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Incyclinide incyclinide, also known as CMT-3 and COL-3, is a MMP inhibitor and achemically-modified tetracycline with potential antineoplastic activity. Incyclinide inhibits matrix metalloproteinases (MMPs), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. This agent also causes mitochondrial depolarization in tumor cells and induces both cellular apoptosis and tissue necrosis. Synonyms: Metastat; 4-dedimethylamino sancycline; CMT-3; CMT 3; CMT3; COL 3; COL3; COL-3. CAS No. 15866-90-7. Molecular formula: C19H17NO7. Mole weight: 371.34. BOC Sciences 11
Incyclinide Incyclinide (CMT-3, COL-3) is a matrix metalloproteinase ( MMP ) inhibitor and inhibiting angiogenesis, tumor growth and invasion, and metastasis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CMT-3; COL-3. CAS No. 15866-90-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13648. MedChemExpress MCE

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