Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Ilorasertib | Ilorasertib (ABT-348) is a potent, orally active and ATP-competitive aurora inhibitor with IC 50 s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib also is a potent VEGF , PDGF inhibitor. Ilorasertib has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-348. CAS No. 1227939-82-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16018. |  |
| Ilorasertib | Ilorasertib, also know as ABT-348, is a novel, potent and orally bioavailable inhibitor of the Aurora kinases as well as the VEGF and PDGF families of receptor tyrosine kinases and is currently in Phase I clinical trials. ABT-348 has nanomolar potency (IC50) for inhibiting binding and cellular auto-phosphorylation of Aurora B (7 and 13 nM), C (1 and 13 nM) and A (120 and 189 nM). These results provide the rationale for clinical assessment of ABT-348 as a therapeutic agent in the treatment of cancer. Uses: Antineoplastic agents. Synonyms: ABT-348; Abbott 968660. Grades: 0.98. CAS No. 1227939-82-3. Molecular formula: C25H21FN6O2S. Mole weight: 488.541. |  |
| Ilorasertib hydrochloride | Ilorasertib (ABT-348) hydrochloride is a potent, orally active and ATP-competitive aurora inhibitor with IC 50 s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib hydrochloride also is a potent VEGF , PDGF inhibitor. Ilorasertib hydrochloride has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-348 hydrochloride. CAS No. 1847485-91-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16018A. | |
Our database is helping our users find suppliers everyday.
