Hydroxy Iso Quinoline Suppliers USA
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Product | Description | |
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10-O-Acetyl SN-38-d3 Quick inquiry Where to buy Suppliers range | 10-O-Acetyl SN-38-d3 is the isotope labelled protected metabolite of Irinotecan (I767500), an DNA topoisomerase inhibitor. Group: Biochemicals. Alternative Names: 10-Acetyloxy-7-ethylcamptothecin-d3; (4S)-9-(Acetyloxy)-4, 11-diethyl-4-hydroxy-1H-pyrano[3', 4':6, 7]indolizino[1, 2-b]quinoline-3, 14(4H, 12H)-dione-d3; 10-Hydroxy-7-ethylcamptothecin 10-Acetate-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
AMPK Signaling Agonist, F17 (4-hydroxy-1-isobutyl-N-(5-methylthiazol-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide) Quick inquiry Where to buy Suppliers range | A cell-permeable 4-hydroxy-2-oxo quinoline carboxamide that acts as an agonist of AMPK signaling. It is shown to reduce fat storage in C. elegans (EC50 ~0.1uM) and reduce the expression level of fat-7 (a C. elegans ortholog of mammalian stearoyl-CoA desaturase-1), through aak-1 (an ortholog for the AMPK-a1 catalytic subunit) and K08F8.2 (a transcription factor) dependent mechanisms. In addition, it markedly reduces the number of lipid droplets in HepG2 human hepatocarcinoma cells at 25uM, and elicits the phosphorylation and inactivation of acetyl coenzyme A carboxylase (ACC, the enzyme that catalyzes the rate-limiting step in de novo fatty acid synthesis). F17-induced ACC phosphorylation can be abrogated by simultaneous treatment with an AMPK inhibitor compound C. Group: Biochemicals. Grades: Highly Purified. CAS No. 280112-24-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Apomorphine Sulfate-[d5] Quick inquiry Where to buy Suppliers range | Apomorphine Sulfate-[d5] is an isotope compound of Apomorphine Sulfate, a derivative of Apomorphine. Synonyms: (R)-11-hydroxy-1,2,3,6,8,9-D5-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl hydrogen sulfate; [(9R)-3-hydroxy-10-methyl(5, 6, 14, 15, 16-D5)-10-azatetracyclo[7.7.1.0, 7.0, 7]heptadeca-1(17), 2, 4, 6, 13, 15-hexaen-4-yl]oxidanesulfonic acid. Grades: > 98%. Molecular formula: C17H17NO5S. Mole weight: 352.42. | |
Belotecan Quick inquiry Where to buy Suppliers range | Belotecan binds to and inhibits the activity of topoisomerase I, stabilizing the cleavable complex of topoisomerase I-DNA, which inhibits the religation of single-stranded DNA breaks generated by topoisomerase I. Uses: Topoisomerase i inhibitors. Synonyms: Camtobell; CKD602; CKD 602; CKD-602; (4S)-4-Ethyl-4-hydroxy-11-(2-(isopropylamino)ethyl)-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione. CAS No. 256411-32-2. Molecular formula: C25H27N3O4. Mole weight: 433.50. | |
Camptothecin sodium Quick inquiry Where to buy Suppliers range | An alkaloid topoisomerase I (topo I) inhibitor with anticancer properties. It is isolated from camptotheca acuminata, a deciduous tree or nothapodytes foetida. Synonyms: 20(S)-Camptothecin Sodium Salt; Camptothecine Sodium; NSC 100880; Sodium Camptothecin; (αS)-α-ethyl-9,11-Dihydro-α-hydroxy-8-(hydroxymethyl)-9-oxo-indolizino[1,2-b]quinoline-7-acetic Acid Monosodium Salt; 21,22-Secocamptothecin-21-oic Acid Monosodium Salt. Grades: ≥95%. CAS No. 25387-67-1. Molecular formula: C20H17N2NaO5. Mole weight: 388.35. | |
cis-Montelukast Quick inquiry Where to buy Suppliers range | The cis geometric isomer of Montelukast. An impurity of Montelukast. Group: Biochemicals. Alternative Names: 1- [ [ [ (1R) -1- [3- [ (1Z) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic Acid. Grades: Highly Purified. CAS No. 774538-96-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Decoquinate D5 Quick inquiry Where to buy Suppliers range | Decoquinate D5. Uses: For analytical and research use. Group: Pharma & Vet Compounds & Metabolites; Stable Isotope Labelled Compounds; Pharma & Vet Compounds & Metabolites; Stable Isotope Labelled Compounds. Alternative Names: Decoquinate D5, Ethyl 6-decoxy-4-hydroxy-7-(1,1,2,2,2-pentadeuterioethoxy)quinoline-3-carboxylate,Decoquinate D5 (7-ethoxy D5). CAS No. 1453100-61-2. IUPAC Name: ethyl 6-decoxy-4-hydroxy-7-(1,1,2,2,2-pentadeuterioethoxy)quinoline-3-carboxylate. Molecular formula: C242H5H30NO5. Mole weight: 422.57. Catalog: APS1453100612. SMILES: [2H]C ([2H]) ([2H])C ([2H]) ([2H])Oc1cc2ncc (C (=O)OCC)c (O)c2cc1OCCCCCCCCCC. Format: Neat. Product Type: Stable Isotope Labelled. Shipping: Room Temperature. | |
Procaterol HCl Quick inquiry Where to buy Suppliers range | Procaterol hydrochloride is a long-acting, very potent and specific beta-2-adrenergic receptor agonist. It acts as a vasodialator for long term treatment of asthma. It was developed by Pfizer. Uses: Procaterol hydrochloride acts as a vasodialator for long term treatment of asthma. Synonyms: 5-(1-Hydroxy-2-isopropylamino)butyl-8-hydroxycarbostyril hydrochloride;8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1h)-quinolinonmono;(R*,S*)-(±)-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]quinolin-2(1H)-one monohydrochloride;CI-888;CI888. Grades: 95%. CAS No. 62929-91-3. Molecular formula: C16H23ClN2O3. Mole weight: 326.82. | |
Pyridazinediones-derivative-1 Quick inquiry Where to buy Suppliers range | It inhibits glutamate-induced contractions of isolated guineapig ileum (ED50= 2.1 μM) with potential to treat neurodegenerative disorders. Synonyms: Pyridazino[4,5-b]quinoline-1,4-dione, 7-chloro-2,3-dihydro-10-hydroxy-; 7-chloro-3,5-dihydro-2H-pyridazino[4,5-b]quinoline-1,4,10-trione. CAS No. 147493-44-5. Molecular formula: C11H6ClN3O3. Mole weight: 263.64. | |
(R)-7-Ethyl-10-Hydroxy Camptothecin Quick inquiry Where to buy Suppliers range | R-Enantiomer of SN-38. Used for making the bioconjugates and bifunctional isocyanate cross linking reagents. Synonyms: (4R)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione. Grades: > 95%. CAS No. 647852-82-2. Molecular formula: C22H20N2O5. Mole weight: 392.42. | |
Sandramycin Quick inquiry Where to buy Suppliers range | Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity. Synonyms: (-)-Sandramycin; 3-Hydroxy-N-[23-[(3-hydroxyquinoline-2-carbonyl)amino]-8, 11, 28, 31-tetramethyl-2, 6, 9, 12, 15, 22, 26, 29, 32, 35-decaoxo-7, 27-di(propan-2-yl)-5, 25-dioxa-1, 8, 11, 14, 21, 28, 31, 34-octazatricyclo[34.4.0.016, 21]tetracontan-3-yl]quinoline-2-carboxamide. Grades: ≥95%. CAS No. 100940-65-6. Molecular formula: C60H76N12O16. Mole weight: 1221.32. | |
Saquinavir Quick inquiry Where to buy Suppliers range | Saquinavir. Group: Heterocyclic Organic Compound. Alternative Names: n1-[ (1s, 2r) -3-[ (3s, 4as, 8as) -3-[[ (1, 1-dimethylethyl) amino]carbonyl]octahydro-2 (1h) -isoquinolinyl]-2-hydroxy-1- (phenylmethyl) propyl]-2-[ (2-quinolinylcarbonyl) amino]-butanediamide; SAGUINAVIR; SAQUINAVIR; 2-[[2-METHYL-3- (TRIFLUOROMETHYL) PHENYL]AMINO]PYRIDINE-3-CARBOXYLIC ACID; (2S)-N-[ (2S, 3R)-4-[ (3S, 4AS, 8AS)-3- (TERT-BUTYLCARBAMOYL)-3, 4, 4A, 5, 6, 7, 8, 8A-OCTAHYDRO-1H-ISOQUINOLIN-2-YL]-3-HYDROXY-1-PHENYL-BUTAN-2-YL]-2- (QUINOLINE-2-CARBONYLAMINO)BUTANEDIAMIDE; FLUNIXIN; FLUNIXINE; SAQUINAVIRMESYLATE (SUBJECTTOPATENTFREE). CAS No. 127779-20-8. Molecular formula: C38H50N6O5. Mole weight: 670.84. | |
Saquinavir-d9 Quick inquiry Where to buy Suppliers range | Labeled Saquinavir. A selective HIV protease inhibitor. Antiviral. Group: Biochemicals. Alternative Names: (2S) -N1 [ (1S, 2R) -3- [ (3S, 4aS, 8aS) -3- [ [ (1, 1-Dimethylethyl) amino] carbonyl] octahydro-2- (1H) -isoquinolinyl] -2-hydroxy-1- (phenylmethyl) propyl] -2- [ (2-quinolinylcarbonyl) amino] butanediamide-d9; Fortovase-d9; Invirase-d9; Ro 31-8959-d9. Grades: Highly Purified. CAS No. 1356355-11-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Saquinavir Hydroxy-tert-butylamide Quick inquiry Where to buy Suppliers range | Saquinavir Hydroxy-tert-butylamide. Group: Biochemicals. Alternative Names: (2S) -N1-[ (1S, 2R) -2-Hydroxy-3-[ (3S, 4aS, 8aS) -octahydro-3-[[ (2-hydroxy-1, 1-dimethylethyl) amino]carbonyl]-2 (1H) -isoquinolinyl]-1- (phenylmethyl) propyl]-2-[ (2-quinolinylcarbonyl) amino]-butanediamide. Grades: Highly Purified. CAS No. 438200-34-1. Pack Sizes: 1mg. Molecular Formula: C38H50N6O6, Molecular Weight: 686.84. US Biological Life Sciences. | Worldwide |
(S)-Indacaterol Quick inquiry Where to buy Suppliers range | An isomerous impurity of Indacaterol. Indacaterol is an ultra-long-acting β-adrenoceptor agonist used as an oral inhaled bronchodilator. It is indicated for the treatment of patients with chronic obstructive pulmonary disease (COPD). Synonyms: 5-[(1S)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone. Grades: 95%. CAS No. 1235445-80-3. Molecular formula: C24H28N2O3. Mole weight: 392.499. |