzymes. Synonyms: Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Enzyme Commission Number: EC 4.2.2.19. CAS No. 52227-83-5. ChonB. Mole weight: 55 kDa. Activity: >200 IU/mg (substrate: dermatan sulfate). Stability: 12 months frozen at -20°C in aqueous buffers containing sodium phosphate and sucrose 5%. Source: Flavobacterium heparinum. Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Cat No: NATE-1950.
Native Flavobacterium heparinum Chondroitinase C
Chondroitinase C acts upon chondroitin sulfate C, releasing unsatuRated 6-sulfated disaccharides. The enzyme also acts on hyaluronic acid, producing unsatuRated nonsulfated disaccharides. The enzyme is strongly inhibited by NaCl, Fe2+, Co2+ and phosphate ions. Group: Enzymes. Synonyms: EC 4.2.2.x,; 60184-91-0; Chondroitinase C; Chondroitin C lyase. Enzyme Commission Number: EC 4.2.2.x. CAS No. 60184-91-0. Chondroitinase C. Activity: > 200 units/mg solid. Storage: -20°C. Form: lyophilized powder. Source: Flavobacterium heparinum. EC 4.2.2.x,; 60184-91-0; Chondroitinase C; Chondroitin C lyase. Cat No: NATE-0132.
unsaturated chondroitin disaccharide hydrolase
The enzyme releases 4-deoxy-4,5-didehydro D-glucuronic acid or 4-deoxy-4,5-didehydro L-iduronic acid from chondroitin disaccharides, hyaluronan disaccharides and heparin disaccharides and cleaves both glycosidic (1?3) and (1?4) bonds. It prefers the sulfated disaccharides to the unsulfated disaccharides. Group: Enzymes. Synonyms: UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Enzyme Commission Number: EC 3.2.1.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3864; unsaturated chondroitin disaccharide hydrolase; EC 3.2.1.180; UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Cat No: EXWM-3864.
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