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| Product | Description | |
|---|---|---|
| HMR 1556 | HMR 1556, a chromanol derivative, is a potent I Ks blocker with IC 50 s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 223749-46-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106369. |  |
| HMR 1556 | HMR 1556 is a potent and selective Iks channel blocker (IC50 = 10.5 and 34 nM in canine and guinea pig ventricular myocytes, respectively). It selectively inhibits IKs currents over IKr, IKI, Ito and L-type Ca2+ channel currents. HMR 1556 also exhibits weak activity at Kv11.1 Kv1.5, Kv1.3, Kir2.1 and HCN2 channel currents. HMR 1556 is used in the treatment of proarrythmia. Uses: The treatment of proarrythmia. Synonyms: HMR-1556; HMR 1556; HMR1556.N-[(3R,4S)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)-2H-1-benzopyran-4-yl]-N-methylmetanesulfonamide. Grades: ≥98% by HPLC. CAS No. 223749-46-0. Molecular formula: C17H24F3NO5S. Mole weight: 411.44. |  |
| HMR 1556 | Potent and selective Iks channel blocker (IC50 values are 10.5 and 34nM in canine and guinea pig ventricular myocytes respectively). Selectively inhibits IKs currents over IKr, IKI, Ito and L-type Ca2+ channel currents. Also has little or no effect on Kv11.1 Kv1.5, Kv1.3, Kir2.1 and HCN2 channel currents. Potentiates E-4031-induced arrhythmias in vivo. Group: Biochemicals. Alternative Names: N- [ (3R, 4S) -3, 4-Dihydro-3-hydroxy-2, 2-di methyl -6- (4, 4, 4-trifluorobutoxy) -2H-1-benzopyran-4-yl] -N- methyl metanesulfonamide. Grades: Highly Purified. CAS No. 223749-46-0. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
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