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Product | Description | |
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Bovine Colostrum 30% IgG Powder Quick inquiry Where to buy Suppliers range | Bovine Colostrum 30% IgG Powder. | CA, FL & NJ |
Surface IgG (sA20-Ig) of A20 (106-114) Quick inquiry Where to buy Suppliers range | Surface IgG (sA20-Ig) of A20. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-583. | |
Surface IgG (sA20-Ig) of A20 (106-114) Quick inquiry Where to buy Suppliers range | Surface IgG (sA20-Ig) of A20 (106-114) is a peptide corresponding to residues 106-114 of Surface IgG (sA20-Ig) of A20. Inoculation of the Id-peptide in A20-engrafted mice caused apoptosis of tumor cells and resulted in tumor growth inhibition and extended survival of diseased animals. Synonyms: Surface IgG (sA20-Ig) of A20 B-lymphoma cell line (106-114). | |
1-Vinylnaphthalene (stabilized with TBC) Quick inquiry Where to buy Suppliers range | 1-Vinylnaphthalene (stabilized with TBC). Group: Small Molecule Semiconductor Building Blocks; Monomers. CAS No. 826-74-4. IUPAC Name: 1-ethenylnaphthalene. Molecular Weight: 154.21g/mol. Molecular Formula: C12H10. SMILES: C=CC1=CC=CC2=CC=CC=C21. InChI: InChI=1S/C12H10/c1-2-10-7-5-8-11-6-3-4-9-12(10)11/h2-9H,1H2. InChIKey: IGGDKDTUCAWDAN-UHFFFAOYSA-N. | |
AM-9635 Quick inquiry Where to buy Suppliers range | AM-9635 is a selective Phosphatidylinositol-3-kinase delta (PI3Kδ) inhibitor. AM-9635 exhibits good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-9635 can inhibit KLH-specific IgG and IgM in a dosedependent manner and it is well tolerated at all doses. AM-96352 shows significantly reduced IgG and IgM specific antibodies. Synonyms: AM-9635; AM 9635; AM9635. (S)-4-amino-6-((1-(6-fluoro-1-(5-fluoropyridin-3-yl)-1H-benzo[d]imidazol-2-yl)ethyl)amino)pyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1338483-10-5. Molecular formula: C19H14F2N8. Mole weight: 392.36. | |
Batoclimab Quick inquiry Where to buy Suppliers range | Batoclimab is a humanized monoclonal antibody targeting the neonatal Fc receptor (FcRn). Batoclimab binds to and inhibits FcRn, thus blocking the recycling of IgG antibodies. Batoclimab can be used in the research of pathogenic IgG-mediated autoimmune diseases. Synonyms: HBM9161; IMVT-1401. CAS No. 2187430-05-1. | |
BMS-935177 Quick inquiry Where to buy Suppliers range | BMS-935177 is a potent and selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 3 nM and demonstrates good kinase selectivity. It is more potent against BTK than other kinase, including the other Tec family kinases (TEC, BMX, ITK, and TXK) over which the compound is between 5- and 67-fold selective. BMS-935177 inhibited calcium flux in human Ramos B cells with IC50 of 27 nM and inhibited CD69 surface expression in peripheral B cells stimulated with anti-IgM and anti-IgG. Synonyms: BMS-935177; BMS935177. Grades: ≥98%. CAS No. 1231889-53-4. Molecular formula: C31H26N4O3. Mole weight: 502.56. | |
Camrelizumab Quick inquiry Where to buy Suppliers range | Camrelizumab is an anti-PD-1 immune checkpoint inhibitor that is being investigated for hepatocellular carcinoma and Hodgkin lymphoma. Camrelizumab is a humanized anti-PD-1 IgG4 antibody that blocks the binding of PD-L1 and PD-L2 to PD-1 with immune checkpoint inhibitory and antineoplastic activities. Synonyms: SHR-1210. Grades: ≥98%. | |
Chi Lob 7/4 Quick inquiry Where to buy Suppliers range | An IgG1 chimeric monoclonal antibody agonist of CD40 with potential immunostimulatory and antineoplastic activities. | |
CP-870893 Quick inquiry Where to buy Suppliers range | CP-870893 is a potent and selective agonist of CD40 and a fully human IgG2 mAb. Synonyms: CP-870,893; CP 870,893; CP870,893; CP870893. | |
Daclizumab Quick inquiry Where to buy Suppliers range | Daclizumab is a humanized monoclonal antibody of the human IgG1 isotype that binds specifically to the Tac epitope on the α-subunit (CD25) of the IL-2R. Synonyms: Zenapax; Ro 24-7375. CAS No. 152923-56-3. Molecular formula: C6332H9808N1678O1989S42. Mole weight: 142612.1. | |
Daratumumab Quick inquiry Where to buy Suppliers range | Daratumumab is a recombinant IgG1k monoclonal antibody that binds to CD38 and leads to cell apoptosis. Daratumumab was granted orphan drug designation for the treatment of multiple myeloma, diffuse large B cell lymphoma, follicular lymphoma, and mantle cell lymphoma. Uses: Antitumor agent. Synonyms: Darzalex; HuMax-CD38; UNII-4Z63YK6E0E. CAS No. 945721-28-8. Molecular formula: C6466H9996N1724O2010S42. Mole weight: 145391.67. | |
DC-Chol Liposome Quick inquiry Where to buy Suppliers range | DC-Chol is synthesized from N',N'-dimethylethylenediamine and chloroformylated cholesterol. The liposome contains DC-Chol and can be used as a vaccine adjuvant. Its combination with genetically engineered hepatitis B surface antigen increases the levels of specific antibodies IgG1, IgG2a and Th1 and Th2 class cytokines. It is only for research purposes. Group: Liposomal vaccine or adjuvant. | |
Denosumab Quick inquiry Where to buy Suppliers range | Denosumab is a fully human sequence IgG2 monoclonal antibody that inhibits bone resorption by blocking the activity of receptor activator of nuclear factor-κB ligand (RANKL). Synonyms: D03684; D 03684; D-03684; Denosumab; Denosumab (usan). Grades: 95%. CAS No. 615258-40-7. Molecular formula: C6404H9908N1724O2004S50. Mole weight: 144716.86. | |
Dulaglutide Quick inquiry Where to buy Suppliers range | Dulaglutide is a novel glucagon-like peptide-1 agonist (GLP-1) biologic drug consisting of a dipeptidyl peptidase-IV-protected GLP-1 analogue covalently linked to a human IgG4-Fc heavy chain by a small peptide linker. Uses: API. CAS No. 923950-08-7. Product ID: 10-101-159. | |
durvalumab Quick inquiry Where to buy Suppliers range | Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody. It was approved by FDA for the treatment of patients with locally advanced or metastatic urothelial carcinoma who have disease progression during or following platinum-containing chemotherapy, or whose disease has progressed within 12 months of receiving platinum-containing chemotherapy before or after surgery. Uses: The treatment of locally advanced or metastatic urothelial carcinoma. Synonyms: Imfinzi. CAS No. 1428935-60-7. Molecular formula: C6502H10018N1742O2024S42. Mole weight: 146.3. | |
Eculizumab Quick inquiry Where to buy Suppliers range | Eculizumab is a recombinant human IgG2/4κ monoclonal antibody used for the treatment of paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS). Eculizumab acts as a terminal complement inhibitor that binds to the terminal complement component 5, or C5 and suppresses the complement cascade. Uses: The treatment of pnh and ahus. Synonyms: Soliris. CAS No. 219685-50-4. | |
Ganglioside GQ1b, Tetrasialo, Tetraammonium Salt, Bovine Brain Quick inquiry Where to buy Suppliers range | Ganglioside GQ1b enhances spontaneous IgG, IgM, and IgA production in human peripheral monocytic cells. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 100μG. Mole weight: 2488.71. Catalog: IAR42410773. Assay: ≥98% (TLC). | |
Glembatumumab Quick inquiry Where to buy Suppliers range | Glembatumumab is a human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be linked to monomethyl auristatin E (MMAE) to form Glembatumumab vedotin, an ADC for cancer therapy. Synonyms: Anti-GPNMB. CAS No. 1020264-78-1. | |
H-Ser-Leu-Ser-Leu-Ser-Pro-Gly-OH Quick inquiry Where to buy Suppliers range | H-Ser-Leu-Ser-Leu-Ser-Pro-Gly-OH, a peptide from the C-terminus of the human Ig Gamma-1 chain C region, is used for structural characterization of recombinant hybrid IgG molecules by MS analysis of tryptic digests. Synonyms: L-seryl-L-leucyl-L-seryl-L-leucyl-L-seryl-L-prolyl-glycine. Grades: ≥95%. CAS No. 943235-75-4. Molecular formula: C28H49N7O11. Mole weight: 659.74. | |
Humanized IgG1k Monoclonal Antibody Quick inquiry Where to buy Suppliers range | Humanized IgG1k Monoclonal Antibody. Uses: For analytical and research use. Group: Building Blocks. Catalog: APS008837. Shipping: Dry ice. | |
Immunoglobulin for anti-A, anti-B antibodies limit test BRP Quick inquiry Where to buy Suppliers range | Immunoglobulin for anti-A, anti-B antibodies limit test BRP. Uses: For analytical and research use. Group: European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. Alternative Names: IGG. Catalog: APS008945. Format: Mixture. Product Type: Other. Shipping: Ice pack (-20°C). | |
Ivuxolimab Quick inquiry Where to buy Suppliers range | Ivuxolimab is a humanized agonistic IgG2 monoclonal antibody. Ivuxolimab selectively binds to OX40, resulting in proliferation of memory and effector T lymphocytes. Synonyms: PF-04518600; PF 04518600; PF04518600. CAS No. 2128729-41-7. | |
Ixazomib Quick inquiry Where to buy Suppliers range | Ixazomib is a proteasome inhibitor and the biologically active form of MLN9708. Ixazomib exhibits an improved pharmacodynamic profile and antitumor activity compared with bortezomib in both OCI-Ly10 and PHTX22L models. Although both Ixazomib and bortezomib prolonged overall survival, reduced splenomegaly, and attenuated IgG2a levels in the iMyc(Cα)/Bcl-X(L) GEM model, only Ixazomib alleviated osteolytic bone disease in the DP54-Luc model. Synonyms: MLN2238; MLN-2238; MLN 2238; Ixazomib. Trade name: Ninlaro. (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)boronic acid. Grades: > 95%. CAS No. 1072833-77-2. Molecular formula: C14H19BCl2N2O4. Mole weight: 361.026. | |
KF 38789 Quick inquiry Where to buy Suppliers range | KF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion with IC50 value of 1.97 μM. It shows no effects on E-selectin-mediated and L-selectin- adhesion. It blocks leukocyte accumulation in vivo and P-selectin-mediated binding in vitro. It also inhibits the binding of U937 cells to immobilized P-selectin IgG chimeric protein with an IC50 value of 1.97 μM. Synonyms: KF 38789; KF38789; KF-38789; 3-[7-(2,4-Dimethoxyphenyl)-2,3,6,7-tetrahydro-1,4-thiazepin-5-yl]-4-hydroxy-6-methyl-2H-pyran-2-one. Grades: ≥97% by HPLC. CAS No. 257292-29-8. Molecular formula: C19H21NO5S. Mole weight: 375.44. | |
MGA271 Quick inquiry Where to buy Suppliers range | Enoblituzumab is a monoclonal antibody designed for the treatment of cancer. Formerly known as MGA271, the drug is a humanized IgG1κ monoclonal antibody recognizing human. B7-H3, a member of the B7 family of immune regulators. Synonyms: MGA271; MGA 271; MGA-271; Enoblituzumab; UNII-M6030H73N9. CAS No. 1353485-38-7. Molecular formula: C6474H9990N1726O2030S42. | |
Necitumumab Quick inquiry Where to buy Suppliers range | Necitumumab is a human IgG1 monoclonal antibody that binds to EGFR. Necitumumab has been approved for the treatment of squamous NSCLC. Synonyms: Portrazza. CAS No. 906805-06-9. | |
nivolumab Quick inquiry Where to buy Suppliers range | Nivolumab, marketed as Opdivo, is a humanized IgG4 anti-PD-1 monoclonal antibody used to treat cancer. Nivolumab works as a checkpoint inhibitor, blocking a signal that would have prevented activated T cells from attacking the cancer, thus allowing the immune system to clear the cancer. Synonyms: Opdivo; ONO-4538; BMS-936558; MDX1106; ONO4538; BMS936558; MDX 1106; ONO 4538; BMS 936558; MDX-1106. CAS No. 946414-94-4. | |
Nylidrin hydrochloride Quick inquiry Where to buy Suppliers range | Nylidrin hydrochloride is a beta-adrenergic agonist. It was an effective inhibitor of IgE-mediated release of histamine from passively sensitized rat peritoneal mast cells and human basophils, and of IgG1-mediated release of histamine from passively sensitized guinea pig lung slices. It causes peripheral vasodilation, a positive inotropic effect, and increases gastric volume of gastric juice. It is used in the treatment of peripheral vascular disorders and premature labor. It also can be used as antiallergic agent. It is one of the FDA approved drug as Inhibitors of the Human Sodium Taurocholate Cotransporting Polypeptide (NTCP). Uses: Nylidrin hydrochloride is used in the treatment of peripheral vascular disorders and premature labor. it also can be used as antiallergic agent. Synonyms: 1-p-Hydroxyphenyl-2-(1'-methyl-3'-phenylpropylamino)-1-propanolhydrochloride;Arlidin hydrochloride;Buphenine hydrochloride;Dilatol hydrochloride;p-Hydroxy-alpha-(1-((1-methyl-3-phenylpropyl)amino)ethyl)-benzylalcohohyd;Suprifenpsb hydrochloride; 4-[1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl]phenol; hydrochloride; Dilatyl. Grades: 95%. CAS No. 849-55-8. Molecular formula: C19H26NO2Cl. Mole weight: 335.87. | |
Palmitoyl Tetrapeptide-3 Quick inquiry Where to buy Suppliers range | Palmitoyl Tetrapeptide-3 (Rigin) is a synthetic peptide, corrspending to 341-344 amino acid sequence of IgG human H-chain, with phagocytosis stimulating activity. Uses: Peptide Inhibitors. CAS No. 221227-05-0. Product ID: R1598. | |
Pam3Cys-Ser-(Lys)4 3HCl (Pam3CSK4, Pam3Cys-SKKKK, (S)-[2,3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys4-OH) Quick inquiry Where to buy Suppliers range | Selective agonist of TLR1/TLR2 complex. Cell permeable, water soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Potent and effective immune adjuvant. Exerts strong local response, enhances IgG2a and IgG1 titers and upregulates proinflammatory and Th1 cytokine genes. Potent activator of the proinflammatory transcription factor NF-kappaB. Activates/represses at least 140 genes involved in signal transduction and regulation of the immune response. Group: Biochemicals. Alternative Names: Pam3CSK4, Pam3Cys-SKKKK, (S)-[2,3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys4-OH. Grades: Highly Purified. CAS No. 112208-00-1. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
pembrolizumab Quick inquiry Where to buy Suppliers range | Pembrolizumab (formerly MK-3475 and lambrolizumab, trade name Keytruda) is a humanized antibody used in cancer immunotherapy. It targets the programmed cell death 1 (PD-1) receptor. The drug was initially used in treating metastatic melanoma. Synonyms: Anti-PD-1 monoclonal antibody - Merck; Humanised monoclonal IgG4 antibody against PD-1 - Merck; Keytruda; Lambrolizumab; MK-3475; MK 3475; MK3475; SCH-900475; SCH 900475; SCH900475. CAS No. 1374853-91-4. | |
Pertuzumab Quick inquiry Where to buy Suppliers range | Pertuzumab is a humanized IgG1 monoclonal antibody and a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer. Synonyms: pertuzumab; 2C4; Immunoglobulin G1, anti-(human V (receptor)) (human-mouse monoclonal 2C4 heavy chain), disulfide with human-mouse monoclonal 2C4 kappa-chain, dimer; Omnitarg; Unii-K16aiq8ctm. Grades: 95%. CAS No. 380610-27-5. Mole weight: 145175.18. | |
Protein G (3xC), BioSeparation Quick inquiry Where to buy Suppliers range | BioSeparation rProtein G (3xC) is a 25.21kD synthetic derivative of the natural protein G molecule, produced by recombinant expression in E. coli and purified using a highly efficient, immunoglobulin-free process. rProtein G (3xC) comprises the Fc binding domain of natural Protein G, devoid of its BSA-binding region. Immobilized rProtein G (3xC) exhibits strong IgG binding capacity suitable for antibody capture and elution under standard conditions. Group: Molecular Biology. US Biological Life Sciences. | Worldwide |
R406 Quick inquiry Where to buy Suppliers range | R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated activation of Fc receptor signaling (EC(50) for degranulation=56-64 nM). The primary target for R406 is the spleen tyrosine kinase (Syk). R406 inhibited phosphorylation of Syk substrate linker for activation of T cells in mast cells and B-cell linker protein/SLP65 in B cells. R406 bound to the ATP binding pocket of Syk and inhibited its kinase activity as an ATP-competitive inhibitor (K(I)=30 nM). Furthermore, R406 blocked Syk-dependent FcR-mediated activation of monocytes/macrophages and neutrophils and BCR-mediated activation of B lymphocytes. R406 is orally bioavailable, achieving exposures capable of inhibiting Syk-dependent IgE-mediated basophil activation. Collectively, the results show R406 potential for modulating Syk activity in human disease. Synonyms: R 406; R-406. CAS No. 841290-80-0. Molecular formula: C22H23FN6O5. Mole weight: 470.45. | |
Ramucirumab Quick inquiry Where to buy Suppliers range | Ramucirumab is a human IgG1 monoclonal antibody developed by ImClone Systems Inc to treat solid tumors. It has been approved by FDA for the treatment of advanced gastric or gastro-esophageal junction adenocarcinoma and metastatic non-small-cell lung carcinoma (NSCLC). Ramucirumab acts as a VEGFR2 antagonist via binding to VEGFR2. Uses: Antitumor agent. Synonyms: Cyramza; Imc 1121b. Grades: ≥98%. CAS No. 947687-13-0. Molecular formula: C6374H9864N1692O1996S46. Mole weight: 143609.63. | |
Rheumatoid Factor, Control Serum, Human Quick inquiry Where to buy Suppliers range | Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown etiology. Rheumatoid arthritis is a systemic disease characterized by chronic proliferation and inflammation of joint cartilage and supporting structures. RA is mainly defined by clinical criteria, in which systematic pathogenetic studies have been hampered by doubts about the presence of common pathogenetic mechanisms and the relative lack of unique laboratory findings. IgG rheumatoid factor has been reported to be present in sera of patients with rheumatoid arthritis both with and without IgM rheumatoid factor activity. Group: Biologicals. Grades: Serum. Pack Sizes: 2ml. US Biological Life Sciences. | Worldwide |
Rilotumumab Quick inquiry Where to buy Suppliers range | Rilotumumab is a human IgG2 monoclonal antibody that binds to HGF and inhibits c-Met-mediated signal transduction. Rilotumumab has been investigated as the treatment of solid tumors. Synonyms: AMG102; AMG 102; AMG-102. CAS No. 872514-65-3. | |
RN983 Quick inquiry Where to buy Suppliers range | RN983 is a selective BTK enzyme inhibitor. It inhibits IgG production in B-cells with an IC50 value of 2.5?±?0.7?nM and PGD2 production from mast cells with an IC50 value of 8.3?±?1.1?nM. RN983 showed similar activities in the allergic mouse model of asthma. RN983 may be effective as a stand-alone asthma therapy or used in combination with inhaled steroids and β-agonists in severe asthmatics. Uses: Asthma. Synonyms: RN983; RN-983; RN 983. 6-(tert-butyl)-8-fluoro-2-(3-(hydroxymethyl)-4-(1-methyl-5-((5-(1-methylpiperidin-4-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydropyridazin-3-yl)pyridin-2-yl)phthalazin-1(2H)-one. Grades: 98%. CAS No. 1423129-83-2. Molecular formula: C34H37FN8O3. Mole weight: 624.72. | |
(S)-(-)-2-Pyrrolidone-5-carboxylic acid Quick inquiry Where to buy Suppliers range | L-Pyroglutamic acid is an amino acid that is used in the synthesis of peptides. It has also been observed to convert when placed at the N-terminus in vivo to create IgG2 antibodies. Group: Biochemicals. Alternative Names: L-Pyroglutamic Acid. Grades: Highly Purified. CAS No. 98-79-3. Pack Sizes: 100g, 250g, 500g, 1kg, 2Kg. Molecular Formula: C?H?NO?, Molecular Weight: 129.11. US Biological Life Sciences. | Worldwide |
Secukinumab Quick inquiry Where to buy Suppliers range | Secukinumab is a recombinant human IgG1κ monoclonal antibody that specifically binds to and inhibits interleukin (IL)-17A. Secukinumab was developed by Novartis for the treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis. Uses: The treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis. Synonyms: Cosentyx. CAS No. 875356-43-7. Molecular formula: C6584H10134N1754O2042S44. Mole weight: 147944.39. | |
Solanezumab Quick inquiry Where to buy Suppliers range | Solanezumab is a humanized monoclonal IgG1 antibody which is directed against the mid-domain of the Aβ peptide. By sequestering Aβ, shifting equilibria between different species of Aβ, and removing small soluble species of Aβ that are directly toxic to synaptic function, it may exert benefit. Uses: API. CAS No. 955085-14-0. Product ID: 10-101-180. | |
Spartalizumab Quick inquiry Where to buy Suppliers range | Spartalizumab is a humanized anti-PD-1 IgG4 antibody under the development of melanoma treatment. Synonyms: PDR001. CAS No. 1935694-88-4. | |
Tovetumab Quick inquiry Where to buy Suppliers range | Tovetumab is a human IgG2κ monoclonal antibody that binds to human platelet-derived growth factor receptor alpha (PDGFRα) and blocks receptor signal transduction by PDGF ligands. Synonyms: MEDI-575; MEDI 575; MEDI575. CAS No. 1243266-04-7. | |
Urelumab Quick inquiry Where to buy Suppliers range | A fully human IgG4 monoclonal antibody developed for the treatment of cancer and solid tumors targets the CD137 receptor. It specifically binds to and activates CD137-expressing immune cells, stimulating an immune response, in particular a cytotoxic T cell response, against tumor cells. Synonyms: BMS - 663513; BMS 663513; BMS663513. CAS No. 934823-49-1. | |
Zalutumumab Quick inquiry Where to buy Suppliers range | Zalutumumab is a human IgG1 monoclonal antibody directed against EGFR. Zalutumumab binds to EGFR receptor and blocks receptor binding of EGF and TGF-a, inducing apoptosis of EGFR-expressing tumor cells. Synonyms: HuMax-EGFR. CAS No. 667901-13-5. |