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| Product | Description | |
|---|---|---|
| Higenamine hydrochloride | Higenamine hydrochloride is a selective LSD1 inhibitor ( IC 50 =1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Norcoclaurine hydrochloride. CAS No. 11041-94-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N2037A. |  |
| Higenamine Hydrochloride | Formula: Group: Biochemicals. Grades: Plant Grade. CAS No. 11041-94-4. Pack Sizes: 20mg. US Biological Life Sciences. |  Worldwide |
| Higenamine | Higenamine (Norcoclaurine), a β2-AR agonist with antioxidant capability, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine is also a α1-adrenergic receptor antagonist with hypotensive effect. is a selective LSD1 inhibitor ( IC 50 =1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine protects myocyte Apoptosis and ischemia/reperfusion (I/R) injury through selective activation of beta2-adrenergic receptor ( β2-AR ). Higenamine also reduces I/R-induced myocardial infarction in mice. Higenamine can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine can be used to study cancer, inflammation, cardiorenal syndrome and other diseases [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Natural products. Alternative Names: Norcoclaurine; Demethyl-Coclaurine. CAS No. 5843-65-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N2037. | |
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