Hydrolase Suppliers USA
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Product | Description | |
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Cancer Hydrolase KIAA1363 Inhibitor, JW480 (2-Isopropylphenyl-2- (2-naphthyl) ethylcarbamate, AADACL1 Inhibitor, Arylacetamide Deacetylase-Like 1 Inhibitor, NCEH1 Inhibitor, Neutral Cholesterol Ester Hydrolase 1 Inhibitor) Quick inquiry Where to buy Suppliers range | A membrane-permeable, highly potent and selective inhibitor against the 2-acetyl MAGE (monoakylglycerol ether) hydrolase KIAA1363/AADACL1 of both human (IC50=12nM; PC3 lysate) and murine (IC50=20nM; brain membrane samples) origin, with no significant effect toward other PC3 or murine brain serine hydrolase activities, including HSL, FAAH, and AChE. Readily crosses blood-brain barrier in mice and effectively suppresses PC3-derived tumor growth in mice in vivo (by 56% on day 33; 80mg/kg/day; o.g.). Also inhibits blood carboxylesterase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
FAAH Inhibitor III, URB937 (Cyclohexylcarbamic acid-(3-carbamoyl-6-hydroxybiphenyl-3-yl)ester, Fatty Acid Amide Hydrolase Inhibitor III, URB937, Cyclohexylcarbamic acid-carbamoyl hydroxybiphenyl-3-yl) ester) Quick inquiry Where to buy Suppliers range | A blood-brain-barrier impermeable p-hydroxyphenylcarbamate compound that acts as a potent and irreversible inhibitor of FAAH activity (IC50 = 26.8nM rat brain) with excellent selectivity over monoacylglycerol lipases (IC50 > 100uM). Shown to rapidly block mouse liver FAAH activity over brain (ED50 = 0.2mg/kg vs. 40mg/kg, s.c.), elevate anandamide and palmitoylethanolamide levels in peripheral tissues (1mg/kg, i.p.) and exert antinociceptive action. The CNS-penetrant FAAH Inhibitor II, URB597 is also available. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Serine Hydrolase Inhibitor-4 Quick inquiry Where to buy Suppliers range | Serine Hydrolase Inhibitor-4. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 651293-08-2. Pack Sizes: 5MG. Mole weight: 373.37. Catalog: AP651293082. | |
Serine Hydrolase Inhibitor-5 Quick inquiry Where to buy Suppliers range | Serine Hydrolase Inhibitor-5. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 720664-62-0. Pack Sizes: 5MG. Mole weight: 387.40. Catalog: AP720664620. | |
1-(1-Ethoxyethoxy)-4-fluoronaphthalene Quick inquiry Where to buy Suppliers range | 1-(1-Ethoxyethoxy)-4-fluoronaphthalene is a derivative of 1-Fluoronaphthalene, a fluorinated naphthalene derivative that is metabolized by fungal monooxygenase-epoxide hydrolase. Duloxetine impurity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 1g. Molecular Formula: C14H15FO2, Molecular Weight: 234.27. US Biological Life Sciences. | Worldwide |
1-(2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl)imidazole Quick inquiry Where to buy Suppliers range | 1-(2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl)imidazole, a highly efficient glycosylation reagent, has shown remarkable utility in the synthesis of glycans and glycoconjugates. Its applications have expanded to the development of glycoside hydrolase inhibitors as well as in the preparation of oligosaccharides. The versatility and efficacy of this chemical compound make it a valuable tool in glycosylation research. Synonyms: 1-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)imidazole; 38953-70-7; [(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-imidazol-1-yloxan-2-yl]methyl acetate; DTXSID60855871; 1-(2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl)-1H-imidazole; [(2R,3R,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-(1H-imidazol-1-yl)oxan-2-yl]methyl acetate; (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(1H-imidazol-1-yl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 38953-70-7. Molecular formula: C17H22N2O9. Mole weight: 398.4. | |
1,3-dimethyl-1H-indazol-6-amine Quick inquiry Where to buy Suppliers range | 1,3-dimethyl-1H-indazol-6-amine is an impurity in the synthesis of Pazopanib (P210925) which is an oral angiogenesis inhibitor targeting VEGFR and PDGFR. It is used as a reagent in the preparation of glycinamide derivatives which are useful in production of drugs for preventing and treating diseases caused by S-adenosyl homocysteine hydrolase. Group: Biochemicals. Grades: Highly Purified. CAS No. 221681-92-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C9H11N3, Molecular Weight: 161.199999999999. US Biological Life Sciences. | Worldwide |
1,4-b-D-Cellotetraitol Quick inquiry Where to buy Suppliers range | 1,4-b-D-Cellotetraitol is a saccharide that can acts as a chemical probe for studying Glycoside Hydrolase Enzyme mechanisms, which are involved in research of various diseases including Gaucher's disease and Tay-Sachs disease. CAS No. 5548-55-0. Molecular formula: C24H44O21. Mole weight: 668.59. | |
1,4-b-D-Xylopentaose Quick inquiry Where to buy Suppliers range | 1,4-b-D-Xylopentaose is a hemicellulose-derived pentasaccharide. It's instrumental for studying xylanases and glycoside hydrolases and their role in the degradation of complex carbohydrates within the human digestion system. CAS No. 49694-20-4. Molecular formula: C25H42O21. Mole weight: 678.59. | |
15(S)-HETE ethanolamide Quick inquiry Where to buy Suppliers range | Arachidonoyl ethanolamide (AEA) was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC. 15(S)-HETE ethanolamide is less potent than AEA at the CB1 receptor (Ki of 600 versus 90 nM). 15(S)-HETE ethanolamide also inhibits fatty acid amide hydrolase. Synonyms: 15(S)-hydroxy-N-(2-hydroxyethyl)-5Z,8Z,11Z,13E-eicosatetraenamide; 15(S)-HAEA. Grades: >98%. CAS No. 161744-53-2. Molecular formula: C22H37NO3. Mole weight: 363.5. | |
1,6-Diazaspiro[3.3]heptane-1-carboxylic Acid 1,1-Dimethylethyl Ester Quick inquiry Where to buy Suppliers range | 1,6-Diazaspiro[3.3]heptane-1-carboxylic Acid 1,1-Dimethylethyl Ester is used to prepare azetidine compounds as soluble epoxide hydrolase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1330763-95-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H18N2O2, Molecular Weight: 198.26. US Biological Life Sciences. | Worldwide |
(±)17(18)-EpETE-Ethanolamide Quick inquiry Where to buy Suppliers range | (±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide. It is formed from the endocannabinoid eicosapentaenoic ethanolamide (EPEA) via cytochrome P450 (CYP) epoxygenases and hydrolyzed by soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH). Synonyms: 17,18-EEQ-EA; (±)17,18-EEQ-Ethanolamide; (±)17(18)-EpETE-EA; 17,18-epoxy-Eicosatetraenoic Acid Ethanolamide. Grades: ≥98%. CAS No. 2123491-23-4. Molecular formula: C22H35NO3. Mole weight: 361.5. | |
1-Fluoro-2-iodoethane Quick inquiry Where to buy Suppliers range | 1-Fluoro-2-iodoethane is used as a reagent in organic synthesis of several compounds including that of fluorinated U-50488 analogs for PET studies of kappa opioid receptors. It is also used in the synthesis of MK-3168, an imidazole analog which acts as a PET tracer for the imaging of brain fatty acid amide hydrolase. Group: Biochemicals. Grades: Highly Purified. CAS No. 762-51-6. Pack Sizes: 1g, 5g. Molecular Formula: C2H4FI, Molecular Weight: 173.96. US Biological Life Sciences. | Worldwide |
1-Fluoro-2-naphthaldehyde Quick inquiry Where to buy Suppliers range | 1-Fluoro-2-naphthaldehyde is a synthetic building block that can be synthesized from 1-Fluoronaphthalene (F593760), a fluorinated naphthalene derivative that is metabolized by fungal monooxygenase-epoxide hydrolase. Group: Biochemicals. Grades: Highly Purified. CAS No. 143901-96-6. Pack Sizes: 100mg, 500mg. Molecular Formula: C11H7FO, Molecular Weight: 174.17. US Biological Life Sciences. | Worldwide |
1-Fluoronaphthalene Quick inquiry Where to buy Suppliers range | A fluorinated naphthalene derivative that is metabolized by fungal monooxygenase-epoxide hydrolase. Duloxetine impurity. Group: Biochemicals. Grades: Highly Purified. CAS No. 321-38-0. Pack Sizes: 1g, 10g, 25g. Molecular Formula: C??H?F. US Biological Life Sciences. | Worldwide |
1H-Indole-3-acetamide Quick inquiry Where to buy Suppliers range | Indole-3-acetamide is a compound that is converted to indole-3-acetic acid by indole-3-acetamide hydrolase in auxin biosynthesis in plants. Group: Biochemicals. Grades: Highly Purified. CAS No. 879-37-8. Pack Sizes: 1g, 5g. Molecular Formula: C10H10N2O. US Biological Life Sciences. | Worldwide |
2,2,2-Trichloroethyl Chloroformate Quick inquiry Where to buy Suppliers range | 2,2,2-Trichloroethyl Chloroformate is a general reagent for the demethylation of tertiary methylamines. It is used as a reagent in the synthesis of a series of piperazine ureas as fatty acid amide hydrolase inhibitors and analgesics. Also used as a reagent in the synthesis of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 17341-93-4. Pack Sizes: 1g, 10 g. Molecular Formula: C3H2Cl4O2. US Biological Life Sciences. | Worldwide |
2,4-Dinitrophenyl α-D-Galactopyranoside Quick inquiry Where to buy Suppliers range | 2,4-Dinitrophenyl α-D-Galactopyranoside is used in the synthesis of 2,4-Dinitrophenyl Glycoside and in the glycoside hydrolases anlaysis. CAS No. 25694-52-4. Molecular formula: C12H14N2O10. Mole weight: 346.25. | |
2,4-Dinitrophenyl α-D-Galactopyranoside Quick inquiry Where to buy Suppliers range | 2,4-Dinitrophenyl α-D-Galactopyranoside is used in the synthesis of 2,4-Dinitrophenyl Glycoside. It is also used in the anlaysis of glycoside hydrolases. Group: Biochemicals. Grades: Highly Purified. CAS No. 25694-52-4. Pack Sizes: 10mg, 100mg. Molecular Formula: C12H14N2O10, Molecular Weight: 346.25. US Biological Life Sciences. | Worldwide |
2,6-Dichlorobenzyl Bromide Quick inquiry Where to buy Suppliers range | 2,6-Dichlorobenzyl Bromide is used in the preparation of potent epoxide hydrolase inhibitors. Has shown thus far to relieve hypotension in lipopolysaccharide deficient murine models. As well they have been used in the synthesis of anti-HIV drugs based on diaryltriazine (DATA) analogues. Group: Biochemicals. Alternative Names: 2-(Bromomethyl)-1,3-dichlorobenzene; α-Bromo-2,6-dichloro-toluene; 1-Bromomethyl-2,6-dichlorobenzene; 2,6-Dichloro-α-bromotoluene; 2,6-Dichlorobenzyl Bromide; 2-(Bromomethyl)-1,3-dichlorobenzene; NSC 93898; α-Bromo-2,6-dichlorotoluene. Grades: Highly Purified. CAS No. 20443-98-5. Pack Sizes: 50g. US Biological Life Sciences. | Worldwide |
2-Amino-1-(4-phenoxyphenyl)ethanol Quick inquiry Where to buy Suppliers range | 2-Amino-1-(4-phenoxyphenyl)ethanol is used as a reagent in the synthesis of (4-phenoxyphenyl) tetrazolecarboxamides and its related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). Group: Biochemicals. Grades: Highly Purified. CAS No. 153285-74-6. Pack Sizes: 100mg, 1g. Molecular Formula: C14H15NO2, Molecular Weight: 229.27. US Biological Life Sciences. | Worldwide |
2-Amino-1-[4- (trifluoromethoxy) phenyl]ethanol Quick inquiry Where to buy Suppliers range | 2-Amino-1-[4- (trifluoromethoxy) phenyl]ethanol is used to prepare heteroaryl derivatives such as 4-aminopyrimidine derivatives as fatty acid amide hydrolase (FAAH) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1038262-63-3. Pack Sizes: 100mg, 1g. Molecular Formula: C9H10F3NO2, Molecular Weight: 221.18. US Biological Life Sciences. | Worldwide |
2-Azido-4,6-O-benzylidene-N-Boc-1,2,5-trideoxy-1,5-imino-D-glucitol Quick inquiry Where to buy Suppliers range | 2-Azido-4,6-O-benzylidene-N-Boc-1,2,5-trideoxy-1,5-imino-D-glucitol, a chemical compound commonly employed in the biomedical industry to investigate the inhibitory properties of glycoside hydrolases, exhibits tremendous potential for treating ailments associated with carbohydrate metabolism, such as diabetes and obesity. Its integration in the pharmaceutical field has garnered significance, with researchers observing its dynamic properties and investigating how its unique molecular structure impacts the inhibition of glycoside hydrolases. Molecular formula: C14H24N4O5. Mole weight: 328.36. | |
2-Carboxyethylboronic Acid, Pinacol Ester Quick inquiry Where to buy Suppliers range | 2-Carboxyethylboronic Acid, pinacol ester acts as a reagent in the preparation of oxadiazolylphenyl Boronic acid derivatives and analogs for use as fatty acid amide hydrolase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1191063-90-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H17BO4, Molecular Weight: 200.04. US Biological Life Sciences. | Worldwide |
2-Cyanomethylthioadenosine Quick inquiry Where to buy Suppliers range | 2-Cyanomethylthioadenosine, a powerful inhibitor of S-adenosylhomocysteine hydrolase (SAHH), the regulator of methylation pressure and a participant in the development of cancer, is a highly effective modulator of extracellular metabolism, opening doors for therapeutic interventions in cancer, inflammation, and immunomodulation, illuminating its status as a multifaceted agent at the cutting-edge of biochemistry. Grades: ≥95%. CAS No. 2095417-67-5. Molecular formula: C12H14N6O4S. Mole weight: 338.34. | |
(2E)-3-(4-Phenoxyphenyl)-2-propenoic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | (2E)-3-(4-Phenoxyphenyl)-2-propenoic Acid Ethyl Ester is used as a reagent to evaluate structure-activity relationships of ketooxazole inhibitors of fatty acid amide hydrolase. Group: Biochemicals. Grades: Highly Purified. CAS No. 945414-28-8. Pack Sizes: 1g, 10g. Molecular Formula: C17H16O3, Molecular Weight: 268.31. US Biological Life Sciences. | Worldwide |
2-Nitrophenyl a-D-glucopyranoside Quick inquiry Where to buy Suppliers range | 2-Nitrophenyl α-D-glucopyranoside is a highly esteemed compound, serving as an impeccable tool for the meticulous investigation of enchanting enzymatic activities and the momentous impact of potent inhibitors. Its illustrious presence in the realm of scientific research is indubitably intertwined with the elucidation of the captivating complexities surrounding glycosidases and glycoside hydrolases. Boasting an incomparable reactivity as a substrate, this extraordinary compound facilitates the striking detection and meticulous quantification of these celestial enzymes. Synonyms: 2-Nitrophenyl a-D-glucopyranoside; 56193-44-3; SCHEMBL150631; r-nitrophenyl alpha-d-glucopyranoside; AKOS015919352; HY-148672; CS-0636848. CAS No. 56193-44-3. Molecular formula: C12H15NO8. Mole weight: 301.25. | |
2-Nitrophenyl b-D-cellobioside Quick inquiry Where to buy Suppliers range | 2-Nitrophenyl b-D-cellobioside, a chemical compound utilized in the realm of enzymology and biochemistry, finds its purpose in the detection of different types of enzymes, especially glycoside hydrolases. Its functionalities are not limited to this, however, as it can also be employed to analyze carbohydrate-binding proteins. Widely renowned for its ability to influence the development of biosensors for detecting environmental contaminants, this product stands to revolutionize the approach to the pesticide problem that currently plagues our society. Synonyms: 2-Nitrophenyl β-D-cellobioside; ONP-cellobioside; o-Nitrophenyl β-D-Cellobioside; 2-Nitrophenyl 4-O-β-D-Glucopyranosyl-β-D-glucopyranoside. Grades: ≥95%. CAS No. 70867-33-3. Molecular formula: C18H25NO13. Mole weight: 463.39. | |
2-(Nonylthio)propanamide Quick inquiry Where to buy Suppliers range | 2-(Nonylthio)propanamide is an potential selective inhibitor of epoxide hydrolase virulence factor from pseudomonas aeruginosa which contributes to cystic fibrosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1021343-21-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C12H25NOS. US Biological Life Sciences. | Worldwide |
2'-O-(N-Methylanthraniloyl)-3'-deoxy-adenosine-5'-triphosphate triethylammonium salt Quick inquiry Where to buy Suppliers range | 2'-O-(N-Methylanthraniloyl)-3'-deoxy-adenosine-5'-triphosphate triethylammonium salt, a highly significant compound in biomedical studies, serves as the triethylammonium salt version of 2'-O-(N-Methylanthraniloyl)-3'-deoxy-adenosine-5'-triphosphate. This invaluable substance finds noteworthy applications in the exploration of ATP-dependent cellular mechanisms and signaling cascades within the realm of biomedical research. Notably, it assumes a pivotal role in the examination of ATP-binding proteins, including receptors, kinases, and nucleotide hydrolases, thereby contributing to the emergence of innovative therapeutic strategies for diverse pathological conditions and ailments. Synonyms: 2'-Mant-3'-dATP. Molecular formula: C18H23N6O13P3·xC6H15N. Mole weight: 624.33 (free acid). | |
(2S) ?-2-?[[4-? (4-Chlorophenoxy) ?phenoxy]?methyl]?-1-?pyrrolidinebutanoic Acid Hydrochloride Quick inquiry Where to buy Suppliers range | (2S) ?-2-?[[4-? (4-Chlorophenoxy) ?phenoxy]?methyl]?-1-?pyrrolidinebutanoic Acid Hydrochloride is a potent inhibitor leukotriene A4 hydrolase (LTA4H), which is a therapeutic target for developing treatments for cardiovascular diseases and cancers. Group: Biochemicals. Grades: Highly Purified. CAS No. 929915-58-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C21H25Cl2NO4, Molecular Weight: 426.33. US Biological Life Sciences. | Worldwide |
2- (Tributylstannyl) oxazole Quick inquiry Where to buy Suppliers range | 2- (Tributylstannyl) oxazole is a useful reactant in preparation of potent, selective and efficacious reversible α-ketoheterocycle inhibitors of fatty acid amide hydrolase effective as analgesics. Group: Biochemicals. Grades: Highly Purified. CAS No. 145214-05-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C15H29NOSn, Molecular Weight: 358.11. US Biological Life Sciences. | Worldwide |
3,5-Dinitrosalicylic acid 99+% (HPLC) Quick inquiry Where to buy Suppliers range | 3,5-Dinitrosalicylic acid (DNS) is used in colorimetric determination of reducing sugars and to analyze glycosidase (glycoside hydrolase) activity by quantitation of enzymatically released reducing sugar. The dinitrosalicylic acid method has been compared to the Nelson-Somogi colorimetric method. 3,5-Dinitrosalicylic acid (DNS) has been used to stop the reaction in in vitro α-amylase inhibition study. It has also been used for the quantitation of enzymatically released reducing sugars. Group: Biochemicals. Alternative Names: 2-Hydroxy-3,5-dinitro-benzoic Acid; 2-Hydroxy-3,5-dinitrobenzoic Acid; 3,5-Dinitro-2-hydroxybenzoic Acid; NSC 181. Grades: Highly Purified. CAS No. 609-99-4. Pack Sizes: 25g, 100g, 250g, 1Kg. Molecular Formula: C7H4N2O7. US Biological Life Sciences. | Worldwide |
3-Cyanobenzeneboronic acid Quick inquiry Where to buy Suppliers range | 3-Cyanophenylboronic acid is a novel fatty acid amide hydrolase inhibitor. Synonyms: B-(3-Cyanophenyl)boronic Acid; (m-Cyanophenyl)boronic Acid; 3-Cyanobenzeneboronic Acid; 3-Cyanophenylboronic Acid; 3-Boronobenzonitrile; Boronic acid, B-(3-cyanophenyl)-; 3-(dihydroxyboranyl)benzonitrile; ACMC-1C8U1; 3-Cyano Phenyl Boronic Acid. Grades: > 98 % (HPLC). CAS No. 150255-96-2. Molecular formula: C7H6BNO2. Mole weight: 146.94. | |
3-Deazaadenosine Quick inquiry Where to buy Suppliers range | 3-Deazaadenosine (3-DZA) is an inhibitor of SAH hydrolase (Ki = 3.9 μM). Synonyms: Deaza-Ado; (2R,3R,4S,5R)-2-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 3-Deaza-rA; 1-(beta-D-ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine; 4-Amino-1-(β-D-ribofuranosyl)-1H-imidazo(4,5)-pyridine. Grades: ≥97% by HPLC. CAS No. 6736-58-9. Molecular formula: C11H14N4O4. Mole weight: 266.26. | |
3-Deazaadenosine hydrochloride Quick inquiry Where to buy Suppliers range | It is an S-adenosine homocysteine hydrolase inhibitor. It has anti-inflammatory effects, inhibiting leukocyte adhesion and chemotaxis, lymphocyt-mediated cytolysis, phagocytosis, degranulation and NF-κB signal transduction. Synonyms: 3-Deaza-Adenosine hydrochloride; 3-Deaza-rA Hcl; 1-(β-D-Ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine hydrochloride (1:1); 1H-Imidazo[4,5-c]pyridin-4-amine, 1-β-D-ribofuranosyl-, hydrochloride (1:1). Grades: ≥97% by HPLC. CAS No. 86583-19-9. Molecular formula: C11H15ClN4O4. Mole weight: 302.71. | |
3-Deazaneplanocin A Quick inquiry Where to buy Suppliers range | 3-Deazaneplanocin A is a a powerful inhibitor of S-adenosylhomocysteine hydrolase that has shown potent and selective in vitro and in vivo antiviral activities. Group: Biochemicals. Alternative Names: (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol Hydrochloride;[1S-(1α,2α,5 β)]-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol Monohydrochloride. Grades: Highly Purified. CAS No. 120964-45-6. Pack Sizes: 500ug, 1mg, 5mg. Molecular Formula: C??H??ClN?O?, Melting Point: >185°C (dec.). US Biological Life Sciences. | Worldwide |
3-deazaneplanocin A (DZNeP) HCl Quick inquiry Where to buy Suppliers range | 3-deazaneplanocin A (DZNeP)HCl, an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM. Synonyms: NSC 617989 HCl; NSC617989 HCl; NSC-617989 HCl; 3-deazaneplanocin A HCl; 3-deazaneplanocin A hydrochloride; DZNep. Grades: >98%. CAS No. 120964-45-6. Molecular formula: C12H15ClN4O3. Mole weight: 298.72. | |
3-Hydroxyisobutyryl CoA Quick inquiry Where to buy Suppliers range | 3-Hydroxyisobutyryl CoA is an intermediate in the valine catabolic pathway in eukaryotes. Synonyms: 3-Hydroxyisobutyryl Coenzyme A Hydrolase; 3-Hydroxyisobutyryl CoA Hydrolase; 3-Hydroxyisobutyryl Coenzyme A; 3-Hydroxyisobutyryl Coenzyme A Hydrolase; E.C. 3.1.2.4; EC 3.1.2.4; β-Hydroxyisobutyryl-CoA Hydrolase; β-Hydroxyisobutyryl-coenzyme A Hydrolase. CAS No. 9025-88-1. Molecular formula: C25H42N7O18P3S. Mole weight: 853.62. | |
3- (Trifluoromethyl) phenyl Chloroformate Quick inquiry Where to buy Suppliers range | 3- (Trifluoromethyl) phenyl Chloroformate is a reagent in the preparation of tetrahydro- β-carboline derivatives which targets fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channels. Group: Biochemicals. Grades: Highly Purified. CAS No. 95668-29-4. Pack Sizes: 250mg, 500mg. Molecular Formula: C8H4ClF3O2, Molecular Weight: 224.56. US Biological Life Sciences. | Worldwide |
4,5,6,7-Tetrachloro-1H-indene-1,3(2H)-dione (TCID) Quick inquiry Where to buy Suppliers range | Cell-permeable. A potent and selective inhibitor of ubiquitin C-terminal hydrolase L3 (UCH-L3) (IC50=0.6uM). Inhibits ubiquitin C-terminal hydrolase L1 (UCH-L1) only at higher concentrations (IC50 = 75uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
4-Acetylbutyric Acid-d5 Quick inquiry Where to buy Suppliers range | Product formed by Cyclohexan-1,3-dione Hydrolase enzyme. Group: Biochemicals. Alternative Names: 5-Oxo-hexanoic Acid-d5; 5-Ketocaproic Acid-d5; 5-Ketohexanoic Acid-d5; 5-Oxocaproic Acid-d5; 5-Oxohexanoic Acid-d5; NSC 5281-d5. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
4-Methylphenyl b-D-galactopyranoside Quick inquiry Where to buy Suppliers range | 4-Methylphenyl b-D-galactopyranoside is a valuable compound exhibiting potential as a substrate for various enzymatic assays and commonly employed in the biochemical analysis of glycoside hydrolases. This compound plays a crucial role in understanding and discovering novel therapeutic drugs, particularly in research related to carbohydrate metabolism and galactoside-specific enzymes. Synonyms: p-Tolyl-b-D-galactopyranoside. CAS No. 3150-22-9. Molecular formula: C13H18O6. Mole weight: 270.28. | |
4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside Quick inquiry Where to buy Suppliers range | 4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is a fluorogenic substrate for palmitoyl-protein thioesterase (PPT), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. It is cleaved by PPT to produce fluorescent moiety 4-MU. It can be used in the diagnosis of infantile neuronal ceroid lipofuscinosis (INCL). Synonyms: Mu-6S-Palm-β-Glc; 4-methyl-7-[[6-S-(1-oxohexadecyl)-6-thio-β-D-glucopyranosyl]oxy]-2H-1-benzopyran-2-one. Grades: ≥95%. CAS No. 229644-17-1. Molecular formula: C32H48O8S. Mole weight: 592.8. | |
4-Nitrophenyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-a-D-glucopyranoside Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-a-D-glucopyranoside, an indispensable compound in the realm of biomedicine, boasts a multitude of uses. Embraced widely in glycosylation research, it unravels the intricate tapestry of carbohydrates' biological phenomena. Employed as a substrate for enzyme assays, this compound delves into the realm of glycoside hydrolases, sugar transporters, and carbohydrate metabolism. Synonyms: Gal-b-1,4-GlcNAc-a-PNP PNP-N-Acetyl-a-D-lactosamine PNP-a-LacNAc. CAS No. 184377-56-8. Molecular formula: C20H28N2O13. Mole weight: 504.44. | |
4-Nitrophenyl 2-O-(a-D-glucopyranosyl)-a-D-glucopyranoside Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl 2-O-(a-D-glucopyranosyl)-a-D-glucopyranoside is a highly intricate biomedical compound, acting as an effectively stifling glycoside hydrolase that governs carbohydrate metabolism. This potent enzyme inhibitor has applicantion in research of ameliorating aberrant glucose processing. Synonyms: 4-Nitrophenyl a-kojibioside PNP-a-kojibioside. CAS No. 147103-31-9. Molecular formula: C18H25NO13. Mole weight: 463.39. | |
4-Nitrophenyl a-L-arabinofuranoside Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl α-L-arabinofuranoside, a remarkable biomedical product, emerges as a paramount asset for addressing specific afflictions. Serving as a substrate mimetic within enzymatic analyses and scientific investigations, this chemical compound unveils its potential. Its intricate configuration facilitates the in-depth scrutiny of diverse glycoside hydrolases and glycosyltransferases intricately entwined in carbohydrate metabolism. With its implications in drug discovery and precision medicine, this compound incessantly enlightens us about the pivotal role these enzymes play in maintaining sound health and combating diseases. Synonyms: 4-Nitrophenyl a-L-arabinofuranoside; 4-NITROPHENYL-ARA; 4-Nitrophenyl-alpha-L-arabinofuranoside; 4-nitrophenyl alpha-L-arabinofuranoside; 4-Nitrophenyl |A-L-arabinofuranoside; pNP-alpha-L-Arabinofuranoside; (2S,3R,4R,5S)-2-(hydroxymethyl)-5-(4-nitrophenoxy)oxolane-3,4-diol; p-Nitrophenyl alpha-L-arabinofuranoside; alpha-L-Arabinofuranoside, 4-nitrophenyl; (2S,3R,4R,5S)-2-(hydroxymethyl)-5-(4-nitrophenoxy)tetrahydrofuran-3,4-diol; pNPalphaAraf; 4-Nitrophenyla-L-arabinofuranoside; p-Nitrophenylalpha-L-arabinofuranoside. CAS No. 6892-58-6. Molecular formula: C11H13NO7. Mole weight: 271.22. | |
4-Nitrophenyl b-L-arabinopyranoside Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl b-L-arabinopyranoside is a valuable substrate for biomedical applications, specifically in the measurement of glycoside hydrolase activity, such as β-D-arabinofuranosidase, in drug discovery and enzymatic studies. Additionally, it is utilized in the study of L-arabinose and xylose metabolism in bacteria and fungi, and elucidates their relevance to pathways implicated in diseases including diabetes. Through utilization of this specialized substrate, significant advances can be made in the fields of biomedicine and microbiology research. Synonyms: PNP-arabinoside; (2R,3R,4S,5S)-2-(4-Nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triol; P-nitrophenyl β-L-arabinopyranoside. Grades: ≥95%. CAS No. 72732-54-8. Molecular formula: C11H13NO7. Mole weight: 271.22. | |
4-Nitrophenyl O-(N-acetyl-a-neuraminosyl)-(2-3)-b-D-galactopyranosyl-(1-4)-2-acetamido-2-deoxy-b-D-glucopyranoside Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl O-(N-acetyl-α-neuraminosyl)-(2-3)-β-D-galactopyranosyl-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranoside, a compound of interest in biomedical research, presents a fascinating opportunity to explore cell recognition and immune response mechanisms. Leveraging its properties, scientists can delve into the involvement of glycosidases in lysosomal storage diseases and analyze the enzymatic activity of glycoside hydrolases. Notably, this compound holds promise in developing therapeutics that can effectively combat drug-resistant bacterial infections. Synonyms: Neu5Aca(2-3)Galb(1-4)GlcNAc-b-pNP. CAS No. 501427-92-5. Molecular formula: C31H45N3O21. Mole weight: 795.70. | |
4-(n-nonyl) benzeneboronic acid Quick inquiry Where to buy Suppliers range | Fatty acid amide hydrolase (FAAH) is the primary enzyme responsible for the hydrolysis of the endocannabinoid arachidonoyl ethanolamide (AEA). 4-(n-nonyl) benzeneboronic acid is a potent inhibitor of FAAH, with an IC50 of 9.1 nM. Synonyms: 4-Nonylphenylboronic acid; (4-nonylphenyl)boronic acid. Grades: ≥98%. CAS No. 256383-45-6. Molecular formula: C15H25BO2. Mole weight: 248.2. | |
4-O-(a-D-Glucopyranosyl) moranoline Quick inquiry Where to buy Suppliers range | 4-O-(α-D-Glucopyranosyl) moranoline, a compound of significant value in the biomedical realm, possesses potential advantages for addressing certain medical conditions. Within drug development, it specifically targets enzymes associated with diverse metabolic processes, offering therapeutic prospects encompassing diabetes, cancer, and cardiovascular ailments. Uses: Glycoside hydrolase inhibitors. Synonyms: G1M 4-O-(a-D-Glucopyranosyl)-1-deoxynojirimycin. CAS No. 80312-32-9. Molecular formula: C12H23NO9. Mole weight: 325.32. | |
4-Phenylchalcone oxide Quick inquiry Where to buy Suppliers range | 4-Phenylchalcone oxide, 82389-34-2, CCRIS 2240, phenyl-[3-(4-phenylphenyl)oxiran-2-yl]methanone, SCHEMBL655373, BDBM6120, CHEMBL3661417, DTXSID901002648, LS-188793, US8815951, Epoxide Hydrolase Inhibitor 8, SR-01000597661, SR-01000597661-1, [3-([1,1'-Biphenyl]-4-yl)oxiran-2-yl](phenyl)methanone. | |
(±)5(6)-DiHET Quick inquiry Where to buy Suppliers range | Epoxide hydrolases convert the EETs into vicinal diols, with concurrent loss of much of their biological activity. (±)5(6)-DiHET is a substrate for sheep seminal vesicle COX, producing 5,6-dihydroxy prostaglandin E1 and F1α metabolites in vitro. Synonyms: (±)5,6-DiHETrE; 5,6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid; (8Z,11Z,14Z)-5,6-Dihydroxyicosa-8,11,14-trienoic acid. Grades: ≥95%. CAS No. 213382-49-1. Molecular formula: C20H34O4. Mole weight: 338.5. | |
(±)5(6)-EET Ethanolamide Quick inquiry Where to buy Suppliers range | Arachidonyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic activity. It binds to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of AEA. Synonyms: (±)5,6-EpETrE Ethanolamide; N-(2-hydroxyethyl)-4-[(2S,3R)-3-[(2Z,5Z,8Z)-tetradeca-2,5,8-trienyl]oxiran-2-yl]butanamide. Grades: ≥95%. Molecular formula: C22H37NO3. Mole weight: 363.5. | |
5-Bromo-6-chloro-3-indolyl butyrate Quick inquiry Where to buy Suppliers range | 5-Bromo-6-chloro-3-indolyl butyrate is a widely employed compound in the biomedical sector, serving as a pivotal substrate for the identification of diverse enzymes encompassing esterases and hydrolases. Its multifarious applications in drug discovery and biochemical research are attributed to its significance in comprehending the intricate mechanisms underlying pathophysiological conditions such as cancer, inflammation and neurological disturbances. Molecular formula: C12H11BrClNO2. Mole weight: 316.58. | |
5(S),6(R)-DiHETE Quick inquiry Where to buy Suppliers range | 5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4). Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA4 to 5(S),6(R)-DiHETE. 5(S),6(R)-DiHETE is a weak LTD4 receptor agonist in guinea pig lung membranes. It induces guinea pig ileum contraction with an ED50 value of 1.3 μM. Synonyms: (5S,6R,7E,9E,11Z,14Z)-5,6-dihydroxyicosa-7,9,11,14-tetraenoic acid. Grades: ≥95%. CAS No. 82948-88-7. Molecular formula: C20H32O4. Mole weight: 336.5. | |
8-Bromo-GTP Quick inquiry Where to buy Suppliers range | 8-Bromo-GTP is a GTP analog that can inhibit GTP-hydrolase. It competitively inhibits GTPase (IC50 = 32 μM) and competes with ATP for the binding center of RNA-polymerase. Synonyms: (8Br-GTP); 8-Bromo-guanosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 23197-98-0. Molecular formula: C10H15N5O14P3Br (free acid). Mole weight: 602.07 (free acid). | |
8-Fluoroadenosine Quick inquiry Where to buy Suppliers range | 8-Fluoroadenosine is an extraordinary compound, acting as a highly selective inhibitor of S-adenosylhomocysteine hydrolase (SAHH) within the dynamic realm of cellular biochemistry. Synonyms: 8-fluoro-adenosine; (2R,3R,4S,5R)-2-(6-Amino-8-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 23205-67-6. Molecular formula: C10H12FN5O4. Mole weight: 285.23. | |
AA26-9 Quick inquiry Where to buy Suppliers range | AA26-9, synthesized based on a piperazine scaffold, is a potent and broad spectrum serine hydrolase inhibitor. Synonyms: AA 26-9; AA-26-9; AA26-9; AA 269; AA-269; AA269; pyrrolidin-1-yl(triazol-1-yl)methanone; Pyrrolidin-1-yl(1H-1,2,3-triazol-1-yl)methanone. CAS No. 1312782-34-5. Molecular formula: C7H10N4O. Mole weight: 166.18. | |
AACOCF Quick inquiry Where to buy Suppliers range | AACOCF, an anlogue of arachidonic acid, is a slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2. It also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. Synonyms: 1,1,1-Trifluoro-6Z,9Z,12Z,15Z-heneicosateraen-2-one; Arachidonyl trifluoromethyl ketone; Arachidonyltrifluoromethane. CAS No. 149301-79-1. Molecular formula: C21H31F3O. Mole weight: 356.47. | |
Ac-Nle-Pro-Nle-Asp-AMC Quick inquiry Where to buy Suppliers range | Ac-Nle-Pro-Nle-Asp-AMC is a substrate for proteasomes. It can be cleaved by the caspase-like site of proteasome, also known as postglutamyl peptide hydrolase (PGPH). AMC (7-amino-4-methylcoumarin) is released and produces the fluorescence utilized to quantify the caspase-like site activity. Ac-Nle-Pro-Nle-Asp-AMC also inhibits the chymotrypsin-like activity of the proteasome allosterically when bound to the caspase-like site. Synonyms: Ac-Nle-Pro-Nle-Asp-7-amido-4-Methylcoumarin; Ac-nLPnLD-AMC; N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine; L-α-Asparagine, N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; (3S) -4-Hydroxy-3- ({ (2S) -1-hydroxy-2-[ (hydroxy{ (2S) -1-[N- (1-hydroxyethylidene) -L-norleucyl]-2-pyrrolidinyl}methylene) amino]hexylidene}amino) -4-[ (4-methyl-2-oxo-2H-chromen-7-yl) imino]butanoic acid. Grades: ≥98%. CAS No. 355140-49-7. Molecular formula: C33H45N5O9. Mole weight: 655.74. | |
Adenosine dialdehyde Quick inquiry Where to buy Suppliers range | Adenosine dialdehyde is an irreversible inhibitor of S-adenosylhomocysteine hydrolase (IC50 = 40 nM), blocking the conversion of SAH to homocysteine and adenosine. Synonyms: 2-[1-(6-aminopurin-9-yl)-2-oxoethoxy]-3-hydroxypropanal. Grades: ≥ 95 %. CAS No. 34240-05-6. Molecular formula: C10H11N5O4. Mole weight: 265.23. | |
AM3102 Quick inquiry Where to buy Suppliers range | AM-3102 is an Oleoyl ethanolamide (OEA) analog that stimulates PPARα transcriptional activity with an EC50 value of 100 nM and prolongs feeding latency. The biological effects of OEA are terminated by N-acylethanolamine-hydrolyzing acid amidase and fatty-acid amide hydrolase. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 33 and 26 μM, respectively. Synonyms: KDS-5104; AM-3102; AM 3102; Methyl oleoylethanolamide. Grades: ≥98%. CAS No. 213182-22-0. Molecular formula: C21H41NO2. Mole weight: 339.6. | |
AM404 Quick inquiry Where to buy Suppliers range | AM-404 is a selective inhibitor of the carrier-mediated transport of anandamide without affecting anandamide hydrolysis. AEM is also an analog of arachidonyl ethanolamide (AEA) which potentiates the activity of endogenous AEA by blocking its reuptake into presynaptic neurons. AM404 inhibits endocannabinoid cellular uptake, binds weakly to CB1 and CB2 cannabinoid receptors, and is formed by fatty acid amide hydrolase (FAAH) in vivo. Synonyms: 5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (5Z,8Z,11Z,14Z)-; (5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenamide; 5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (all-Z)-; AM 404; AM404. Grades: ≥98%. CAS No. 183718-77-6. Molecular formula: C26H37NO2. Mole weight: 395.58. | |
Arachidonyl serotonin Quick inquiry Where to buy Suppliers range | Arachidonyl serotonin is a dual target agent of transient receptor potential vanilloid-type I (TRPV1) antagonist and fatty acid amide hydrolase (FAAH) inhibitor, which is responsible for inactivation of anandamide and other endogenous cannabinoids. Its IC50 values are 37-40 nM and 5.6 μM for TRPV1 and FAAH respectively. It inhibits the FAAH activity isolated from mouse neuroblastoma cells with an IC50 value of 12 μM. It is a very tight binding, competitive inhibitor of FAAH. It does not inhibit cPLA2 and is essentially devoid of cannabimimetic activity. It was shown to be present in the ileum and jejunum of the gastrointestinal tract and modulate glucagon-like peptide-1 (GLP-1) secretion. It displays strong analgesic activity against both acute and chronic peripheral pain in rodents. Synonyms: AA-5HT; AA5HT; AA 5HT; N-arachidonoyl-serotonin; Arachidonoyl serotonin; N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide; AA-5HT; AA5HT; N-arachidonoyl-serotonin; N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-eicosatetraenamide; (5Z,8Z,11Z,14Z)-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)icosa-5,8,11,14-tetraenamide. CAS No. 187947-37-1. Molecular formula: C30H42N2O2. Mole weight: 462.67. | |
ARM1 hydrobromide Quick inquiry Where to buy Suppliers range | ARM1 hydrobromide is a novel Leukotriene A4 hydrolase/aminopeptidase (LTA4H) inhibitor (IC50 value of ~0.5 μM in human neutrophils, and Ki value of 2.3 μM for purified LTA4H) that blocks the conversion of LTA4 into proinflammatory mediator LTB4, although leaving the aminopeptidase activity intact for cleavage and inactivation of Pro-Gly-Pro. Synonyms: ARM1 hydrobromide; ARM 1 hydrobromide; ARM-1 hydrobromide; 4-(4-benzylphenyl)-1,3-thiazol-2-amine hydrobromide. Grades: 99%. CAS No. 1049743-03-4. Molecular formula: C16H14N2S.HBr. Mole weight: 347.27. | |
ARN726 Quick inquiry Where to buy Suppliers range | ARN726 is a systemically active and orally bioavailable N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 value of 27 nM for human and 63 nM for rat NAAA. The selectivity for NAAA is better than fatty acid amide hydrolase (FAAH) with IC50s of 100 uM. It is also selective over acid cermidase with IC5Os of 12.5 uM. ARN726 can decrease lung myeloperoxidase activity and pleural exudate TNF-α levels in a mouse model of carrageenan-induced lung inflammation. Synonyms: ARN-0726; ARN 0726. Grades: ≥95%. CAS No. 1628343-77-0. Molecular formula: C14H24N2O3. Mole weight: 268.35. | |
AUDA Quick inquiry Where to buy Suppliers range | AUDA is an inhibitor of soluble epoxide hydrolase with IC50 of 18 nM in mice. AUDA has been shown to demonstrate hypotensive effects, accompanied by an increase in urinary epoxide-to-diol ratios. AUDA can activate peroxisome proliferator-activated receptor α (PPARα) 3-fold, while showing no ability to affect PPARδ or PPAR&gamma. AUDA decreases bleomycin-induced pulmonary toxicity in mice by inhibiting the p38/Smad3 pathways. Synonyms: 12-(3-Adamantan-1-yl-ureido)dodecanoic Acid; 12-[[(Tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]dodecanoic Acid; A 003564556. Grades: >98%. CAS No. 479413-70-2. Molecular formula: C23H40N2O3. Mole weight: 392.6. | |
AUNP-12 Quick inquiry Where to buy Suppliers range | AUNP-12 is highly effective in antagonizing PD-1 signaling, with desirable in vivo exposure upon subcutaneous dosing. It inhibits tumor growth and metastasis in preclinical models of cancer and is well tolerated with no overt toxicity at any of the tested doses. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EpETrEs to the corresponding dihydroxy eicosatrienoic acids (DiHETrEs) thereby diminishing their activity. AUDA is an inhibitor of sEH exhibiting IC50 of 18 nM for the mouse and IC50 of 69 nM forand human enzymes. Synonyms: Aur-012; Aurigene-012; Aurigene NP-12. Grades: ≥95%. CAS No. 1353563-85-5. Molecular formula: C142H226N40O48. Mole weight: 3261.55. | |
Bafilomycin C1 (L-681,110A1, 2-Demethyl-2-methoxy-24-methyl-hygrolidin) Quick inquiry Where to buy Suppliers range | Antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antibacterial, antifungal, insecticidal and antihelmintic. Potential anti-osteoporotic agent in treating bone lytic diseases. Neuroprotection inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 88979-61-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |