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| Product | Description | |
|---|---|---|
| I-BET151 | I-BET151 (GSK1210151A) is a BET bromodomain inhibitor which inhibits BRD4 , BRD2 , and BRD3 with pIC 50 of 6.1, 6.3, and 6.6, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK1210151A. CAS No. 1300031-49-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13235. |  |
| I-BET151 | I-BET151 is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. It was shown to induce early cell cycle arrest and apoptosis in human and mouse MLL-fusion leukemia cell lines. Synonyms: GSK1210151A; 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one. Grades: >98%. CAS No. 1300031-49-5. Molecular formula: C23H21N5O3. Mole weight: 415.453. |  |
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