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[(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonic Acid Diethyl Ester is a reactant used in the preparation of cytochalasin. Group: Biochemicals. Alternative Names: (E,E)-(4-Methyl-2,4-hexadienyl)-phosphonic Acid Diethyl Ester. Grades: Highly Purified. CAS No. 104701-95-3. Pack Sizes: 10mg. US Biological Life Sciences.
[2S-[2α,3 β,4 β (1E, 3E, 5S * ) ] ] -4- (6-Methoxy-1, 5-di methyl -6-oxo-1, 3-hexadienyl ) -3- (2-methoxy-2-oxoethyl ) -1, 2-pyrrolidinedicarboxyl ic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester is an intermediate in the synthesis of Domoic acid (D531300), an excitatory amino acid isolated from the red alga Chondria armata Okamura, Rhodomelaceae. Domoic acid shown to be responsible for amnesic shellfish poisoning associated with ingestion of certain cultured blue mussels. Group: Biochemicals. Grades: Highly Purified. CAS No. 81658-40-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C23H35NO8. US Biological Life Sciences.
It is produced by the strain of Corallococcus (Myxococcus) coralloides. It is a bacterial RNA synthase inhibitor, mainly resistant to gram-positive bacteria. Synonyms: [(E)-5-(4-Hydroxy-5-{(E)-2-methyl-4-[2-methyl-5-((1Z,4E)-1-methyl-hexa-1,4-dienyl)-tetrahydro-furan-2-yl]-but-3-enoyl}-6-oxo-6H-pyran-2-yl)-hex-1-enyl]-carbamic acid methyl ester; [5-[4-Hydroxy-3-[2-methyl-1-oxo-4-[tetrahydro-2-methyl-5-(1-methyl-1,4-hexadienyl)furan-2-yl]-3-butenyl]-2-oxo-2H-pyran-6-yl]-1-hexenyl]carbamic acid methyl ester. CAS No. 96717-74-7. Molecular formula: C30H41NO7. Mole weight: 527.65.
Crocacin B
It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Synonyms: [[(2Z,5Z)-6-[[(2E,4E,6S,7S,8R,9S,10E)-7,9-Dimethoxy-3,6,8-trimethyl-1-oxo-11-phenyl-2,4,10-undecatrienyl]amino]-1-oxo-2,5-hexadienyl]amino]acetic acid; 2-[6-((2E,4E,10E)(6S,7S,9S,8R)-7,9-Dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienoylamino)(2Z,5Z)hexa-2,5-dienoylamino]acetic acid. CAS No. 237425-37-5. Molecular formula: C30H40N2O6. Mole weight: 524.65.
Cyclogregatin
It is produced by the strain of Aspergillus panamensis. It has anti-bacterial and fungal activity, but its antibacterial and fungal activity is lower than polymyxin A. It inhibits airy ascites carcinoma with MIC of 10 μg/mL (Gregatin A is 2 μg/mL). Synonyms: 4H-Furo(2,3-b)pyran-3,4(2H)-dione, 2-(1,3-hexadienyl)-5,6-dihydro-2,6-dimethyl-. CAS No. 120167-25-1. Molecular formula: C15H18O4. Mole weight: 262.30.
Gelastatin A
It is produced by the strain of Westerdykella multispora F50733. It can inhibit the activity of leucinase A and the IC50 of leucinase A is 0.63 μmol/L. Synonyms: (all-E)-5-(2,4-Hexadienylidene)-5,6-dihydro-2-oxo-2H-pyran-3-propanoic acid. Grades: ≥98%. Molecular formula: C14H16O4. Mole weight: 248.27.
Sorrentanone
It is produced by the strain of Penicillium chrysogenu SC 13887. It has weak to moderate effect against Gram-positive and Gram-negative bacteria. Synonyms: 2,5-Cyclohexadiene-1,4-dione, 2-hydroxy-3,6-dimethyl-5-[(2E,4E)-1-oxo-2,4-hexadien-1-yl]-; 2,5-Cyclohexadiene-1,4-dione, 2-hydroxy-3,6-dimethyl-5-(1-oxo-2,4-hexadienyl)-, (E,E)-. CAS No. 165337-76-8. Molecular formula: C14H14O4. Mole weight: 246.26.
Sperabillin A
It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus, Streptococcus pyogenes and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 1.31, 8.13 and 67.2, respectively. Synonyms: L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[[(2E,4Z)-1-oxo-2,4-hexadien-1-yl]amino]-; L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[(1-oxo-2,4-hexadienyl)amino]-, (E,Z)-; Antibiotic TAN 749A. CAS No. 111337-86-1. Molecular formula: C15H27N5O3. Mole weight: 325.41.
Sperabillin B
It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus, Streptococcus pyogenes and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 0.35, 8.84 and 27.3, respectively. Synonyms: D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-((1-oxo-2,4-hexadienyl)amino)-, (E,Z)-; D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-[[(2E,4Z)-1-oxo-2,4-hexadienyl]amino]-; Antibiotic TAN 749B. CAS No. 111337-85-0. Molecular formula: C16H29N5O3. Mole weight: 339.43.
Sperabillin C
It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 12.5 and 50, respectively. Synonyms: L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[[(2E,4E)-1-oxo-2,4-hexadien-1-yl]amino]-; L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[(1-oxo-2,4-hexadienyl)amino]-, (E,E)-; Antibiotic TAN 749C. CAS No. 111337-84-9. Molecular formula: C15H27N5O3. Mole weight: 325.41.
Sperabillin D
It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 1.82 and 55.9, respectively. Synonyms: D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-[[(2E,4E)-1-oxo-2,4-hexadien-1-yl]amino]-; D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-((1-oxo-2,4-hexadienyl)amino)-, (E,E)-; Antibiotic TAN 749D. CAS No. 111465-40-8. Molecular formula: C16H29N5O3. Mole weight: 339.43.
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