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| Product | Description | |
|---|---|---|
| Inavolisib | Inavolisib (GDC-0077) is a potent, orally active, and selective PI3Kα inhibitor ( IC 50 =0.038 nM). Inavolisib exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. Inavolisib is more selective for mutant versus wild-type PI3K&alpha. Inavolisib can be used for the study of breast cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0077; RG6114. CAS No. 2060571-02-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101562. |  |
| Inavolisib | Inavolisib Inhibitor. Uses: Scientific use. Product Category: T15375. CAS No. 2060571-02-8. |  |
| GDC-0077 | Inavolisib, also known as GDC-0077, is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved in cancer growth called PI3K. GDC0077 binds to and inhibits various members of the PI3K family, including activating mutations in the catalytic alpha isoform PIK3CA. PI3K inhibition prevents the activation of the PI3K-mediated signaling pathway and results in the inhibition of growth and survival of PI3K-overexpressing tumor cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GDC-0077; GDC 0077; GDC0077; Inavolisib; RG6114; RG 6114; RG-6114. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2060571-02-8. Molecular formula: C18H19F2N5O4. Mole weight: 407.38. Purity: >98%. IUPACName: (S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide. Canonical SMILES: C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H](C(F)F)COC3=O)=CN2CCO4)C4=C1. Product ID: ACM2060571028. Alfa Chemistry ISO 9001:2015 Certified. |  |
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