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| Product | Description | |
|---|---|---|
| Ibiglustat | Ibiglustat is a selective Glucosylceramide synthase inhibitor. It can block the formation of glucosylceramide (GL-1) which is a key intermediate in the synthesis of GL-3. In Oct 2016, Genzyme completed a phase II trial in Fabry's disease (Treatment-naïve) in USA, Czech Republic, France, Poland, Russia and the UK. Phase-II clinical trials in Gaucher's disease in USA is on-going. Uses: Fabry's disease; gaucher's disease. Synonyms: GZ-402671; GZ402671; GZ 402671; SSAR402671; SAR-402671; SAR 402671; Genz-682452-AA; Ibiglustat; GZ-452; Genz-682452; GZ 452; Genz 682452; GZ452; Genz682452; (3S)-1-azabicyclo[2.2.2]octan-3-yl N-{2-[2-(4-fluorophenyl)- 1,3-thiazol-4-yl]propan-2-yl}carbamate. Grades: 98%. CAS No. 1401090-53-6. Molecular formula: C20H24FN3O2S. Mole weight: 389.49. |  |
| Ibiglustat | Ibiglustat (Venglustat) is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Venglustat; SAR402671; GZ402671. CAS No. 1401090-53-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16743. |  |
| Ibiglustat succinate | Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat succinate can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Venglustat succinate; SAR402671 succinate; GZ402671 succinate. CAS No. 1629063-80-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16743B. | |
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