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| Product | Description | |
|---|---|---|
| Indacaterol | Indacaterol. Group: Biochemicals. Alternative Names: 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone; QAB 149. Grades: Highly Purified. CAS No. 312753-06-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C24H28N2O3. US Biological Life Sciences. |  Worldwide |
| Indacaterol | Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312753-06-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14299. |  |
| Indacaterol Acetate | Indacaterol Acetate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1000160-96-2. Molecular formula: C26H32N2O5. Mole weight: 452.55. Catalog: APB1000160962. |  |
| Indacaterol maleate | Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol maleate inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QAB149. CAS No. 753498-25-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14299A. | |
| Indacaterol Maleate | Indacaterol Maleate. Group: Biochemicals. Grades: Highly Purified. CAS No. 753498-25-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C24H28N2O3·C4H4O4. US Biological Life Sciences. | Worldwide |
| Indacaterol (maleate) (Standard) | Indacaterol (maleate) (Standard) is the analytical standard of Indacaterol (maleate). This product is intended for research and analytical applications. Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol maleate inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 753498-25-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14299AR. | |
| Indacaterol Maleic Acid Salt | A long-acting β2 adrenoreceptor agonist and bronchodilator, for the treatment of asthma and chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone Maleic Acid; QAB 149 Maleic Acid; Onbrez. Grades: Highly Purified. CAS No. 753498-25-8. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Benzyl Indacaterol | An impurity of Indacaterol. Indacaterol is an ultra-long-acting β2-adrenoceptor agonist used as an oral inhaled bronchodilator. It is indicated for the treatment of patients with chronic obstructive pulmonary disease (COPD). Synonyms: O-Benzyl Indacaterol; 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone; (R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-one; (R)-8-(Benzyloxy)-5-[2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-1H-quinolin-2-one; Indacaterol Impurity 7. Grade: ≥95%. CAS No. 435273-75-9. Molecular formula: C31H34N2O3. Mole weight: 482.61. |  |
| Benzyl Indacaterol succinate | An impurity of Indacaterol. Indacaterol is an ultra-long-acting β2-adrenoceptor agonist used as an oral inhaled bronchodilator. It is indicated for the treatment of patients with chronic obstructive pulmonary disease (COPD). Synonyms: Butanedioic acid, compd. with 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone (1:1); (R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-one succinate salt; 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone succinate salt; (R)-8-(Benzyloxy)-5-[2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-1H-quinolin-2-one succinate salt. Grade: ≥95%. CAS No. 753498-31-6. Molecular formula: C31H34N2O3.C4H6O4. Mole weight: 600.70. | |
| (S)-Indacaterol | An isomerous impurity of Indacaterol. Indacaterol is an ultra-long-acting β-adrenoceptor agonist used as an oral inhaled bronchodilator. It is indicated for the treatment of patients with chronic obstructive pulmonary disease (COPD). Synonyms: 5-[(1S)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone. Grade: 95%. CAS No. 1235445-80-3. Molecular formula: C24H28N2O3. Mole weight: 392.499. | |
| 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone | 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone is an indacaterol intermediate used in the preparation of hydroxyquinoline substituted aminoindans. Synonyms: (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one; 5-(2R)-2-Oxiranyl-8-(phenylmethoxy)-2(1H)-quinolinone; (R)-8-Benzyloxy-5-(oxiranyl)carbostyril; 8-(Benzyloxy)-5-((2R)-oxiran-2-yl)quinolin-2(1H)-one. Grade: 95%. CAS No. 173140-90-4. Molecular formula: C18H15NO3. Mole weight: 293.32. | |
| 5-Formyl-8-hydroxycarbostyril | An impurity of Indacaterol. Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36. Synonyms: 8-Hydroxy-2-oxo-1,2-dihydroquinoline-5-carbaldehyde; 1,2-Dihydro-8-hydroxy-2-oxo-5-quinolinecarboxaldehyde; Indacaterol Impurity 01. CAS No. 68304-21-2. Molecular formula: C10H7NO3. Mole weight: 189.17. | |
| Abediterol | Abediterol, also known as LAS100977, is a novel potent, long-acting inhaled β(2)-adrenoceptor agonist in development for the treatment of asthma and chronic obstructive pulmonary disease. Abediterol shows subnanomolar affinity for the human β(2)-adrenoceptor and a functional selectivity over β(1)-adrenoceptors higher than that of formoterol and indacaterol in both a cellular model with overexpressed human receptors and isolated guinea pig tissue. Abediterol is a full agonist at the human β(2)-adrenoceptor (E(max) = 91 ± 5% of the maximal effect of isoprenaline). The potency and onset of action that abediterol shows in isolated human bronchi (EC(50) = 1.9 ± 0.4 nM; t½ onset=7-10 min) is not significantly different from that of formoterol, but its duration of action (t½ ~ 690 min) is similar to that of indacaterol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: LAS100977; LAS-100977; LAS 100977; Abediterol. Product Category: Agonists. Appearance: Solid powder. CAS No. 915133-65-2. Molecular formula: C25H30F2N2O4. Mole weight: 460.52. Purity: >98%. IUPACName: 5-((1R)-2-((6-(2,2-Difluoro-2-phenylethoxy)hexyl)amino)-1-hydroxyethyl)-8- hydroxyquinolin-2(1H)-one. Canonical SMILES: O=C1NC2=C(C([C@@H](O)CNCCCCCCOCC(F)(F)C3=CC=CC=C3)=CC=C2O)C=C1. Product ID: ACM915133652. Alfa Chemistry ISO 9001:2015 Certified. |  |
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