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| Product | Description | |
|---|---|---|
| Indirubin-3'-monoxime | Indirubin-3'-monoxime, a chemical derivative of indirubin, is an inhibitor of GSK-3β with dual affinity for CDK1/5 receptor. It significantly inhibited the proliferation and induced apoptosis in all of the RCC cell lines. IC50: GSK-3β= 22nM; CDK1/5= 180/1. Synonyms: 3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one INDIRUBIN-3'-MONOXIME indirubin-3'-oxime 160807-49-8 indirubin-3-oxime Indirubin-3monoxime indirubin-3'-monooxime 3-[3-(Hydroxyamino)-1H-indol-2-yl]indol-2-one Indirubin-3'-monoxime CHEMBL126077 CHEBI:43. CAS No. 160807-49-8. Molecular formula: C16H11N3O2. Mole weight: 277.28. |  |
| Indirubin-3'-monoxime | Indirubin-3'-monoxime. Group: Biochemicals. Alternative Names: Indirubin-3'-oxime; 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one. Grades: Highly Purified. CAS No. 160807-49-8. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H11N3O2. US Biological Life Sciences. |  Worldwide |
| Indirubin-3'-monoxime | Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and weakly inhibits 5-Lipoxygenase , with IC 50 s of 22 nM and 7.8-10 μM, respectively; Indirubin-3'-monoxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC 50 s of 100 and 180 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Indirubin-3'-oxime. CAS No. 160807-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19807. |  |
| Indirubin-3?-monoxime-5-sulphonic Acid - CAS 331467-05-1 | A potent, reversible, and selective inhibitor of Cdk1 (IC?? = 5 nM) and Cdk5 (IC?? = 7 nM) and glycogen synthase kinase-3? (GSK-3?; IC?? = 80 nM). Group: Fluorescence/luminescence spectroscopy. |  |
| Indirubin-3?-monoxime - CAS 160807-49-8 | A potent, reversible, and ATP-compatible inhibitor of GSK-3? (glycogen synthase kinase 3?), Cdk1 (cyclin-dependent kinase1) and Cdk5 (IC?? = 22 nM, 180 nM, and 100 nM, respectively). Group: Fluorescence/luminescence spectroscopy. | |
| Indirubin-3-monoxime (Indirubin-3-oxime) | A potent inhibitor of GSK-3ß (IC50=22nM). Also inhibits CDK1 (IC50=180nM) and CDK (IC50=100nM). It reversibly arrests asynchronous HBL-100 cells at G2. It induces apoptosis in the mammary carcinoma cell line MCF-7 (10üM). Group: Biochemicals. Alternative Names: Indirubin-3-oxime. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
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