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| Product | Description | |
|---|---|---|
| Indibulin | Indibulin, also called D 24851, estabilizes tubulin polymerization (IC50 = 0.3 μM) and induces tumor cell cycle arrest and apoptosis. In vitro: blocking cell cycle progression at metaphase; In vivo: induce complete tumor remission in the Yoshida AH13 rat sarcoma model. Synonyms: 2-[1-[(4-chlorophenyl)methyl]indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide; D 24851; D-24851; indibulin; N-(pyridin-4-yl)-(1-(4-chlorobenzyl)indol-3-yl)glycoxylamide; N-(pyridin-4-yl)-(1-(4-chlorobenzyl)indol-3-yl)glyoxylamide. CAS No. 204205-90-3. Molecular formula: C22H16ClN3O2. Mole weight: 389.83. |  |
| Indibulin | Indibulin. Group: Biochemicals. Grades: Purified. CAS No. 204205-90-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Indibulin | Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZIO 301; D 24851. CAS No. 204205-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13649. |  |
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