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| Product | Description | |
|---|---|---|
| Indinavir sulfate | Indinavir is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV infection and AIDS. It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM. However, indinavir demonstrates up to a 50-fold loss in potency against the HIV-1 protease drug-resistant mutations PRL24I, PRI50V, and PRG73S (Kis = 1.4, 27, and 0.55 nM). Uses: Hiv protease inhibitors. Synonyms: Crixivan sulfate; MK-639 sulfate; L-735524 sulfate; MK639 sulfate; L735524 sulfate; MK 639 sulfate; L 735524 sulfate. Grades: >98%. CAS No. 157810-81-6. Molecular formula: C36H49N5O8S. Mole weight: 711.87. |  |
| Indinavir sulfate | Indinavir sulfate (MK-639) is an orally active and selective HIV-1 protease inhibitor with a K i of 0.54 nM for PR. Indinavir sulfate exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir sulfate is also a SARS-CoV 3CL pro inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-639; L735524. CAS No. 157810-81-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0689A. |  |
| Indinavir Sulfate (MK-639, Crixivan) | Indinavir Sulfate is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Antiviral. It is a COVID19-related research product. Group: Biochemicals. Alternative Names: 2, 3, 5-Trideoxy-N-[ (1S, 2R) -2, 3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[ (2S) -2[[ (1, 1-dimethylethyl) amino]carbonyl]-4- (3-pyridinylmethyl) -1-piperazinyl]-2- (phenylmethyl) -D-erythro-pentonamide; MK-639; Crixivan. Grades: Highly Purified. CAS No. 157810-81-6. Pack Sizes: 5mg, 25mg, 50mg, 100mg. Molecular Formula: C36H47N5O4 H2SO4, Molecular Weight: 711.87. US Biological Life Sciences. |  Worldwide |
| Indinavir sulfate salt hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Atazanavir | Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Synonyms: Atazanavir ; Reyataz ; Atazanavir sulfate ; CGP75136 ; CGP75176 ; CGP75355 ; BMS232632 ; CGP 73547 ; CGP 75136 ; CGP 75176 ; CGP 75355 ; CGP-73547 ; CGP-75136 ; CGP-75176 ; CGP-75355 ; BMS 232632 ; BMS-232632 ; BMS-232632-05 ; C413408. Grades: 0.98. CAS No. 198904-31-3. Molecular formula: C38H52N6O7. Mole weight: 704.869. | |
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