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ICI 63197 ICI 63197. Group: Biochemicals. Grades: Purified. CAS No. 27277-00-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
ICI 63197 ICI 63197 is a specific and potent cAMP phosphodiesterase IV (PDE 4) inhibitor. Its IC50 value is 35 nM for inhibition of [3H]-rolipram binding to rat brain. It is potent in anatagonizing reserpine-induced hypothermia. It has an antidepressant effect following systemic administration in vivo. Synonyms: ICI 63197; ICI63197; ICI-63197; 2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one; 2-Amino-4,5-dihydro-6-methyl-4-propyl-s-triazolo[1,5-a]pyrimidin-5-one. Grades: ≥99% by HPLC. CAS No. 27277-00-5. Molecular formula: C9H13N5O. Mole weight: 207.23. BOC Sciences 9

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