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| Product | Description | |
|---|---|---|
| Iberdomide | Iberdomide, also known as CC-220, is potentially for the treatment of systemic lupus erythematosus. Iberdomide significantly reduced Ikaros and Aiolos protein levels in B cells, T cells and monocytes. In SLE PBMC cultures, iberdomide inhibited anti-dsDNA and anti-phospholipid autoantibody production (IC50 ?10?nM). Uses: Designed for use in research and industrial production. Additional or Alternative Names: CC-220; CC220; CC 220; Iberdomide. Product Category: Others. Appearance: Solid powder. CAS No. 1323403-33-3. Molecular formula: C25H27N3O5. Mole weight: 449.5. Purity: >98%. IUPACName: (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione. Canonical SMILES: O=C([C@@H](N(CC1=C2C=CC=C1OCC3=CC=C(CN4CCOCC4)C=C3)C2=O)CC5)NC5=O. Product ID: ACM1323403333. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Iberdomide | Iberdomide (CC-220) is a cereblon modulator with an IC50 of 60 nM. It has antitumor and immunomodulatory activities. Synonyms: (3S)-3-[7-[[4-(morpholin-4-ylmethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione; CC-220; CC220; CC 220; Iberdomide. CAS No. 1323403-33-3. Molecular formula: C25H27N3O5. Mole weight: 449.5. |  |
| Iberdomide | Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC 50 of ~150?nM for cereblon-binding affinity. Iberdomide, a derivative of Thalidomide (HY-14658), has antitumor and immunostimulatory activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-220. CAS No. 1323403-33-3. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101291. |  |
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