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| Product | Description | |
|---|---|---|
| Bovine Colostrum 30% IgG Powder | Bovine Colostrum 30% IgG Powder. |  CA, FL & NJ |
| Surface IgG (sA20-Ig) of A20 (106-114) | Surface IgG (sA20-Ig) of A20 (106-114) is a peptide corresponding to residues 106-114 of Surface IgG (sA20-Ig) of A20. Inoculation of the Id-peptide in A20-engrafted mice caused apoptosis of tumor cells and resulted in tumor growth inhibition and extended survival of diseased animals. Synonyms: Surface IgG (sA20-Ig) of A20 B-lymphoma cell line (106-114). |  |
| 17-HDHA | 17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27 + CD38 + antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90780-52-2. Pack Sizes: 25 μg (290.28 μM * 250 μL in Ethanol); 50 μg (290.28 μM * 500 μL in Ethanol); 100 μg (290.28 μM * 1 mL in Ethanol). Product ID: HY-113512. |  |
| 1-Vinylnaphthalene | 1-Vinylnaphthalene. Group: other materials. Alternative Names: naphthalene,1-ethenyl-; α-vinylnaphthalene; ALPHA-VINYLNAPHTHALENE; 1-VINYLNAPHTHALENE; 1-ETHENYLNAPHTHALENE; 1-Vinylnaphthalene (stabilized with TBC); (Naphthalen-1-yl)ethene; 1-(1-Naphtyl)ethene. CAS No. 826-74-4. Product ID: 1-ethenylnaphthalene. Molecular formula: 154.21g/mol. Mole weight: C12H10. C=CC1=CC=CC2=CC=CC=C21. InChI=1S / C12H10 / c1-2-10-7-5-8-11-6-3-4-9-12 (10) 11 / h2-9H, 1H2. IGGDKDTUCAWDAN-UHFFFAOYSA-N. |  |
| 1-Vinylnaphthalene (stabilized with TBC) | 1-Vinylnaphthalene may be used in the synthesis of 1-naphthyl-1,2-ethanediol, which can further be utilized as a metal hydrogenated catalyst. It may also be used as a substrate material to produce azidocyanation based products. Group: Small molecule semiconductor building blocksmonomers. CAS No. 826-74-4. Product ID: 1-ethenylnaphthalene. Molecular formula: 154.21. Mole weight: C12H10. C=CC1=CC=CC2=CC=CC=C21. InChI=1S / C12H10 / c1-2-10-7-5-8-11-6-3-4-9-12 (10) 11 / h2-9H, 1H2. IGGDKDTUCAWDAN-UHFFFAOYSA-N. >95.0%(GC). | |
| 9-(2-Carboxy-2-cyanovinyl)julolidine | 9-(2-Carboxy-2-cyanovinyl)julolidine is a fluorescent molecular rotor. 9-(2-Carboxy-2-cyanovinyl)julolidine can be used to bind to IgG and Fab, and preparing antibodies [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 142978-18-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D0054. | |
| Abatacept | Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains) [1]. Abatacept is a selective T-cell co-stimulation modulator and a protein agent for the autoimmune diseases [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CTLA4lg; BMS-188667. CAS No. 332348-12-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108829. | |
| Abatacept (powder) | Abatacept (CTLA4lg; BMS-188667) powder is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). Abatacept powder is a selective T-cell co-stimulation modulator and a protein agent for the autoimmune diseases [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CTLA4lg (powder); BMS-188667 (powder). CAS No. 332348-12-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108829A. | |
| Abelacimab | Abelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MAA868. CAS No. 2098724-83-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99415. | |
| Abiprubart | Abiprubart is an anti- CD40 human IgG4 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2765071-95-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990726. | |
| Abituzumab | Abituzumab (DI17E6) is a humanised anti- integrin αV monoclonal antibody (IgG2 type). Abituzumab effectively reduces the phosphorylation of FAK , Akt and ERK. Abituzumab can be used in cancer research, particularly in prostate cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EMD 525797; DI17E6. CAS No. 1105038-73-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99183. | |
| Adakitug | Adakitug (BMS-986253) is a CHO-expressed human antibody targeting CXCL8/IL-8. Adakitug contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 144.94 kDa. The isotype control for Adakitug can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-986253; HuMax-IL-8. CAS No. 2231258-73-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990598. | |
| Adalimumab | Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor?α ( TNF-α ). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human TNF-alpha, Human Antibody. CAS No. 331731-18-1. Pack Sizes: 1 mg; 5 mg; 25 mg; 50 mg. Product ID: HY-P9908. | |
| Adebrelimab | Adebrelimab (SHR-1316) is a humanized IgG4 monoclonal PD-L1 ( PD-1/PD-L1 ) antibody. Adebrelimab has promising antitumor activity in solid tumors including extensive-stage small-cell lung cancer (SCLC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SHR-1316. CAS No. 2247114-85-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99422. | |
| Adecatumumab | Adecatumumab (Anti-Human EPCAM Recombinant Antibody; MT201) is a full human monoclonal antibody of the IgG1 isotype, targeting human EpCAM. Adecatumumab is expressed in almost all adenocarcinomas, and its activity is not dependent of K-Ras status [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MT 201; Anti-Human EPCAM Recombinant Antibody. CAS No. 503605-66-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99278. | |
| Adintrevimab | Adintrevimab (ADG 20) is a human IgG1 monoclonal SARS-CoV ( SARS-CoV ) antibody. Adintrevimab inhibits SARS-CoV-2 variants and other SARS-like coronaviruses with pandemic potential [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ADG 20. CAS No. 2516243-54-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99423. | |
| Aflibercept | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801. | |
| Aflibercept (VEGF Trap) | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801A. | |
| Alnuctamab | Alnuctamab (EM901) is an asymmetric 2-arm, humanized IgG T-cell engager (TCE). Alnuctamab can be used for immune research, serving as a B-cell maturation antigen (BCMA) x CD3 T-cell engager (TCE). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EM901; CC-93269. CAS No. 2296827-07-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99430. | |
| AM-9635 | AM-9635 is a selective Phosphatidylinositol-3-kinase delta (PI3Kδ) inhibitor. AM-9635 exhibits good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-9635 can inhibit KLH-specific IgG and IgM in a dosedependent manner and it is well tolerated at all doses. AM-96352 shows significantly reduced IgG and IgM specific antibodies. Synonyms: AM-9635; AM 9635; AM9635. (S)-4-amino-6-((1-(6-fluoro-1-(5-fluoropyridin-3-yl)-1H-benzo[d]imidazol-2-yl)ethyl)amino)pyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1338483-10-5. Molecular formula: C19H14F2N8. Mole weight: 392.36. | |
| Amatuximab | Amatuximab (MORab-009) is a chimeric, humanized IgG1/k MAb that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein, which is present in a restricted set of normal adult tissues such as the mesothelium [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MORab-009. CAS No. 931402-35-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99006. | |
| Amubarvimab | Amubarvimab (BRII-196) is a human IgG1 mAb that bind to non-competing epitopes on the receptor binding domain (RBD) of spike protein , with a K D of 5.88 nM. Amubarvimab can effectively neutralize SARS-CoV-2 variants [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BRII-196. CAS No. 2509447-07-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99435. | |
| Andecaliximab | Andecaliximab is a recombinant chimeric IgG4 monoclonal antibody (mAb) targets matrix metalloproteinase 9 ( MMP9 ). Andecaliximab shows the antifibrotic efficacy in idiopathic pulmonary fibrosis mouse models. Andecaliximab can be used for the research of gastric adenocarcinoma and idiopathic pulmonary fibrosis (IPF) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-MMP9 Reference Antibody (andecaliximab). CAS No. 1518996-49-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99351. | |
| Anselamimab | Anselamimab (CAEL-101) a humanized IgG1-κ anti-Amyloid fibrils antibody targeting to serum amyloid A1 ( SAA1 ) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CAEL-101. CAS No. 2414866-63-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99105. | |
| Ansuvimab | Ansuvimab (Ansuvimab-zyk) is a recombinant human monoclonal IgG1 antibody that exhibits antiviral activity against Zaire ebolavirus. Ansuvimab binds to the glycoprotein on Zaire ebolavirus to block its entry into host cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Ansuvimab-zyk; mAb114. CAS No. 2375952-29-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99337. | |
| Ascrinvacumab | Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a K d value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-ACVRL1 / ALK-1 Reference Antibody (ascrinvacumab); PF-03446962. CAS No. 1463459-96-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99353. | |
| Astegolimab | Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2 , the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MSTT 1041A; RG 6149. CAS No. 2173054-79-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99444. | |
| Atacicept | Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B lymphocyte stimulator and a proliferation-inducing ligand. Atacicept can be used in research of B-cell autoimmune disease [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TACI-Ig; TACI-Fc 5. CAS No. 845264-92-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99446. | |
| Atezolizumab | Atezolizumab (MPDL3280A) is a selective humanized monoclonal IgG1 antibody against programmed death ligand 1 ( PD-L1 ), used for cancer research. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MPDL3280A. CAS No. 1380723-44-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9904. | |
| Avdoralimab | Avdoralimab (IPH 5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) that prevents its binding to C5a. Avdoralimab can be used for complement-driven inflammatory diseases and solid tumours research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IPH 5401; Anti-C5aR1 mAb. CAS No. 2226393-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99450. | |
| Avelumab | Avelumab is a fully human IgG1 anti- PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human PD-L1, Human Antibody; MSB 0010718C; MSB0010718C. CAS No. 1537032-82-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108730. | |
| Avelumab (anti-PD-L1) | Avelumab (anti-PD-L1) is a fully human IgG1 anti- PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1537032-82-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108730A. | |
| Avizakimab | Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BOS161721. CAS No. 2229685-51-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99451. | |
| Axatilimab | Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SNDX-6352. CAS No. 2155851-88-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99452. | |
| Azintuxizumab | Azintuxizumab is an anti- SLAMF7 human IgG4κ monoclonal antibody. Azintuxizumab can be used in the synthesis of antibody-drug conjugate (ADC), Azintuxizumab vedotin [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1826819-57-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99453. | |
| Balstilimab | Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AGEN2034. CAS No. 2148321-77-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99457. | |
| Barzolvolimab | Barzolvolimab (CDX 0159) is a humanized anti- KIT IgG1 monoclonal antibody. Barzolvolimab specificity and potently inhibits KIT activation by SCF. Barzolvolimab can reduce skin mast cells and disease activity in chronic inducible urticaria [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CDX-0159; CDX-0158. CAS No. 2438203-51-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99462. | |
| Basiliximab | Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti- interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CHI 621. CAS No. 179045-86-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108852. | |
| Batoclimab | Batoclimab is a human anti- FcRn monoclonal antibody. Batoclimab can be used for the research of autoimmune diseases mediated by pathogenic IgG antibodies [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HBM9161; IMVT-1401. CAS No. 2187430-05-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99009. | |
| Batoclimab | Batoclimab is a humanized monoclonal antibody targeting the neonatal Fc receptor (FcRn). Batoclimab binds to and inhibits FcRn, thus blocking the recycling of IgG antibodies. Batoclimab can be used in the research of pathogenic IgG-mediated autoimmune diseases. Synonyms: HBM9161; IMVT-1401. CAS No. 2187430-05-1. | |
| Bebtelovimab | Bebtelovimab a humanized IgG1-λ2 antibody targeting to SARS-CoV-2 , especially COVID-19. Bebtelovimab potently neutralizes SARS-CoV-2 variants, and inhibits COVID-19 with mild-to-moderate efficacy [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY-3853113; LY-COV1404. CAS No. 2578319-11-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99103. | |
| Becotatug | Becotatug (JMT-101) is an IgG1 antibody targeting EGFR that can also be conjugated to Afatinib (HY-10261) and Osimertinib (HY-15772) as a synthetic ADC [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JMT-101. CAS No. 2648260-93-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990049. | |
| Begelomab | Begelomab (SAND-26) is a murine IgG2b monoclonal antibody against DPP-4/CD26. Begelomab can be used for the research of severe refractory idiopathic inflammatory myopathy [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SAND-26. CAS No. 1403744-56-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99466. | |
| Belantamab | Belantamab (GSK2857916) is a humanized IgG1 anti-BCMA/TNFRSF17 monoclonal antibody. Belantamab is linked to MMAF (HY-15579) through a non-cleavable ADC linker to synthesize the antibody-active molecule conjugate (ADC) Belantamab mafodotin (HY-P3239). After binding to BCMA on the surface of tumor cells, Belantamab mafodotin enters the cell through receptor-mediated endocytosis. After entering the cell, Belantamab mafodotin releases MMAF, blocks cell division by inhibiting tubulin polymerization, arrests the cell cycle and induces cell apoptosis. Belantamab can be used for the study of multiple myeloma, especially relapsed/refractory multiple myeloma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GSK2857914. CAS No. 2061894-48-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9980. | |
| Belimumab | Belimumab (LymphoStat B) is a human IgG1λ monoclonal antibody that inhibits B-cell activating factor (BAFF). Belimumab can be used for systemic lupus erythematosus (SLE) research. Group: Inhibitors. Alternative Names: belimumab. CAS No. 356547-88-1. Appearance: Solid. Purity: 0.994. Catalog: ACM356547881. |  |
| Belimumab | Belimumab (LymphoStat B) is a humanized IgG1λ monoclonal antibody against B-lymphocyte stimulator ( BLyS ) protein. Belimumab antagonizes BLyS activity in autoimmune diseases and B-lymphocyte malignancies. Belimumab can be used for systemic lupus erythematosus (SLE) research [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LymphoStat B. CAS No. 356547-88-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P9952. | |
| Bemarituzumab | Bemarituzumab is a first-in-class, humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1952272-74-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99010. | |
| Benufutamab | Benufutamab (GEN1029) is a death receptor 5 (DR5) -specific agonistic antibody. Benufutamab is a mixture of 2 noncompeting DR5-specific IgG1 antibodies, each with an E430G mutation in the Fc domain. Benufutamab has antitumor effects [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GEN1029. CAS No. 2109730-69-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99470. | |
| Bepranemab | Bepranemab (UCB 0107) is a humanized, full-length IgG4 monoclonal antibody that binds to a central tau epitope (amino acids 235-250). Bepranemab can be used for Alzheimers disease (AD) research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: UCB 0107. CAS No. 2244960-75-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99471. | |
| Bevacizumab | Bevacizumab, a humanized IgG1 monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human VEGF, Humanized Antibody. CAS No. 216974-75-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9906. | |
| Bexmarilimab | Bexmarilimab (FP-1305) is a potent humanized anti- CLEVER-1 IgG4-antibody with an IC 50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: FP-1305. CAS No. 2259301-27-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99236. | |
| Bintrafusp alfa | Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: M7824; MSB0011359C. CAS No. 1918149-01-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99480. | |
| BMS-935177 | BMS-935177 is a potent and selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 3 nM and demonstrates good kinase selectivity. It is more potent against BTK than other kinase, including the other Tec family kinases (TEC, BMX, ITK, and TXK) over which the compound is between 5- and 67-fold selective. BMS-935177 inhibited calcium flux in human Ramos B cells with IC50 of 27 nM and inhibited CD69 surface expression in peripheral B cells stimulated with anti-IgM and anti-IgG. Synonyms: BMS-935177; BMS935177. Grades: ≥98%. CAS No. 1231889-53-4. Molecular formula: C31H26N4O3. Mole weight: 502.56. | |
| Brazikumab | Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of IL-23 , with a K D of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 139; MEDI2070. CAS No. 1610353-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99485. | |
| Brodalumab | Brodalumab (AMG 827) is a human anti- interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 827; KHK4827. CAS No. 1174395-19-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9925. | |
| Budigalimab | Budigalimab (ABBV 181; PR 1648817) is a humanized, recombinant IgG1 monoclonal antibody targeting programmed cell death 1 ( PD-1 ) receptor. Budigalimab has an Fc mutation that reduces the inhibition of Fc receptor interactions and effector factors. Budigalimab can block the binding of PD-1 and PD-L1, which has anti-tumor activity. Budigalimab can be used in the study of solid tumors [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABBV 181; PR 1648817. CAS No. 2098225-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99489. | |
| Cadonilimab | Cadonilimab (AK104) is a humanized tetravalent IgG1 bispecific antibody targeting PD1/CTLA4. Cadonilimab blocks both PD-1 and CTLA-4 pathways, thereby relieving their corresponding immunosuppressive effects and reversing tumor specific T cell exhaustion. Cadonilimab significantly downregulates Fc-mediated effector functions, including antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), complement dependent cytotoxicity (CDC). Cadonilimab can be used for research of metastatic cervical cancer, as well as other malignancies such as gastric cancer, GEJ adenocarcinoma and non-small cell lung cancer (NSCLC) [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AK104. CAS No. 2394841-59-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99117. | |
| Camrelizumab | Camrelizumab is an anti-PD-1 immune checkpoint inhibitor that is being investigated for hepatocellular carcinoma and Hodgkin lymphoma. Camrelizumab is a humanized anti-PD-1 IgG4 antibody that blocks the binding of PD-L1 and PD-L2 to PD-1 with immune checkpoint inhibitory and antineoplastic activities. Synonyms: SHR-1210. Grades: ≥98%. | |
| Camrelizumab | Camrelizumab (SHR-1210) is a potent humanied high-affinity IgG4-κ monoclonal antibody (mAb) to PD-1. Camrelizumab binds PD-1 at a high affinity of 3 nM and inhibits the binding interaction of PD-1 and PD-L1 with an IC 50 of 0.70 nM. Camrelizumab acts as anti-PD-1/PD-L1 agent and can be used for cancer research, including NSCLC, ESCC, Hodgkin lymphoma, and advanced HCC et,al [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SHR-1210. CAS No. 1798286-48-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9971. | |
| Carotuximab | Carotuximab (TRC105) is a IgG1 monoclonal antibody that blocks endoglin (CD105) and its downstream Smad signaling pathway. Carotuximab has immunomodulatory and antineoplastic actions [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TRC105; DE-122. CAS No. 1268714-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99494. | |
| Casdozokitug | Casdozokitug (SRF-388) is an IgG1κ antibody targeting IL27 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SRF-388. CAS No. 2643331-37-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990024. | |
| Catumaxomab | Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 509077-98-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9954. | |
| Cemiplimab | Cemiplimab (Anti-Human PD-1) is a high-affinity programmed death receptor-1 ( PD-1 ) monoclonal IgG4 antibody that blocks PD-1/PD-L1-mediated T-cell suppression. Cemiplimab is commonly used in squamous cell skin cancer research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1801342-60-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99203. | |
| Cetrelimab | Cetrelimab (JNJ 63723283; JNJ 3283) is a human IgG4κ mAb targeting PD-1. Cetrelimab binds PD-1 (K d =1.72 nM, HEK293) to block the interaction of PD-1 with PD-L1 and PD-L2 ( IC 50 s=111.7 ng/mL and 138.6 ng/mL, respectively). Cetrelimab stimulates peripheral T cells, increases IFN-γ , IL-2 , TNF-α level and inhibits tumor growth in vivo [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JNJ 63723283; JNJ 3283. CAS No. 2050478-92-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99499. | |
| Cetuximab | Cetuximab (C225) is a human IgG1 monoclonal antibody that inhibits epidermal growth factor receptor ( EGFR ), with a K d of 0.201 nM for EGFR by SPR. Cetuximab has potent antitumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: C225. CAS No. 205923-56-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9905. | |
| Cevostamab | Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized IgG1-based BsAb that targets membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells as well as CD3 on T cells. Moreover, Cevostamab facilitates efficient synapse formation, improves killing activity of T cells against MM tumor cells [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BFCR 4350A; RG 6160; RO 7187797. CAS No. 2249888-53-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99601. | |
| Chi Lob 7/4 | An IgG1 chimeric monoclonal antibody agonist of CD40 with potential immunostimulatory and antineoplastic activities. | |
| CM-24 | CM-24 is a humanized antibody expressed in CHO cells, targeting CEACAM1/CD66a. The predicted molecular weight (MW) of CM-24 is 145 kDa. The isotype control for CM-24 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1783801-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990569. | |
| Cofetuzumab | Cofetuzumab (PF-06523435) is a humanized IgG1-κ monoclonal antibody targeting PTK7. The expression system of Cofetuzumab is usually CHO (Chinese Hamster Ovary) cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-06523435; hu24. CAS No. 1869928-62-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99828. | |
| Cofetuzumab pelidotin | Cofetuzumab pelidotin (PF-06647020) is a PTK7 -targeting ADC comprising a humanized anti-PTK7 mAb (hu6M024, IgG1) joined to an auristatin microtubule inhibitor payload, auristatin-0101 (Aur0101; HY-12522), by a cleavable valine-citrulline (vc)-based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to cell-surface PTK7 with an EC 50 of 1153 pM by flow cytometry. Cofetuzumab pelidotin has the potential for solid tumors research [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-06647020; ABBV-647; h6M24-vc0101. CAS No. 1869937-48-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99829. | |
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