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| Product | Description | |
|---|---|---|
| histamine N-methyltransferase | Histamine N-methyltransferase (HMT, HNMT) is an enzyme that in humans is encoded by the HNMT gene. Histamine N-methyltransferase is one of two enzymes involved in the metabolism of histamine, the other being diamine oxidase. Histamine N-methyltransferase catalyzes the methylation of histamine in the presence of S-adenosylmethionine (SAM) forming N-methylhistamine. Group: Enzymes. Synonyms: histamine 1-methyltransferase; histamine methyltransferase; histamine-methylating enzyme; imidazolemethyltransferase; S-adenosylmethionine-histamine N-methyltransferase. Enzyme Commission Number: EC 2.1.1.8. CAS No. 9029-80-5. HNMT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1981; histamine N-methyltransferase; EC 2.1.1.8; 9029-80-5; histamine 1-methyltransferase; histamine methyltransferase; histamine-methylating enzyme; imidazolemethyltransferase; S-adenosylmethionine-histamine N-methyltransferase. Cat No: EXWM-1981. |  |
| Amodiaquin dihydrochloride dihydrate | Amodiaquine, a 4-aminoquinoquinoline compound, is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent for more than 40 years. Uses: Antimalarial. Synonyms: AMODIAQUIN DIHYDROCHLORIDE; amodiaquin dihydrochloride dihydrate; AMODIAQUINE DIHYDROCHLORIDE; AMODIAQUINE HCL; AMODIAQUIN HYDROCHLORIDE; 4-[(7-CHLORO-4-QUINOLINYL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL DIHYDROCHLORIDE; 4-([7-chloro-4-quinolinyl]amino)-2-([diet. Grade: >98%. CAS No. 6398-98-7. Molecular formula: C20H28Cl3N3O3. Mole weight: 464.81. |  |
| Amodiaquine | Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC 50 of ~20 μM. Anti-inflammatory effect [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amodiaquin. CAS No. 86-42-0. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1322A. |  |
| Amodiaquine | Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-creso;4-((7-Chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresol;4-[(7-Chloro-4-quinolinyl)amino]-alpha-(diethylamino)-o-cresol;7-Chloro-4-(3-diethylaminomethyl-4-hydroxyphenylamino)quinoline;Amodia. Product Category: Inhibitors. Appearance: Cyrstalline Solid. CAS No. 86-42-0. Molecular formula: C20H22ClN3O. Mole weight: 355.86. Canonical SMILES: OC1=CC=C(NC2=CC=NC3=CC(Cl)=CC=C23)C=C1CN(CC)CC. Density: 1.258. Product ID: ACM86420. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Amodiaquine-d10 | Amodiaquine-d 10 is the deuterium labeled Amodiaquine. Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189449-70-4. Pack Sizes: 1 mg. Product ID: HY-B1322AS. | |
| Amodiaquine-d10 | Amodiaquine-d10 is the deuterium labeled Amodiaquine. Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino-d10)methyl]phenol; 4-[(7-Chloro-4-quinolyl)amino]-α-(diethylamino-d10)-o-cresol; Camochin-d10; Camoquin-d10; Camoquinal-d10; Camoquine-d10; Flavoquine-d10; Miaquin-d10; NSC 13453-10; SN-10751-d10. Product Category: Inhibitors. Appearance: Pale Yellow Solid. CAS No. 1189449-70-4. Molecular formula: C20H12D10ClN3O. Mole weight: 365.92. Purity: ≥97.0%. Canonical SMILES: ClC(C=C1)=CC2=C1C(NC3=CC(CN(C([2H])([2H])C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H])=C(C=C3)O)=CC=N2. Product ID: ACM1189449704. Alfa Chemistry ISO 9001:2015 Certified. | |
| Amodiaquine dihydrochloride | Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor with a K i of 18.6 nM. Amodiaquine dihydrochloride is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC 50 of ~20 μM. Anti-inflammatory effect [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amodiaquin dihydrochloride. CAS No. 69-44-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1322B. | |
| Metoprine | Metoprine (BW 197U) is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT [1] [2]. Metoprine is an antifolate and antitumor agent [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BW 197U. CAS No. 7761-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-129441. | |
| Metoprine | Metoprine (BW 197U) is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT. Metoprine is an antifolate and antitumor agent. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(3,4-Dichlorophenyl)-6-methyl-2,4-pyrimidinediamine; 2,4-Diamino-5-(3,4- dichlorophenyl)-6-methylpyrimidine; 2,4-Diamino-5-(3',4'-dichlorophenyl)- 6-methylpyrimidine; BW 197U; BW 50197; DDMP; Methodichlorophen; NSC 19494; NSC 7364; SK 5265; U 197. Product Category: Inhibitors. Appearance: Solid. CAS No. 7761-45-7. Molecular formula: C11H10Cl2N4. Mole weight: 269.13. Purity: 0.96. IUPACName: 5-(3,4-dichlorophenyl)-6-methylpyrimidine-2,4-diamine. Canonical SMILES: CC1=C(C(=NC(=N1)N)N)C2=CC(=C(C=C2)Cl)Cl. Density: 1.447g/cm³. Product ID: ACM7761457. Alfa Chemistry ISO 9001:2015 Certified. | |
| SKF 91488 dihydrochloride | SKF 91488 (Homodimaprit) dihydrochloride is a potent and noncompetitive histamine N-methyltransferase inhibitor with a K i value of 0.9 microM. SKF 91488 dihydrochloride inhibits the methylation of labeled histamine in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Homodimaprit dihydrochloride. CAS No. 68941-21-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100967. | |
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