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Indacaterol. Group: Biochemicals. Alternative Names: 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone; QAB 149. Grades: Highly Purified. CAS No. 312753-06-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C24H28N2O3. US Biological Life Sciences.
Worldwide
Indacaterol
Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312753-06-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14299.
Indacaterol Acetate
Indacaterol Acetate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1000160-96-2. Molecular Formula: C26H32N2O5. Mole Weight: 452.55. Catalog: APB1000160962.
Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol maleate inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QAB149. CAS No. 753498-25-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14299A.
Indacaterol Maleate
Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36. Synonyms: 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone Maleic Acid; QAB 149 Maleic Acid; Onbrez. Grades: >98%. CAS No. 753498-25-8. Molecular formula: C24H28N2O3.C4H4O4. Mole weight: 508.56.
Indacaterol Maleate
Indacaterol Maleate. Group: Biochemicals. Grades: Highly Purified. CAS No. 753498-25-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C24H28N2O3·C4H4O4. US Biological Life Sciences.
Worldwide
Indacaterol (maleate) (Standard)
Indacaterol (maleate) (Standard) is the analytical standard of Indacaterol (maleate). This product is intended for research and analytical applications. Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol maleate inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 753498-25-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14299AR.
Indacaterol Maleic Acid Salt
A long-acting β2 adrenoreceptor agonist and bronchodilator, for the treatment of asthma and chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone Maleic Acid; QAB 149 Maleic Acid; Onbrez. Grades: Highly Purified. CAS No. 753498-25-8. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Indacaterol Oxo Impurity
Indacaterol Oxo Impurity. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C24H26N2O4. Mole Weight: 406.48. Catalog: APB10578.
(S)-Indacaterol
An isomerous impurity of Indacaterol. Indacaterol is an ultra-long-acting β-adrenoceptor agonist used as an oral inhaled bronchodilator. It is indicated for the treatment of patients with chronic obstructive pulmonary disease (COPD). Synonyms: 5-[(1S)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-2(1H)-quinolinone. Grades: 95%. CAS No. 1235445-80-3. Molecular formula: C24H28N2O3. Mole weight: 392.499.
Abediterol
Abediterol, also known as LAS100977, is a novel potent, long-acting inhaled β(2)-adrenoceptor agonist in development for the treatment of asthma and chronic obstructive pulmonary disease. Abediterol shows subnanomolar affinity for the human β(2)-adrenoceptor and a functional selectivity over β(1)-adrenoceptors higher than that of formoterol and indacaterol in both a cellular model with overexpressed human receptors and isolated guinea pig tissue. Abediterol is a full agonist at the human β(2)-adrenoceptor (E(max) = 91 ± 5% of the maximal effect of isoprenaline). The potency and onset of action that abediterol shows in isolated human bronchi (EC(50) = 1.9 ± 0.4 nM; t½ onset=7-10 min) is not significantly different from that of formoterol, but its duration of action (t½ ~ 690 min) is similar to that of indacaterol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: LAS100977; LAS-100977; LAS 100977; Abediterol. Product Category: Agonists. Appearance: Solid powder. CAS No. 915133-65-2. Molecular formula: C25H30F2N2O4. Mole weight: 460.52. Purity: >98%. IUPACName: 5-((1R)-2-((6-(2,2-Difluoro-2-phenylethoxy)hexyl)amino)-1-hydroxyethyl)-8- hydroxyquinolin-2(1H)-one. Canonical SMILES: O=C1NC2=C(C([C@@H](O)CNCCCCCCOCC(F)(F)C3=CC=CC=C3)=CC=C2O)C=C1. Product ID: ACM915133652. Alfa Chemistry ISO 9001:2015 Certified.
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