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Humulene. CAS No. 6753-98-6. Kosher: Y. VIGON Item # 508006. Categories: Speciality Ingrdients Suppliers, ?-humulene or ?-caryophyllene.
America & Internationally
Humulene
Humulene is a monocyclic sesquiterpene derived from farnesyl diphosphate and naturally found in clove, basil, hops, and cannabis sativa. Humulene has potential anti-inflammatory, anti-tumor, and anti-bacterial properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 6753-98-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C15H24. US Biological Life Sciences.
Worldwide
α-Humulene
α-Humulene is a main constituent of Tanacetum vulgare L. (Asteraceae) essential oil with anti-inflammation (IC 50 =15±2 μg/mL). α-Humulene inhibits COX-2 and iNOS expression [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Humulene; α-Caryophyllene. CAS No. 6753-98-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N6968.
Alpha Humulene
Clove trees are indigenous to the Maluku islands of Indonesia. Indonesia has been the dominant producer off clove buds and clove oil globally for decades. Indonesia is also the largest consumer of clove buds as a spice, which is primarily used in the kretek cigarette industry. It is due to this high demand for Clove Buds in the cigarette industry that farmers are using the remaining components (dry leaves, and stems/ claws) of the clove tree to produce clove oil its derivatives thereafter. Uses: Pharmaceuticals. Group: Plant Extracts. INCI Names: Alpha Humulene. Grades: INDUSTRIAL GRADE. CAS No. 6753-98-6. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: CL-460. Olfactive Profile: Earthy, woody, herbal, spicy. EC No: 229-816-7. Origin: Indonesia.
New Jersey
α-humulene 10-hydroxylase
Requires cytochrome P-450. The recommended numbering of humulene gives 10-hydroxy-α-humulene as the product rather than 8-hydroxy-α-humulene as used by the reference. See Section F: Natural Product Nomenclature. Group: Enzymes. Synonyms: CYP71BA1. Enzyme Commission Number: EC 1.14.13.150. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0750; α-humulene 10-hydroxylase; EC 1.14.13.150; CYP71BA1. Cat No: EXWM-0750.
α-humulene synthase
The enzyme from Zingiber zerumbet, shampoo ginger, also gives traces of β-caryophyllene. Group: Enzymes. Synonyms: ZSS1. Enzyme Commission Number: EC 4.2.3.104. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5115; α-humulene synthase; EC 4.2.3.104; ZSS1. Cat No: EXWM-5115.
Gamma-humulene synthase (EC 4.2.3.56) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (gamma-humulene-forming). Group: Enzymes. Synonyms: humulene cyclase. Enzyme Commission Number: EC 4.2.3.56. CAS No. 110639-19-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5216; γ-humulene synthase; EC 4.2.3.56; 110639-19-5; humulene cyclase. Cat No: EXWM-5216.
α-guaiene synthase
Requires Mg2+. The enzyme from Pogostemon cablin gives 13% α-guaiene as well as 37% (-)-patchoulol (see EC 4.2.3.70), 13% Δ-guaiene (see EC 4.2.3.93), and traces of at least ten other sesquiterpenoids. In Aquilaria crassna three clones of the enzyme gave about 80% Δ-guaiene and 20% α-guaiene, with traces of α-humulene. A fourth clone gave 54% Δ-guaiene and 45% α-guaiene. Group: Enzymes. Synonyms: PatTps177 (gene name). Enzyme Commission Number: EC 4.2.3.87. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5250; α-guaiene synthase; EC 4.2.3.87; PatTps177 (gene name). Cat No: EXWM-5250.
amorpha-4,11-diene synthase
Requires Mg2+ and Mn2+ for activity. This is a key enzyme in the biosynthesis of the antimalarial endoperoxide artemisinin. Catalyses the formation of both olefinic [e.g. amorpha-4,11-diene, amorpha-4,7(11)-diene, γ-humulene and β-sesquiphellandrene] and oxygenated (e.g. amorpha-4-en-7-ol) sesquiterpenes, with amorpha-4,11-diene being the major product. When geranyl diphosphate is used as a substrate, no monoterpenes are produced. Group: Enzymes. Synonyms: amorphadiene synthase. Enzyme Commission Number: EC 4.2.3.24. CAS No. 259213-60-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5181; amorpha-4,11-diene synthase; EC 4.2.3.24; 259213-60-0; amorphadiene synthase. Cat No: EXWM-5181.
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