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| Product | Description | |
|---|---|---|
| Hydroxyfasudil | Hydroxyfasudil, formed through the metabolism action of Fasudil, could be useful in improving the symptoms of pulmonary hypertension for playing the role as an active Rho-kinase inhibitor and vasodilator. IC50: 0.12 uM and 0.17 uM for ROCK1 and ROCK2, res. Uses: Hydroxyfasudil could be useful in improving the symptoms of pulmonary hypertension for playing the role as an active rho-kinase inhibitor and vasodilator. Synonyms: 5-(1,4-Diazepane-1-sulfonyl)-1,2-dihydroisoquinolin-1-one;1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine;Hydroxyfasudil. Grades: >99 %. CAS No. 105628-72-6. Molecular formula: C14H17N3O3S. Mole weight: 307.37. |  |
| Hydroxyfasudil - CAS 155558-32-0 | A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Group: Fluorescence/luminescence spectroscopy. |  |
| Hydroxyfasudil hydrochloride | Hydroxyfasudil hydrochloride. Group: Biochemicals. Alternative Names: 1- (1-Hydroxy-5-isoquinolinesulfonyl) homopiperazine hydrochloride; 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone; HA1100 hydrochloride. Grades: Highly Purified. CAS No. 155558-32-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C14H18ClN3O3S. US Biological Life Sciences. |  Worldwide |
| Hydroxyfasudil hydrochloride | Hydroxyfasudil hydrochloride is a ROCK inhibitor, with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine Hydrochloride; 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone; HA1100 Hydrochloride. Product Category: Inhibitors. Appearance: Off-White Solid. CAS No. 155558-32-0. Molecular formula: C14H18ClN3O3S. Mole weight: 343.83. Purity: 0.9888. Product ID: ACM155558320. Alfa Chemistry ISO 9001:2015 Certified. Categories: Hydroxyfasudil monohydrochloride. |  |
| Hydroxyfasudil Hydrochloride | Hydroxyfasudil Hydrochloride, an active metabolite of Fasudil, preferentially inhibits Rho-kinase and plays a central role in the pathogenesis of coronary artery spasm. It is reported to inhibit neutrophil migration and exhibit potent vasodilatory effects in vivo. Synonyms: HA 1100 hydrochloride; HA1100 hydrochloride; HA-1100 hydrochloride; 5-(1,4-diazepan-1-ylsulfonyl)-2~{H}-isoquinolin-1-one hydrochloride; 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine hydrochloride. Grades: >98%. CAS No. 155558-32-0. Molecular formula: C14H18ClN3O3S. Mole weight: 343.826. | |
| Hydroxyfasudil hydrochloride hydrate | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
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